Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Peter H. Redfern"'
Publikováno v:
European Journal of Pharmacology. 567:102-109
Tobacco smoking is a nicotine addiction, mediated in part by the ability of nicotine to elicit dopamine release, as a result of the stimulation of nicotinic acetylcholine receptors associated with dopaminergic pathways. The smoking cessation agent bu
Autor:
P J Mitchell, Peter H. Redfern
Publikováno v:
Current Pharmaceutical Design. 11:171-203
A wide diversity of animal models has been used to examine antidepressant activity. These range from relatively simple models sensitive to acute treatment, to highly sophisticated models that reputedly model some aspect of depressive illness and whic
Publikováno v:
Nicotine & Tobacco Research. 6:869-889
Autor:
Peter H. Redfern, B. Lemmer
Measured by any criteria, research in chronobiology in general and chronopharmacology in particular has expanded rapidly in recent years. This expansion has been paralleled by an increasing recognition by those outside the field of the relevance and
Publikováno v:
Neuropharmacology. 44:911-925
The aim of this study was to determine whether electroconvulsive shock (ECS, an established antidepressant treatment), like acute and chronic antidepressant drug treatments, produces similar differential effects on the behavioural profile of resident
Publikováno v:
British Journal of Pharmacology. 131:1569-1576
Intracerebral microdialysis was used to examine the function of the terminal 5-hydroxytryptamine1B (5-HT1B) autoreceptor in the region of the suprachiasmatic nuclei (SCN) of freely moving conscious rats at six time points or zeitgeber times (ZTs) acr
Publikováno v:
British Journal of Pharmacology. 126:1777-1784
Intracerebral microdialysis was used to examine the function of the terminal 5-hydroxytryptamine (5-HT) autoreceptor in the anterior hypothalamus of anaesthetized rats at two points in the light phase of the light–dark cycle. Infusion of the 5-HT1A
Publikováno v:
Pharmaceutical Science & Technology Today. 1:54-61
The revolution in computer technology has been all pervasive. In the pharmaceutical industry, computer technology has been put to effective use in automation of many aspects of research and development. At the same time there has been a dramatic incr
Publikováno v:
Drug Development Research. 38:149-159
Nicotine, acting through nicotinic acetylcholine receptors (nAChR) located on nerve terminals, can evoke the release of various neurotransmitters in the brain. The presynaptic nicotinic stimulation of acetylcholine release, demonstrated in cortical a
Publikováno v:
Neuropharmacology. 35:1531-1536
Recent observations from synaptosome preparations have questioned the tetrodotoxin (TTX) insensitivity of nicotine-evoked dopamine release in the striatum, a characteristic previously considered diagnostic of presynaptically located nicotinic acetylc