Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Peter H. Glenister"'
Autor:
Philomena Mburu, Joanne E. Martin, Simon Greenaway, Josephine Peters, Mark A. Strivens, Ian C. Gray, P. Roby, Jean-Louis Guénet, Patrick M. Nolan, Carole D. Nickols, Stéphanie Voegeling, Xue Zhong Liu, R Selley, Adrian M. Isaacs, Stefan L. McCormack, Elizabeth M. C. Fisher, C Thornton, M Browne, Alexandra Erven, Ruth M. Arkell, Tertius Hough, Zuzanna Tymowska-Lalanne, Jackie Hunter, Karen P. Steel, Peter H. Glenister, Kay E. Davies, Rachel E. Hardisty, D Brooker, R Sadri, Nigel K. Spurr, E Whitehill, Lucie Vizor, J A Stevenson, K Pickford, Christine A. Wells, Amy E. Kiernan, M Hewitt, Steve D.M. Brown, Sohaila Rastan, Derek C. Rogers, Caroline Thaung, Jim J. Hagan, R Washbourne, M Nasse
Publikováno v:
Nature Genetics. 25:440-443
As the human genome project approaches completion, the challenge for mammalian geneticists is to develop approaches for the systematic determination of mammalian gene function. Mouse mutagenesis will be a key element of studies of gene function. Phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d69b10742c4b2938bb2e4430adf5d1
https://doi.org/10.1038/78140
https://doi.org/10.1038/78140
Publikováno v:
Mammalian Genome. 10:987-992
Recent advances in the methodologies for cryopreservation of mouse spermatozoa have opened up a number of opportunities for mouse geneticists. We have investigated various applications for this relatively new technology and have explored the potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f3abfefdcc946d1039fc2b9470002c
https://doi.org/10.1007/s003359901145
https://doi.org/10.1007/s003359901145
Autor:
Bruce M. Cattanach, Paul S. Burgoyne, Steven H. Laval, Claire Thornton, Shantha K. Mahadevaiah, Peter H. Glenister, Howard J. Cooke, Carol Rasberry
Publikováno v:
Proceedings of the National Academy of Sciences. 92:10403-10407
We earlier described three lines of sex-reversed XY female mice deleted for sequences believed close to the testes-determining gene (Sry) on the Y chromosome short arm (Yp). The original sex-reversed females appeared among the offspring of XY males t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e99a06e875b332628936aa7da6af3c7
https://doi.org/10.1073/pnas.92.22.10403
https://doi.org/10.1073/pnas.92.22.10403
Autor:
Gavin Kelsey, Jo Peters, Zuzanna Tymowska-Lalanne, Christine M. Williamson, Peter H. Glenister, Antonius Plagge, Martin Fray, Nicola Powles-Glover, Martin R Turner, Wade T. Nottingham, Simon T. Ball, Mark Maconochie
Publikováno v:
Nature genetics. 38(3)
Genomic imprinting results in allele-specific silencing according to parental origin1. Silencing is brought about by imprinting control regions (ICRs) that are differentially marked in gametogenesis2. The group of imprinted transcripts in the mouse G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c696795b9d92070bf6b42c03f3ea935
https://pubmed.ncbi.nlm.nih.gov/16462745
https://pubmed.ncbi.nlm.nih.gov/16462745
Autor:
Josephine Peters, Zuzanna Tymowska-Lalanne, R Selley, Lucie Vizor, M. Bouzyk, Sohaila Rastan, Karen P. Steel, Nigel K. Spurr, Rachel E. Hardisty, A. Kierman, Charlie Reavill, Derek C. Rogers, David P. Kelsell, A. J. Hunter, C Thornton, Simon Greenaway, S. McCormick, Christine A. Wells, Steve D.M. Brown, Tertius Hough, Ian C. Gray, Mark A. Strivens, Joanne E. Martin, Philomena Mburu, Jean-Louis Guénet, I. C. Gray, Steven A. Sheardown, Elizabeth M. C. Fisher, P Nolan, Alexandra Erven, S. Voeling, R Washbourne, Jim J. Hagan, Adrian M. Isaacs, H. Tsai, Kay E. Davies, P. Roby, M Hewitt, Peter H. Glenister
Publikováno v:
Genetica. 122(1)
With the completion of the first draft of the human genome sequence, the next major challenge is assigning function to genes. One approach is genome-wide random chemical mutagenesis, followed by screening for mutant phenotypes of interest and subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec5906b3275e88bb89870e2d9c0bc02
https://pubmed.ncbi.nlm.nih.gov/15619960
https://pubmed.ncbi.nlm.nih.gov/15619960
Autor:
Sian Clements, Elizabeth M. C. Fisher, Sohaila Rastan, Ian C. Gray, Roger D. Cox, A. Jacqueline Hunter, Josephine Peters, Patrick M. Nolan, Joanne E. Martin, Nigel K. Spurr, Peter H. Glenister, Tertius Hough, Vicky Tsipouri, Lee Moir, Mark A. Strivens, Rachael L. Selley, Steve D.M. Brown, Michelle Goldsworthy, A. A. Toye, Lucie Vizor, Stefan L. McCormack, John Wood
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 13(10)
We used ENU mutagenesis in the mouse for the rapid generation of novel mutant phenotypes for both gene function studies and use as new animal models of human disease (Nolan et al. 2000b). One focus of the program was the development of a blood bioche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871c1907b2c2628897f8f49884ba9e3d
https://pubmed.ncbi.nlm.nih.gov/12420138
https://pubmed.ncbi.nlm.nih.gov/12420138
Autor:
Jackie Hunter, Claire Davison, Nicholas J. Parkinson, Steve D.M. Brown, Roger D. Cox, Alison Hugill, Sian Clements, Emma L. Coghill, Peter H. Glenister
Publikováno v:
Nature genetics. 30(3)
The construction of parallel archives of DNA and sperm from mice mutagenized with ethylnitrosurea (ENU) represents a potentially powerful and rapid approach for identifying point mutations in any gene in the mouse genome. We provide support for this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d8fb5debfed7bea96ee6b9aacf9f5d
https://pubmed.ncbi.nlm.nih.gov/11850622
https://pubmed.ncbi.nlm.nih.gov/11850622
Autor:
Peter H. Glenister, Claire Thornton
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 11(7)
Mouse genetics is set to play a pivotal role in the key post-genome challenge-the study of mammalian gene function. Addressing this challenge will involve the development and application of systematic mutagenesis approaches. The expanding mouse mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11a58637974a80c6331bbd86143e169
https://pubmed.ncbi.nlm.nih.gov/10886024
https://pubmed.ncbi.nlm.nih.gov/10886024
Autor:
Rebecca Washbourne, Charlie Reavill, Lucie Vizor, Sohaila Rastan, M Browne, Christine A. Wells, Peter H. Glenister, John Wood, Patrick M. Nolan, Derek C. Rogers, Ian C. Gray, Jackie Hunter, Claire Thornton, Jo Peters, Jim J. Hagan, Mark A. Strivens, Tertius Hough, Elizabeth M. C. Fisher, Nigel K. Spurr, Steve D.M. Brown, JE Martin
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 11(7)
Systematic approaches to mouse mutagenesis will be vital for future studies of gene function. We have begun a major ENU mutagenesis program incorporating a large genome-wide screen for dominant mutations. Progeny of ENU-mutagenized mice are screened
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09383351f86ccc4a30545600752bb68
https://pubmed.ncbi.nlm.nih.gov/10886012
https://pubmed.ncbi.nlm.nih.gov/10886012
