Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Peter H M, Hoet"'
Autor:
Buket Bakan, Anne-Charlotte Jonckheere, Tatjana Decaesteker, Nora F. Marain, Sivakumar Murugadoss, Nefise Ulku Karabay Yavasoglu, Umut Şahar, Raziye Hilal Şenay, Sinan Akgöl, Özlem Göksel, Peter H. M. Hoet, Jeroen A. J. Vanoirbeek
Publikováno v:
Toxics, Vol 11, Iss 12, p 974 (2023)
The implementation of nanotechnology in pulmonary delivery systems might result in better and more specific therapy. Therefore, a nano-sized drug carrier should be toxicologically inert and not induce adverse effects. We aimed to investigate the resp
Externí odkaz:
https://doaj.org/article/c215a109da2b48d0a31042d84771bff8
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Autoimmunity can result from the interplay between genetic background and effects of environmental and/or occupational exposure to hazardous materials. Several compounds, including silica dust, have been linked with systemic autoi
Externí odkaz:
https://doaj.org/article/720d1a4366974b1793018178d2d41f89
Autor:
Steven Ronsmans, Jolien De Ridder, Eline Vandebroek, Stephan Keirsbilck, Benoit Nemery, Peter H. M. Hoet, Steven Vanderschueren, Wim A. Wuyts, Jonas Yserbyt
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Sarcoidosis most commonly affects lungs and intrathoracic lymph nodes, but any other organ can be involved. In epidemiological studies, many occupational and environmental exposures have been linked to sarcoidosis but their relati
Externí odkaz:
https://doaj.org/article/955afc69d414469e9d84fb2f4459174f
Publikováno v:
Cells, Vol 11, Iss 5, p 864 (2022)
The process of granuloma formation is complex, and due to species differences, the validity of animal studies is somewhat questioned. Moreover, the large number of animals needed to observe the different stages of development also raises ethical ques
Externí odkaz:
https://doaj.org/article/735df3b1f1cb44ec8dd94d474457aac6
Autor:
Yeranddy A. Alpizar, Brett Boonen, Alicia Sanchez, Carole Jung, Alejandro López-Requena, Robbe Naert, Brecht Steelant, Katrien Luyts, Cristina Plata, Vanessa De Vooght, Jeroen A. J. Vanoirbeek, Victor M. Meseguer, Thomas Voets, Julio L. Alvarez, Peter W. Hellings, Peter H. M. Hoet, Benoit Nemery, Miguel A. Valverde, Karel Talavera
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
LPS is a major component of gram-negative bacterial cell walls, and triggers immune responses in airway epithelium by activating TLR4. Here the authors show that LPS also activates TRPV4, thereby inducing fast defense responses such as nitric oxide p
Externí odkaz:
https://doaj.org/article/305c11c87f63412e9d5471df82642beb
Publikováno v:
Nanomaterials, Vol 11, Iss 5, p 1283 (2021)
Via inhalation we are continuously exposed to environmental and occupational irritants which can induce adverse health effects, such as irritant-induced asthma (IIA). The airway epithelium forms the first barrier encountered by these agents. We inves
Externí odkaz:
https://doaj.org/article/03932e48a8ed4e319f3a1f82b25c3b88
Autor:
Fien C Devos, Lore Pollaris, Jonathan Cremer, Sven Seys, Tomoaki Hoshino, Jan Ceuppens, Karel Talavera, Benoit Nemery, Peter H M Hoet, Jeroen A J Vanoirbeek
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180690 (2017)
While the importance of the Th2 cytokine IL-13 as a central mediator of airway hyperreactivity (AHR) has been described in allergic protein-induced asthma, this has never been investigated in chemical-induced asthma.We examined the importance of IL-1
Externí odkaz:
https://doaj.org/article/fdb01a8dd6c34b7592c8a3c8f05011c2
Autor:
Steven, Ronsmans, Pieter, Goeminne, Naïm, Jerjir, Vicky, Nowé, Eline, Vandebroek, Stephan, Keirsbilck, Birgit, Weynand, Peter H M, Hoet, Jeroen A J, Vanoirbeek, Wim A, Wuyts, Jonas, Yserbyt, Benoit, Nemery
Publikováno v:
Chest. 162(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1e406a848bfd9828c515c5411eebbd8
https://pubmed.ncbi.nlm.nih.gov/35381260
https://pubmed.ncbi.nlm.nih.gov/35381260
Publikováno v:
Archives of toxicology. 96(5)
Systemic exposure to nanoparticles (NPs) adversely affects different organs, including the nervous system. We systematically extracted data from publication on PubMed and Embase database up to the year 2020, and analyzed in vitro and in vivo neurotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f040693fad9a223fccaa14bef2200400
https://pubmed.ncbi.nlm.nih.gov/35278105
https://pubmed.ncbi.nlm.nih.gov/35278105
Autor:
Steven Haenen, Jeroen A J Vanoirbeek, Vanessa De Vooght, Liliane Schoofs, Benoit Nemery, Elke Clynen, Peter H M Hoet
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138791 (2015)
The role of B-lymphocytes in chemical-induced asthma is largely unknown. Recent work demonstrated that transferring B lymphocytes from toluene diisocyanate (TDI)-sensitized mice into naïve mice, B cell KO mice and SCID mice, triggered an asthma-like
Externí odkaz:
https://doaj.org/article/f04745754389477aa5cf1fba856b273b