Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Peter H. Ellims"'
Publikováno v:
Scandinavian Journal of Haematology. 30:141-144
The thymidine kinase isoenzyme profile was determined in peripheral blood mononuclear cells and splenic tissue from 4 patients with hairy cell leukaemia, in order to assess the proliferative state of the hairy cell. The predominance of TK1 activity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5459cdce641e7e8851c515d4cae00cad
https://doi.org/10.1111/j.1600-0609.1983.tb01460.x
https://doi.org/10.1111/j.1600-0609.1983.tb01460.x
Publikováno v:
Molecular and Cellular Biochemistry. 57:185-190
Deoxycytidylate deaminase has been highly purified (1232-fold) from human leukemia CCRF-CEM cells. The native molecular weight of the enzyme is 108 000 and subunit molecular weight 50 500, suggesting that the native enzyme exists as a dimer. The enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ce41048cff53cb0c500f9a500f95ab
https://doi.org/10.1007/bf00849195
https://doi.org/10.1007/bf00849195
Autor:
M B Van der Weyden, Peter H. Ellims
Publikováno v:
Journal of Biological Chemistry. 255:11290-11295
Thymidine kinase (EC 2.7.1.21) has been purified 5600-fold to apparent homogeneity from normal adult human liver. The purification included affinity chromatography on a thymidine column. The subunit molecular weight of the enzyme obtained from this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7874b0944448b548c3dc478ebbabaddb
https://doi.org/10.1016/s0021-9258(19)70289-0
https://doi.org/10.1016/s0021-9258(19)70289-0
Publikováno v:
Biochemical and Biophysical Research Communications. 89:103-107
In extracts of peripheral blood lymphocytes of cobalamin or folate deficient patients thymidine kinase activity is increased three fold and exhibits properties of the fetal isoenzyme. Appropriate vitamin therapy results in reduction of this activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c18d2a14d8472ef5de44be294b3d8c
https://doi.org/10.1016/0006-291x(79)90949-5
https://doi.org/10.1016/0006-291x(79)90949-5
Autor:
Brian S. Faragher, Peter H. Ellims, Barry G. Firkin, Maxwell G. Whiteside, Martin B. Weyden, Graeme N. Brodie
Publikováno v:
Cancer. 44:2140-2146
Three patients with drug-induced hypoplastic anemia terminating 2 to 6 years after presentation with erythroleukemia are described. All were treated for prolonged periods with androgen and corticosteroid and two of the patients showed apparent depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfa6b6515ba7479a5cfc1214af3ed5dc
https://doi.org/10.1002/1097-0142(197912)44:6<2140::aid-cncr2820440626>3.0.co
https://doi.org/10.1002/1097-0142(197912)44:6<2140::aid-cncr2820440626>3.0.co
Publikováno v:
British Journal of Haematology. 49:479-481
The profile of thymidine kinase isoenzymes was determined in peripheral blood lymphocytes from 14 patients with chronic lymphocytic leukaemia (CLL) and 31 controls. Twelve patients with indolent disease showed TK2 isoenzyme activity, while two patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18ef909530052a76252db79abbcb65a
https://doi.org/10.1111/j.1365-2141.1981.tb07251.x
https://doi.org/10.1111/j.1365-2141.1981.tb07251.x
Publikováno v:
Acta haematologica. 69(1)
A 16-year-old schoolgirl presented with acute promyelocytic leukemia. 10 days after induction chemotherapy with doxorubicin and cytosine arabinoside together with heparinisation for the accompanying disseminated intravascular coagulopathy, she develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7464f56a41ac342838196bb511c446f
https://pubmed.ncbi.nlm.nih.gov/6401894
https://pubmed.ncbi.nlm.nih.gov/6401894
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 88(1)
A radiometric method is described for measuring pyrimidine 5′-nucleotidase activity in human peripheral blood haemolysate. The substrate [ 14 C]uridine monophosphate is converted to [ 14 C]uridine. Two simple and rapid methods to isolate the produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbadf2a78e84afec68051a6ffc62165e
https://pubmed.ncbi.nlm.nih.gov/679498
https://pubmed.ncbi.nlm.nih.gov/679498
Publikováno v:
Biochimica et biophysica acta. 660(2)
Thymidine kinase (ATP : thymidine 5'-phosphotransferase, EC 2.7.1.21), purified to apparent homogeneity from human liver, was found to have Michaelis constants for thymidine and ATP of 5 and 90 microM, respectively. Based on studies of initial veloci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a2d74f766bdc991af214ab9672307b
https://pubmed.ncbi.nlm.nih.gov/7284401
https://pubmed.ncbi.nlm.nih.gov/7284401
Publikováno v:
American journal of hematology. 14(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f2737f851cfa07eae70cac59ed0b9a
https://pubmed.ncbi.nlm.nih.gov/6303117
https://pubmed.ncbi.nlm.nih.gov/6303117