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pro vyhledávání: '"Peter H. Roos"'
Autor:
Peter H. Roos
Publikováno v:
Peter H. Roos
Species of the butterfly subfamily Danainae visit orchids, resulting in pollinaria being attached to their heads. In several habitats in east Sulawesi a remarkable percentage of Danainae specimens was observed with orchid pollinaria preferentially at
Autor:
Ernst Petzinger, Christine Jäckh, Barbara Döring, Eric Fabian, Stefanie Hessel, Peter H. Roos, Carsten Goebel, Alfonso Lampen, Ulrike Bernauer, Ursula Gundert-Remy, Franz Oesch, Brunhilde Blömeke, Wolfgang Völkel
Publikováno v:
Drug Metabolism Reviews. 46:291-324
In general, xenobiotic metabolizing enzymes (XMEs) are expressed in lower levels in the extrahepatic tissues than in the liver, making the former less relevant for the clearance of xenobiotics. Local metabolism, however, may lead to tissue-specific a
Autor:
Manuela van Liempt, Sandra Rode, Kathrin Herbst, Jeanette Niestroy, Peter H. Roos, Alfonso Barbara
Publikováno v:
Toxicology in Vitro. 25:671-683
As phytochemicals have the potential to counteract adverse effects of carcinogens we investigated the influence of the flavonoids quercetin and kaempferol on benzo[a]pyrene (BaP) mediated effects on human colon cancer cells, Caco-2. We focused on con
Publikováno v:
J. Anal. At. Spectrom.. 26:310-319
Quantitative analysis of cytochrome P450 (CYP) patterns of cells and tissues is an important aspect in toxicological and pharmacological research as this group of enzymes is largely involved in the metabolism of toxic compounds and drugs. Here we pre
Autor:
Peter H. Roos, Christina U. Köhler
Publikováno v:
Analytical and Bioanalytical Chemistry. 392:1109-1122
The scattered and limited data on hnRNAs (pre-mRNAs) of cytochromes P450 (CYP) are compiled and discussed for the first time. The methods for determination and quantification of hnRNAs are compared. In most cases, CYP hnRNA levels were determined as
Autor:
Sabine Plöttner, Jan G. Hengstler, Gisela H. Degen, Silvia Selinski, Wolfram Föllmann, Peter H. Roos, Hermann M. Bolt
Publikováno v:
Archives of Toxicology. 83:131-138
Cultured primary porcine urinary bladder epithelial cells (PUBEC) represent an adequate and easy to handle in vitro system for studies of urothelial toxicity. PUBEC maintain in vivo-like metabolic activities and physiological functions. They express
Autor:
Peter H. Roos, Andreas Manz, Norbert Jakubowski, Christina U. Koehler, Larissa Waentig, Arunachalam Venkatachalam
Publikováno v:
Analytical and Bioanalytical Chemistry. 392:1135-1147
Numerous structurally and enzymatically similar cytochromes P450 (CYPs) are involved in the metabolism of xenobiotics and are present in different amounts and with different enzyme profiles in human tissues and cells. Analysis of their adaptively reg
Publikováno v:
International Journal of Hygiene and Environmental Health. 211:74-81
In the present study, the genotoxicity of acrylamide (AA) was investigated in HepG2 cells using SCGE. Additionally, the influence of ethanol on the modulation of AA-induced DNA-migration caused by CYP2E1-upregulation and/or GSH-depletion was examined
Publikováno v:
Archives of Toxicology. 81:19-25
Polycyclic aromatic hydrocarbons, arylamines and nitrosamines, constituents of cigarette smoke, are known inducers of bladder cancer. The biochemical response of the target tissue, the bladder urothelium, following inhalation of cigarette smoke has n
Publikováno v:
Sector Field Mass Spectrometry for Elemental and Isotopic Analysis ISBN: 9781849733922
Inductively coupled plasma mass spectrometry (ICP-MS) is a mass spectrometric method for detection of ions generated in an atmospheric plasma ion source. It provides multi-elemental detection of most elements of the periodic table combined with high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91488494ca49d03c7dda0cf1cf9594bb
https://doi.org/10.1039/9781849735407-00208
https://doi.org/10.1039/9781849735407-00208