Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Peter H L Krijger"'
Autor:
Ayal Hendel, Peter H L Krijger, Noam Diamant, Zohar Goren, Petra Langerak, Jungmin Kim, Thomas Reissner, Kyoo-young Lee, Nicholas E Geacintov, Thomas Carell, Kyungjae Myung, Satoshi Tateishi, Alan D'Andrea, Heinz Jacobs, Zvi Livneh
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002262 (2011)
Translesion DNA synthesis (TLS) is a DNA damage tolerance mechanism in which specialized low-fidelity DNA polymerases bypass replication-blocking lesions, and it is usually associated with mutagenesis. In Saccharomyces cerevisiae a key event in TLS i
Externí odkaz:
https://doaj.org/article/bd8b7458253a4fe6ac0abb4029cfcd8a
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16669 (2011)
Monoubiquitylation of the homotrimeric DNA sliding clamp PCNA at lysine residue 164 (PCNA(K164)) is a highly conserved, DNA damage-inducible process that is mediated by the E2/E3 complex Rad6/Rad18. This ubiquitylation event recruits translesion synt
Externí odkaz:
https://doaj.org/article/3c5f9de1d9ff406ea01c6051fdb4296c
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15236 (2010)
To generate high affinity antibodies during an immune response, B cells undergo somatic hypermutation (SHM) of their immunoglobulin genes. Error-prone translesion synthesis (TLS) DNA polymerases have been reported to be responsible for all mutations
Externí odkaz:
https://doaj.org/article/d2e77dad11a5417ab2ff7bdcb316ff15
Autor:
Clément Rouillon, Bruna V Eckhardt, Leonie Kollenstart, Fabian Gruss, Alexander E E Verkennis, Inge Rondeel, Peter H L Krijger, Giulia Ricci, Alva Biran, Theo van Laar, Charlotte M Delvaux de Fenffe, Georgiana Luppens, Pascal Albanese, Koichi Sato, Richard A Scheltema, Wouter de Laat, Puck Knipscheer, Nynke H Dekker, Anja Groth, Francesca Mattiroli
Publikováno v:
Nucleic acids research, 51(8)
During every cell cycle, both the genome and the associated chromatin must be accurately replicated. Chromatin Assembly Factor-1 (CAF-1) is a key regulator of chromatin replication, but how CAF-1 functions in relation to the DNA replication machinery
Autor:
Niels J. Rinzema, Konstantinos Sofiadis, Sjoerd J. D. Tjalsma, Marjon J. A. M. Verstegen, Yuva Oz, Christian Valdes-Quezada, Anna-Karina Felder, Teodora Filipovska, Stefan van der Elst, Zaria de Andrade dos Ramos, Ruiqi Han, Peter H. L. Krijger, Wouter de Laat
Publikováno v:
Nature Structural & Molecular Biology, 29(6), 563-574. Nature Publishing Group
Developmental gene expression is often controlled by distal regulatory DNA elements called enhancers. Distant enhancer action is restricted to structural chromosomal domains that are flanked by CTCF-associated boundaries and formed through cohesin ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cd2cc4773e8b4dbb0a1e6367bd7058
https://pure.knaw.nl/portal/en/publications/d8e1f888-d14c-4139-a769-885db924b103
https://pure.knaw.nl/portal/en/publications/d8e1f888-d14c-4139-a769-885db924b103
Autor:
Maxime Bellefroid, Anthony Rodari, Mathilde Galais, Peter H L Krijger, Sjoerd J D Tjalsma, Lorena Nestola, Estelle Plant, Erica S M Vos, Sara Cristinelli, Benoit Van Driessche, Caroline Vanhulle, Amina Ait-Ammar, Arsène Burny, Angela Ciuffi, Wouter de Laat, Carine Van Lint
Publikováno v:
Nucleic Acids Research, 50(6), 3190-3202. Oxford University Press
Bovine leukemia virus (BLV)-induced tumoral development is a multifactorial phenomenon that remains incompletely understood. Here, we highlight the critical role of the cellular CCCTC-binding factor (CTCF) both in the regulation of BLV transcriptiona
