Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter H. Liu"'
Autor:
Peter H. Liu, Samuel Sidi
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Antitumor immunity has emerged as a favorable byproduct of radiation therapy (RT), whereby tumor-associated antigens released from irradiated cells unleash innate and adaptive attacks on tumors located both within and outside the radiation field. RT-
Externí odkaz:
https://doaj.org/article/9fa2a59629304891a3673ee844c0aeb8
Autor:
Daniel M. Labow, Deepa R. Magge, Natasha DeNicola, Peter H. Liu, Benjamin J. Golas, Umut Sarpel, Daniel Solomon, Samantha N. Aycart, Daniela Feingold
Publikováno v:
Journal of Surgical Oncology. 119:758-765
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is effective in select patients with peritoneal carcinomatosis (PC). Signet ring cell (SRC) pathology is associated with poor prognosis. The role of CRS/HIPEC in this pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2393939d8eca9ff4beb3691f88d1f1bf
https://doi.org/10.1002/jso.25379
https://doi.org/10.1002/jso.25379
Autor:
Xiao Zhen Zhou, Richard M. White, Ruth Thompson, Peter Man-Un Ung, Samuel Sidi, Peter H. Liu, John V. Heymach, Richa B. Shah, Julio A. Aguirre-Ghiso, Arshi Arora, Shingo Kozono, Yuanyuan Li, Heath D. Skinner, Robert G. Maki, John M. Barbaro, Vincent Brechin, Avner Schlessinger, Kun Ping Lu, Elisa de Stanchina, Andrej Gorbatenko, Jose M. Silva, Katherine S. Panageas, Renuka Raman
Publikováno v:
Nature cell biology
Drug-based strategies to overcome tumour resistance to radiotherapy (R-RT) remain limited by the single-agent toxicity of traditional radiosensitizers (for example, platinums) and a lack of targeted alternatives. In a screen for compounds that restor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191c597356481907ed675c6de05ea024
http://europepmc.org/articles/PMC6428421
http://europepmc.org/articles/PMC6428421
Autor:
Kiyohiro Ando, Sara R. Fassio, Ruth Thompson, Sheré L. Paris, Andrew Oberst, Brittany A. Rohrman, Peter H. Liu, Richa B. Shah, Chloé I. Charendoff, Lisa Bouchier-Hayes, Melissa J. Parsons, Samuel Sidi
Publikováno v:
Journal of Cell Biology. 216:1795-1810
The PIDDosome (PIDD–RAIDD–caspase-2 complex) is considered to be the primary signaling platform for caspase-2 activation in response to genotoxic stress. Yet studies of PIDD-deficient mice show that caspase-2 activation can proceed in the absence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af974461c36a3bafcbe1fd42840f4ba2
https://doi.org/10.1083/jcb.201608095
https://doi.org/10.1083/jcb.201608095
Publikováno v:
Gastroenterology. 160:S-887
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69a41d337c8fe693f41917516ae0e067
https://doi.org/10.1016/s0016-5085(21)02852-3
https://doi.org/10.1016/s0016-5085(21)02852-3
Autor:
Ruth Thompson, Yogesh K. Gupta, Samuel Sidi, Aneel K. Aggarwal, Peter H. Liu, Kiyohiro Ando, Richa B. Shah
Publikováno v:
Molecular Cell. 58(5):767-779
SUMMARY The PIDDosome—PIDD-RAIDD-caspase-2 complex—is a proapoptotic caspase-activation platform of elusive significance. DNA damage can initiate complex assembly via ATM phosphorylation of the PIDD death domain (DD), which enables RAIDD recruitm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebd27d66fb47e1a257c55a6c1987a3d
Autor:
Emmanuelle Logette, A. Thomas Look, Jianlong Wang, Kiyohiro Ando, Jürg Tschopp, Takaomi Sanda, Jennifer L. Kernan, Lisa Bouchier-Hayes, Samuel Sidi, Peter H. Liu
Publikováno v:
Molecular Cell, vol. 47, no. 5, pp. 681-693
Biochemical evidence implicates the death-domain (DD) protein PIDD as a molecular switch capable of signaling cell survival or death in response to genotoxic stress. PIDD activity is determined by binding-partner selection at its DD: whereas recruitm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3835e3ff3af2794a239ffac48d59a480
https://doi.org/10.1016/j.molcel.2012.06.024
https://doi.org/10.1016/j.molcel.2012.06.024