Výsledky vyhledávání - "Peter H. Boyle"

Akademický článek

Sigmatropic rearrangements of 2,4-dinitrophenyl oximes

Autor: Peter H. Boyle, Haslin Dato Paduka Ali, Thomas J. Mc Donald

Publikováno v: ARKIVOC, Vol 2003, Iss 7, Pp 67-79 (2003)

Externí odkaz: https://doaj.org/article/46f71439271d4e8c9e23d1eeb1e669c3

The synthesis of 7-deazaguanines as potential inhibitors of guanosine triphosphate cyclohydrolase I

Autor: Salvatore La Rosa, Fabien Leurquin, Colin L. Gibson, Alexandra Lemaçon, Colin J. Suckling, Peter H. Boyle, Kyuji Ohta

Publikováno v: Tetrahedron. 60:943-959

Variously substituted 7-deazaguanines are of interest as inhibitors of GTP cyclohydrolase I, the first enzyme in the biosynthetic pathway leading to dihydrofolate and tetrahydrobiopterin. Methods are described for the synthesis of 7-deazaguanines sub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::289c75f2484806eca826131387cb3ba9
https://doi.org/10.1016/j.tet.2003.11.030

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Targeting of photooxidative damage on single-stranded DNA representing the bcr-abl chimeric gene using oligonucleotide-conjugates containing [Ru(phen)3]2+-like photosensitiser groups

Autor: Mark Lawler, R. Jeremy H. Davies, Clare M. O'Keeffe, Yvonne Kavanagh, Peter H. Boyle, Clarke Stevenson, John M. Kelly, Conor W. Crean

Publikováno v: Photochemical & Photobiological Sciences. 1:1024-1033

Photooxidative damage was induced predominantly at a single guanine base in a target DNA by irradiation (lambda > 330 nm) in the presence of complementary oligodeoxynucleotide conjugates (ODN-5'-linker-[Ru(phen)3]2+) (phen = 1,10-phenanthroline). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac1f4ac8265cbf50995a86b7c09afc4
https://doi.org/10.1039/b207387k

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Synthesis of (S)-2-Amino-1,1-diphenylbutan-4-ol; conversion of an α-amino acid into an α-(diphenylmethyl) amine without loss of optical purity

Autor: Gladys D. Hosken, Anthony P. Davis, Peter H. Boyle, Kevin J. Dempsey

Publikováno v: Tetrahedron: Asymmetry. 6:2819-2828

The title amino-alcohol 4 is an intermediate for the preparation of chiral bicyclic amidines and guanidines, and also for polyamines with potential as ligands in enantioselective catalysis. It has been synthesized from (S)-methionine 1 via (S)-homose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a01dd7c3741010640fa4afb25599c2a
https://doi.org/10.1016/0957-4166(95)00373-w

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Diaminomethyleneaminocarbonyldinitromethane, formed during the preparation of 2-amino-6-chloro-5-nitro-4(3H)-pyrimidinone by nitration of 2-amino-6-chloro-4(3H)-pyrimidinone

Autor: Peter H. Boyle, Fabien Leurquin, Karen M Daly, J.Kenneth Robinson, Damien T Scully

Publikováno v: Tetrahedron Letters. 42:1793-1795

Difficulties in the nitration of 2-amino-6-chloro-4(3H)-pyrimidinone to give the widely used heterocyclic precursor 2-amino-6-chloro-5-nitro-4(3H)-pyrimidinone are shown to be due to formation of an unusual open-chain gem-dinitro compound, identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c30953479c9201fcbc12c7be90dcc8b
https://doi.org/10.1016/s0040-4039(00)02360-1

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ChemInform Abstract: Synthesis of a 2,4-Diaminodihydrohomopteridine, 6-Acetyl-2,4-diamino-7, 8-dihydro-9H-pyrimido(4,5-b)(1,4)diazepine, Using a Furazano(3,4-d) pyrimidine Precursor

Autor: H. A. Khattab, E. M. Hughes, Peter H. Boyle

Publikováno v: ChemInform. 22

5-Amino-7-(methylthio)furazano[3,4-d]pyrimidine (3) reacts readily with a variety of amines and hydroxylamines under mild conditions, with the introduction of an N-substituent at position 7. Using this reaction of (3) with 1-amino-4,4-diethoxy-3-pent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3247337f358fcfe93f426bc3864b4dc4
https://doi.org/10.1002/chin.199140234

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Deportonation of nitroalkanes by bicyclic amidine and guanidine bases; evidence for molecular recognition within a catalytic cycle for C–C bond formation

Autor: Anthony P. Davis, Maire A. Convery, Gladys D. Hosken, Brian A. Murray, Peter H. Boyle

Publikováno v: J. Chem. Soc., Chem. Commun.. :239-242

Evidence from 1H NMR spectroscopy supported by X-ray crystallography, suggests that the bicyclic amidine and guanidine bases 2 and 3 react with nitroalkanes in non-polar organic solvents to give tightly-bound ion pairs 5; it is argued that homochiral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b7ef09c27ab6ff5a4a5384b2dd71089
https://doi.org/10.1039/c39920000239

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Synthesis of a 2,4-diaminodihydrohomopteridine, 6-acetyl-2,4-diamino-7,8-dihydro-9H-pyrimido[4,5-b][1,4]diazepine, using a furazano[3,4-d]pyrimidine precursor

Autor: H. A. Khattab, E. M. Hughes, Peter H. Boyle

Publikováno v: Tetrahedron. 47:5259-5268

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14ceac812239807bdf334763a3b7b460
https://doi.org/10.1016/s0040-4020(01)87137-4

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