Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Peter H. U. Lee"'
Autor:
Emma Barrett, Gabrielle Ivey, Adam Cunningham, Gary Coffman, Tyera Pemberton, Chan Lee, Prabir Patra, James B. Day, Peter H. U. Lee, Joon W. Shim
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The glucagon-like peptide-1 receptor (GLP-1R) agonists reduce glycated hemoglobin in patients with type 2 diabetes. Mounting evidence indicates that the potential of GLP-1R agonists, mimicking a 30 amino acid ligand, GLP-1, extends to the treatment o
Externí odkaz:
https://doaj.org/article/a2169a78ce0d4aaba362d9008ac9c48e
Autor:
Zhanping Ren, Eun Hyun Ahn, Minjae Do, Devin B. Mair, Amir Monemianesfahani, Peter H. U. Lee, Deok-Ho Kim
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract While the effects of microgravity on inducing skeletal muscle atrophy have been extensively studied, the impacts of microgravity on myogenesis and its mechanisms remain unclear. In this study, we developed a microphysiological system of engi
Externí odkaz:
https://doaj.org/article/fd5bdb1273714bb2a8541f436dddadac
Autor:
Ian McKnight, Regan Raines, Hunter White, Nasim Nosoudi, Chan Lee, Peter H U Lee, Joon W Shim
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283470 (2023)
Mutations of protein kinases and cytokines are common and can cause cancer and other diseases. However, our understanding of the mutability in these genes remains rudimentary. Therefore, given previously known factors which are associated with high m
Externí odkaz:
https://doaj.org/article/2bc6819048674115b013b8e8c04523c6
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Heart disease remains the leading cause of mortality globally, so further investigation is required to identify its underlying mechanisms and potential targets for treatment and prevention. Mitsugumin 53 (MG53), also known as TRIM72, is a TR
Externí odkaz:
https://doaj.org/article/2085b7e4e34f4b278e811d8ce4ec488a
Autor:
Regan Raines, Ian McKnight, Hunter White, Kaitlyn Legg, Chan Lee, Wei Li, Peter H. U. Lee, Joon W. Shim
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 594 (2022)
Mutations of ion channels and G-protein-coupled receptors (GPCRs) are not uncommon and can lead to cardiovascular diseases. Given previously reported multiple factors associated with high mutation rates, we sorted the relative mutability of multiple
Externí odkaz:
https://doaj.org/article/b7dbb1df400c453eba04fc37f4f19f39
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Since its identification in 2009, multiple studies have indicated the importance of MG53 in muscle physiology. The protein is produced in striated muscles but has physiologic implications reaching beyond the confines of striated muscles. Roles in mus
Externí odkaz:
https://doaj.org/article/db71febb1f37417ca8a4d724740225a0
Autor:
Hunter, White, Ryan, Webb, Ian, McKnight, Kaitlyn, Legg, Chan, Lee, Peter H U, Lee, Olivia Smith, Spicer, Joon W, Shim
Publikováno v:
Frontiers in Genetics. 13
Symptoms of normal pressure hydrocephalus (NPH) and Alzheimer’s disease (AD) are somewhat similar, and it is common to misdiagnose these two conditions. Although there are fluid markers detectable in humans with NPH and AD, determining which biomar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bfc2a71e2c28ddc3a1ffa813c0f57da
https://doi.org/10.3389/fgene.2022.936151
https://doi.org/10.3389/fgene.2022.936151
Autor:
Devin B. Mair, Marcus Alonso Cee Williams, Jeffrey Fanzhi Chen, Alex Goldstein, Alex Wu, Peter H. U. Lee, Nathan J. Sniadecki, Deok-Ho Kim
Publikováno v:
ACS applied materialsinterfaces. 14(34)
Poly(dimethylsiloxane) (PDMS) is a commonly used polymer in organ-on-a-chip devices and microphysiological systems. However, due to its hydrophobicity and permeability, it absorbs drug compounds, preventing accurate drug screening applications. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9452214190ab925516df4eb03cc1d92d
https://pubmed.ncbi.nlm.nih.gov/35984038
https://pubmed.ncbi.nlm.nih.gov/35984038
Publikováno v:
American journal of physiology. Cell physiology. 322(3)
Skeletal muscle atrophy is a well-known consequence of spaceflight. Because of the potential significant impact of muscle atrophy and muscle dysfunction on astronauts and their mission, a thorough understanding of the mechanisms of this atrophy and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8729f16a3f28020c978b0eab90e21d
https://pubmed.ncbi.nlm.nih.gov/35171699
https://pubmed.ncbi.nlm.nih.gov/35171699
Publikováno v:
Case Reports in Surgery, Vol 2015 (2015)
Septic pulmonary emboli (SPE) can be a difficult clinical entity to distinguish from thromboembolic pulmonary embolism (TPE) in a patient with history of IV drug abuse (IVDA). We present a case of a patient who presented with failure to thrive and pr
Externí odkaz:
https://doaj.org/article/a739a671d6574f32a5d3d8d427a9b30f