Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Peter Hafkemeyer"'
Autor:
E. Walter, Winfried V. Kern, Hans Christian Spangenberg, Gerhild Becker, Fritz von Weizsäcker, Robert Thimme, Roman Huber, Thomas Baumert, Peter Hafkemeyer, Christian N. Arnold, Leonhard Mohr, Michael Geißler, S Offensperger, Markus H. Heim, Darius Moradpour, W.-B. Offensperger, Hans-Peter Allgaier, Jan Harder
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 143:40-45
Autor:
Hans-Peter, Allgaier, Christian, Arnold, Thomas F, Baumert, Gerhild, Becker, Michael, Geißler, Peter, Hafkemeyer, Jan, Harder, Markus H, Heim, Roman, Huber, Winfried V, Kern, Leonhard, Mohr, Darius, Moradpour, Silke, Offensperger, Wolf-Bernhard, Offensperger, Hans Christian, Spangenberg, Robert, Thimme, Eike, Walter, Fritz, von Weizsäcker
Publikováno v:
Deutsche medizinische Wochenschrift (1946). 143(1)
Publikováno v:
Journal of Biological Chemistry. 278:18132-18139
The human multidrug transporter P-glycoprotein (Pgp, ABCB1) contributes to the poor bioavailability of many anticancer and antimicrobial agents as well as to drug resistance at the cellular level. For rational design of effective Pgp inhibitors, a cl
Autor:
Hubert E. Blum, Yvonne Folmer, C. Fulda, Michaela Schneider, Peter Hafkemeyer, Matthes Huesker
Publikováno v:
Hepatology. 36:874-884
Human cancers, including hepatocellular carcinoma (HCC), are characterized by a high degree of drug resistance. The multidrug resistance (MDR) transporters MDR1-P-glycoprotein and MRP2 (multidrug-associated protein 2) are expressed in almost 50% of h
Publikováno v:
Human Gene Therapy. 10:923-934
The rapid progress in gene therapy has expanded our ability to alter genetic structure, necessitating the development of methods for detecting the activity of new vectors. The central concept of a reporter gene is simple: it is a defined nucleotide s
Autor:
Saibal Dey, Michael M. Gottesman, Peter Hafkemeyer, Ira Pastan, Christine A. Hrycyna, Suresh V. Ambudkar
Publikováno v:
Biochemistry. 37:16400-16409
P-glycoprotein (Pgp), the product of the MDR1 gene, confers multidrug resistance on cancer cells by ATP-dependent extrusion of anticancer drugs. Biochemical and genetic studies with Pgp have identified the putative transmembrane (TM) region 12 (resid
Autor:
Hideyuki Kojima, Masahito Uemura, Ulrike Buchholz, Hiroshi Fukui, Tadasu Tsujii, Andrea Keppler, Dietrich Keppler, Peter Hafkemeyer
Publikováno v:
Hepatology. 20:804-812
The significance of cysteinyl leukotrienes was investigated in patients with liver diseases by measurements of leukotriene E4 and N-acetyl-leukotriene E4 in urine. A marked increase of renal cysteinyl leukotriene excretion was observed in patients wi
Autor:
E. Matthes, Burkhard Costisella, M. Von Janta-Lipinski, U. Huebscher, Peter Hafkemeyer, H. Ochs
Publikováno v:
ChemInform. 29
Autor:
Gláucia Paranhos-Baccalà, Mirjam B. Zeisel, Françoise Stoll-Keller, Marco Hoffmann, Nikolaus Jilg, Philipp Henneke, Thomas F. Baumert, Heidi Barth, Hubert E. Blum, Takaji Wakita, Peter Hafkemeyer
Publikováno v:
Journal of Innate Immunity
Journal of Innate Immunity, Karger, 2009, 1 (5), pp.446-54. ⟨10.1159/000226136⟩
Journal of Innate Immunity, 2009, 1 (5), pp.446-54. ⟨10.1159/000226136⟩
Journal of Innate Immunity, Karger, 2009, 1 (5), pp.446-54. ⟨10.1159/000226136⟩
Journal of Innate Immunity, 2009, 1 (5), pp.446-54. ⟨10.1159/000226136⟩
International audience; Toll-like receptors (TLRs) are pathogen recognition molecules activating the innate immune system. Cell surface expressed TLRs, such as TLR2 and TLR4, have been shown to play an important role in human host defenses against vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1787ca10b65ba945fa901b23399864
https://www.hal.inserm.fr/inserm-00516966/file/inserm-00516966_edited.pdf
https://www.hal.inserm.fr/inserm-00516966/file/inserm-00516966_edited.pdf
Publikováno v:
Proceedings of the National Academy of Sciences. 88:5262-5266
The reverse transcriptase of human immunodeficiency virus type 1 is a heterodimeric protein consisting of two polypeptides with masses of 66 and 51 kDa and has, as a second enzymatic activity, RNase H activity. The 66-kDa polypeptide can be cleaved b