Autor:
Peter H L Krijger, Tim A Hoek, Sanne Boersma, Lieke I P M Donders, Maaike M C Broeders, Mark Pieterse, Pim W Toonen, Ive Logister, Bram M P Verhagen, Marjon J A M Verstegen, Thomas W van Ravesteyn, Rene J T M Roymans, Francesca Mattiroli, Jo Vandesompele, Monique Nijhuis, Stefan Meijer, Anton van Weert, Edwin Dekker, Fred J Dom, Rob Ruijtenbeek, Lieven B J van der Velden, Jeroen H B van de Bovenkamp, Martijn Bosch, Wouter de Laat, Marvin E Tanenbaum
An in-house multiplex RT-qPCR , targeting SARS-CoV-2and PDV as internal control [1][2], developed on QuantStudio 7 Pro Real-Time PCR Systems using Life Technologies Taqman FastVirus 1-step mastermix with E-gene primers and probe as described by Corma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::606620bc45663e98f4a165e3c5597363
https://doi.org/10.17504/protocols.io.bxmjpk4n
https://doi.org/10.17504/protocols.io.bxmjpk4n
Autor:
Peter H L Krijger, Tim A Hoek, Sanne Boersma, Lieke I P M Donders, Maaike M C Broeders, Mark Pieterse, Pim W Toonen, Ive Logister, Bram M P Verhagen, Marjon J A M Verstegen, Thomas W van Ravesteyn, Rene J T M Roymans, Francesca Mattiroli, Jo Vandesompele, Monique Nijhuis, Stefan Meijer, Anton van Weert, Edwin Dekker, Fred J Dom, Rob Ruijtenbeek, Lieven B J van der Velden, Jeroen H B van de Bovenkamp, Martijn Bosch, Wouter de Laat, Marvin E Tanenbaum
STRIP is a start-to-end streamlined and automated procedure for COVID-19 testing, centering on a single Tecan Fluent liquid-handling robot that can process over 14,000 samples per day. The sensitivity, specificity, and practical implementation of STR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c203b8159b49cfd50739c96f7f0bc9f
https://doi.org/10.17504/protocols.io.bxiwpkfe
https://doi.org/10.17504/protocols.io.bxiwpkfe
Autor:
Peter H L Krijger, Tim A Hoek, Sanne Boersma, Lieke I P M Donders, Maaike M C Broeders, Mark Pieterse, Pim W Toonen, Ive Logister, Bram M P Verhagen, Marjon J A M Verstegen, Thomas W van Ravesteyn, Rene J T M Roymans, Francesca Mattiroli, Jo Vandesompele, Monique Nijhuis, Stefan Meijer, Anton van Weert, Edwin Dekker, Fred J Dom, Rob Ruijtenbeek, Lieven B J van der Velden, Jeroen H B van de Bovenkamp, Martijn Bosch, Wouter de Laat, Marvin E Tanenbaum
STRIP is a start-to-end streamlined and automated procedure for COVID-19 testing, centering on a single Tecan Fluent liquid-handling robot that can process over 14,000 samples per day. Here we describe the protocol to prepare the magnetic beads that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc785f05901788edbf0d2fa39f1858e3
https://doi.org/10.17504/protocols.io.bxixpkfn
https://doi.org/10.17504/protocols.io.bxixpkfn
Autor:
Peter H L Krijger, Tim A Hoek, Sanne Boersma, Lieke I P M Donders, Maaike M C Broeders, Mark Pieterse, Pim W Toonen, Ive Logister, Bram M P Verhagen, Marjon J A M Verstegen, Thomas W van Ravesteyn, Rene J T M Roymans, Francesca Mattiroli, Jo Vandesompele, Monique Nijhuis, Stefan Meijer, Anton van Weert, Edwin Dekker, Fred J Dom, Rob Ruijtenbeek, Lieven B J van der Velden, Jeroen H B van de Bovenkamp, Martijn Bosch, Wouter de Laat, Marvin E Tanenbaum
One of the most critical innovations within STRIP is the collection of samples in small tubes (0.8 ml compared with 5–15 ml in standard diagnostics) with virus-inactivating and RNA-stabilizing lysis buffer (InActiv Blue) spiked with a control RNA (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::987d5fcd0a17bbdc3447218f41b4e1f8
https://doi.org/10.17504/protocols.io.buvenw3e
https://doi.org/10.17504/protocols.io.buvenw3e