Zobrazeno 1 - 10
of 402
pro vyhledávání: '"Peter H. Howarth"'
Autor:
Valentyna Yasinska, Cristina Gómez, Johan Kolmert, Magnus Ericsson, Anton Pohanka, Anna James, Lars I. Andersson, Maria Sparreman-Mikus, Ana R. Sousa, John H. Riley, Stewart Bates, Per S. Bakke, Nazanin Zounemat Kermani, Massimo Caruso, Pascal Chanez, Stephen J. Fowler, Thomas Geiser, Peter H. Howarth, Ildikó Horváth, Norbert Krug, Paolo Montuschi, Marek Sanak, Annelie Behndig, Dominick E. Shaw, Richard G. Knowles, Barbro Dahlén, Anke-Hilse Maitland-van der Zee, Peter J. Sterk, Ratko Djukanovic, Ian M. Adcock, Kian Fan Chung, Craig E. Wheelock, Sven-Erik Dahlén, Eva Wikström Jonsson, H. Ahmed
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Rationale Patients with severe asthma are dependent upon treatment with high doses of inhaled corticosteroids (ICS) and often also oral corticosteroids (OCS). The extent of endogenous androgenic anabolic steroid (EAAS) suppression in asthma has not p
Externí odkaz:
https://doaj.org/article/a7fc69aad4384962865d87d94aff46ed
Autor:
Ian D. Pavord, Roland Buhl, Monica Kraft, Charlene M. Prazma, Robert G. Price, Peter H. Howarth, Steven W. Yancey
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/76317a21f29a45408905b93037f416d6
Autor:
Uruj Hoda, Stelios Pavlidis, Aruna T. Bansal, Kentaro Takahashi, Sile Hu, Francois Ng Kee Kwong, Christos Rossios, Kai Sun, Pankaj Bhavsar, Matthew Loza, Frederic Baribaud, Pascal Chanez, Stephen J. Fowler, Ildiko Horvath, Paolo Montuschi, Florian Singer, Jacek Musial, Barbro Dahlen, Norbert Krug, Thomas Sandstrom, Dominic E. Shaw, Rene Lutter, Louise J. Fleming, Peter H. Howarth, Massimo Caruso, Ana R. Sousa, Julie Corfield, Charles Auffray, Bertrand De Meulder, Diane Lefaudeux, Sven‐Erik Dahlen, Ratko Djukanovic, Peter J. Sterk, Yike Guo, Ian M. Adcock, Kian Fan Chung, the U‐BIOPRED study group
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 4, Pp n/a-n/a (2022)
Abstract Background Exacerbation‐prone asthma is a feature of severe disease. However, the basis for its persistency remains unclear. Objectives To determine the clinical and transcriptomic features of frequent exacerbators (FEs) and persistent FEs
Externí odkaz:
https://doaj.org/article/472cffbdc9ba4c16ac2d4d6cd89330da
Autor:
Adnan Azim, Faisal I. Rezwan, Clair Barber, Matthew Harvey, Ramesh J. Kurukulaaratchy, John W. Holloway, Peter H. Howarth
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 10, p 1635 (2022)
The measurement of exhaled volatile organic compounds (VOCs) in exhaled breath (breathomics) represents an exciting biomarker matrix for airways disease, with early research indicating a sensitivity to airway inflammation. One of the key aspects to a
Externí odkaz:
https://doaj.org/article/f1eac78313594a2088429a22b8079748
Autor:
Catherine E. Hanratty, John G. Matthews, Joseph R. Arron, David F. Choy, Ian D. Pavord, P. Bradding, Christopher E. Brightling, Rekha Chaudhuri, Douglas C. Cowan, Ratko Djukanovic, Nicola Gallagher, Stephen J. Fowler, Tim C. Hardman, Tim Harrison, Cécile T. Holweg, Peter H. Howarth, James Lordan, Adel H. Mansur, Andrew Menzies-Gow, Sofia Mosesova, Robert M. Niven, Douglas S. Robinson, Dominick E. Shaw, Samantha Walker, Ashley Woodcock, Liam G. Heaney, on behalf of the RASP-UK (Refractory Asthma Stratification Programme) Consortium
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Patients with difficult-to-control asthma consume 50–60% of healthcare costs attributed to asthma and cost approximately five-times more than patients with mild stable disease. Recent evidence demonstrates that not all patients
