Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Peter Hans Ermann"'
Autor:
Mayra B. Reyes, Simon Leung, Zenrong Gao, Theo Denzel, Chiajen Lai, Jack Z. Gougoutas, Mark Lindrud, Kevin J. Volk, Thomas P. Kissick, Victor W. Rosso, Gerard A. Crispino, Wei Meng, Pricilla Richberg, Prashant P. Deshpande, William N. Washburn, Mueller Richard H, David Hughes, Hidegard Lobinger, Renee Randazzo, Peter Hans Ermann, Michael E. Randazzo, Wendel W. Doubleday, Michael Fakes, Annie Pullockaran, Frederic G. Buono, Bruce A. Ellsworth, Janak Singh, John D. Dimarco
Publikováno v:
Organic Process Research & Development. 16:577-585
A practical synthesis of the SGLT-2 inhibitor β-C-aryl-d-glucoside (1) has been developed. The route employed 2,3,4,6-tetra-O-trimethlysilyl-d-glucano-1,5-lactone as the key chiral building block, prepared efficiently from the commercially available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1fbf64e633a66849c3bae734a3b4e43
https://doi.org/10.1021/op200306q
https://doi.org/10.1021/op200306q
Autor:
David R. Kronenthal, Joydeep Kant, Peter Hans Ermann, Ramakrishnan Chidambaram, Jason Zhu, Peter Schierling, Lajeunesse Jean, Peter Sung Keun Lee, Pierre Sirard
Publikováno v:
Organic Process Research & Development. 6:632-636
A novel synthesis of 1 (BMS-270394), a nuclear retinoic acid receptor (RARγ) agonist, is reported. The synthesis includes an enantioselective reduction of α-ketoacid 4 to the corresponding chiral α-hydroxy acid 7 using a NaBH4/l-tartaric acid mixt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09e80a0dd9c7c75e547b88402876fa98
https://doi.org/10.1021/op0202134
https://doi.org/10.1021/op0202134
Autor:
John D. Dimarco, Shankar Swaminathan, Brian Burke, Thomas P. Kissick, Oak K. Kim, Bin Zheng, Janak Singh, Kenneth J. Natalie, Goodrich Jason, Juliya Livshits, Matthew A. Brown, John A. Grosso, Zhinong Gao, Michael J. Humora, Anthony P. Dutka, Peter Hans Ermann, David R. Kronenthal, Gerard A. Crispino, Richard H. Mueller, John A. Wichtowski, Jeffrey T. North, Joanne J. Bronson, Jack Z. Gougoutas, Yasutsugu Ueda, Dane M. Springer, Peter Schierling, Bing Yu Luh, James E. Heikes, Dau-Ming Hsieh, Anne J. Pullockaran, Bo Zhang, Robert K. Perrone, Mei C. Lai, and Theodor W. Denzel, Yunhui Zhang
Publikováno v:
Organic Process Research & Development. 4:488-497
A practical synthesis of the anti-methicillin resistant Staphylococcus aureus cephem (6R-trans)-E-7-[[[[2,5-dichloro-4-[3-[(carboxymethyl)amino]-3-oxo-1-propenyl]phenyl]-thio]-acetyl]amino]-4-[[(2-carboxy-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::030fc232263c59de1340816a124920ab
https://doi.org/10.1021/op0002850
https://doi.org/10.1021/op0002850