Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Peter Hawryluk"'
Autor:
Servane Lachize, Carlos A. Obejero-Paz, Shushant Jain, Tiffany Snow, Andrew Bruening-Wright, Peter Hawryluk
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 105:106815
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::101dc857bae03531a7a10ecffbd5cf75
https://doi.org/10.1016/j.vascn.2020.106815
https://doi.org/10.1016/j.vascn.2020.106815
Autor:
Arthur M. Brown, James Kramer, Peter Hawryluk, Howard C. Dittrich, Milos Tatalovic, Carlos A. Obejero-Paz, Andrew Bruening-Wright
Publikováno v:
Scientific Reports
Vanoxerine has been in clinical trials for Parkinsonism, depression and cocaine addiction but lacked efficacy. Although a potent blocker of hERG, it produced no serious adverse events. We attributed the unexpected result to offsetting Multiple Ion Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967d1410d7c4a03dc5de2777b638dc06
http://europepmc.org/articles/PMC4663487
http://europepmc.org/articles/PMC4663487
Autor:
Barbara A. Wible, Peter Hawryluk, Glenn E. Kirsch, Eckhard Ficker, Yuri A. Kuryshev, Arthur Brown
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 52:136-145
Direct block of I(Kr) by non-antiarrhythmic drugs (NARDs) is a major cause of QT prolongation and torsades de pointes (TdP), and has made the hERG potassium channel a major target of drug safety programs in cardiotoxicity. Block of hERG currents is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e283aea46b122236d78725dcae44531b
https://doi.org/10.1016/j.vascn.2005.03.008
https://doi.org/10.1016/j.vascn.2005.03.008
Autor:
Adrienne T. Dennis, Lu Wang, Carlos A. Obejero-Paz, Peter Hawryluk, Eckhard Ficker, Yuri A. Kuryshev, Arthur M. Brown, Barbara A. Wible
Publikováno v:
Molecular Pharmacology. 66:33-44
Arsenic trioxide (As(2)O(3)) produces dramatic remissions in patients with relapsed or refractory acute promyelocytic leukemia. Its clinical use is burdened by QT prolongation, torsade de pointes, and sudden cardiac death. In the present study, we an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4c5f475c743bbc168e0b1b237a0554
https://doi.org/10.1124/mol.66.1.33
https://doi.org/10.1124/mol.66.1.33
Autor:
Peter Hawryluk, James Kramer, Yuri A. Kuryshev, Luke Armstrong, Abby Sewell, Arthur M. Brown, Carlos A. Obejero-Paz, Caiyun Wu
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 88:199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::521147fbe06cfd08ccbc7f094fb67630
https://doi.org/10.1016/j.vascn.2017.09.102
https://doi.org/10.1016/j.vascn.2017.09.102
Autor:
Jiesheng Kang, Barbara A. Wible, Eckhard Ficker, Xiao Liang Chen, Kaoru Sawamura, Lu Wang, David Rampe, Peter Hawryluk, Yuri A. Kuryshev, Arthur M. Brown, Adrienne T. Dennis, William P. Reynolds
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 312(1)
The diamidine pentamidine is used to treat leishmaniasis, trypanosomiasis, and Pneumocystis carinii pneumonia. Treatment may be accompanied by prolongation of the QT interval of the electrocardiogram and torsades de pointes tachycardias. Up to now, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e27020d4ebfd74b353465c06a9d70b
https://pubmed.ncbi.nlm.nih.gov/15340016
https://pubmed.ncbi.nlm.nih.gov/15340016
Autor:
A, Kuryshev Yuri, Eckhard, Ficker, Lu, Wang, Peter, Hawryluk, T, Dennis Adrienne, A, Wible Barbara, M, Brown Arthur, Jiesheng, Kang, Xiao-Liang, Chen, Kaoru, Sawamura, William, Reynolds, David, Rampe
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; January 2005, Vol. 312 Issue: 1 p316-23, 8p
Autor:
Eckhard, Ficker, A, Kuryshev Yuri, T, Dennis Adrienne, Carlos, Obejero-Paz, Lu, Wang, Peter, Hawryluk, A, Wible Barbara, M, Brown Arthur
Publikováno v:
Molecular Pharmacology; July 2004, Vol. 66 Issue: 1 p33-44, 12p