Externí odkaz:
https://doaj.org/article/8b2b5c94718a45699e6b6b269b64f460
Autor:
Ana S. Francisco-Garcia, Eva M. Garrido-Martín, Hitasha Rupani, Laurie C. K. Lau, Rocio T. Martinez-Nunez, Peter H. Howarth, Tilman Sanchez-Elsner
Publikováno v:
Non-Coding RNA, Vol 5, Iss 4, p 51 (2019)
MicroRNAs are known to regulate important pathways in asthma pathology including the IL-6 and IFN pathways. MicroRNAs have been found not only within cells but also within extracellular vesicles such as exosomes. In this study, we particularly focuse
Externí odkaz:
https://doaj.org/article/6e44121955f34799bb921e957446d686
Autor:
Peter H. Howarth
Publikováno v:
Mediators of Inflammation, Vol 4, Iss 7, Pp S26-S30 (1995)
Levocabastine is a highly potent and selective H1-receptor antagonist specifically developed for topical administration by ocular and nasal routes. The clinical effects of levocabastine occur rapidly and are predominantly due to local antihistaminic
Externí odkaz:
https://doaj.org/article/27da862031814dcb94ffde2f249980f9
Autor:
Claus Bachert, Amber U. Luong, Philippe Gevaert, Joaquim Mullol, Steven G. Smith, Jared Silver, Ana R. Sousa, Peter H. Howarth, Victoria S. Benson, Bhabita Mayer, Robert H. Chan, William W. Busse
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice.
Autor:
Latifa Khalfaoui, Fiona A. Symon, Simon Couillard, Beverley Hargadon, Rekha Chaudhuri, Steve Bicknell, Adel H. Mansur, Rahul Shrimanker, Timothy S. C. Hinks, Ian D. Pavord, Stephen J. Fowler, Vanessa Brown, Lorcan P. McGarvey, Liam G. Heaney, Cary D. Austin, Peter H. Howarth, Joseph R. Arron, David F. Choy, Peter Bradding
Publikováno v:
Khalfaoui, L, Symon, F A, Couillard, S, Hargadon, B, Chaudhuri, R, Bicknell, S, Mansur, A H, Shrimanker, R, Hinks, TS C, Pavord, I D, Fowler, S J, Brown, V, McGarvey, L P, Heaney, L G, Austin, C D, Howarth, P H, Arron, J R, Choy, D F & Bradding, P 2022, ' Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma ', Allergy . https://doi.org/10.1111/all.15376
UK Medical Research Council Refractory Asthma Stratification programme (RASP-UK) 2022, ' Airway remodelling rather than cellular infiltration characterises both type2 cytokine biomarker-high and-low severe asthma ', Allergy . https://doi.org/10.1111/all.15376
UK Medical Research Council Refractory Asthma Stratification programme (RASP-UK) 2022, ' Airway remodelling rather than cellular infiltration characterises both type2 cytokine biomarker-high and-low severe asthma ', Allergy . https://doi.org/10.1111/all.15376
Background: The most recognizable phenotype of severe asthma comprises people who are blood eosinophil and FeNO-high, driven by type-2 (T2) cytokine biology which responds to targeted biological therapies. However, in many people with severe asthma,
Autor:
Wytske J. Fokkens, Joaquim Mullol, David Kennedy, Carl Philpott, Veronica Seccia, Robert C. Kern, André Coste, Ana R. Sousa, Peter H. Howarth, Victoria S. Benson, Bhabita Mayer, Steve W. Yancey, Robert Chan, Simon B. Gane
Publikováno v:
Allergy: European Journal of Allergy and Clinical Immunology. Wiley-Blackwell
Background: Patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) often require repeat sinus surgery. Mepolizumab reduced the need for sinus surgery in the SYNAPSE trial; this analysis sought to provide a more in-depth assessment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b637855b177b839adc6343aa91256f
https://ueaeprints.uea.ac.uk/id/eprint/86835/
https://ueaeprints.uea.ac.uk/id/eprint/86835/