Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Peter Grundt"'
Autor:
Ashli M. Tucker, Peter Grundt
Publikováno v:
ARKIVOC, Vol 2012, Iss 1, Pp 546-569 (2012)
Externí odkaz:
https://doaj.org/article/e01fa899489d44a7a3ebc940efba2dae
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 10, Pp o2695-o2696 (2011)
The chiral title compound, C21H20N4O2, crystallizes as a racemic mixture. In the crystal, molecules form centrosymmetric π-overlapping dimers [interplanar distance = 3.338 (6) Å], which are further connected along the a axis forming centrosymmetric
Externí odkaz:
https://doaj.org/article/fd1bbe2d5b904d9abc0038e7569a7616
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 10, Pp o2585-o2586 (2010)
In the title compound (systematic name: 9-ethoxy-10-methoxy-5,6-dihydro-1,3-dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium iodide monohydrate), 2C21H20NO4+·2I−·H2O, two independent molecules pack in the unit cell, where interactions between t
Externí odkaz:
https://doaj.org/article/40eef9658d424609b565a90cffade61f
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 6, Pp o1474-o1475 (2010)
There are two independent molecules in the asymmetric unit of the title compound, C15H6Cl2N2O2. The conjugated four-ring system is essentially planar in each molecule [maximum deviation = 0.089 (2) Å]. In the crystal, weak intermolecular C—H...Cl,
Externí odkaz:
https://doaj.org/article/75661903c72f433185a63db01db5044f
Autor:
Ming Xu, Andrew C. Barrett, Morgane Thomsen, Peter Grundt, Amy Hauck Newman, S. Barak Caine, Paul Butler, Gregory T. Collins
Publikováno v:
Experimental and Clinical Psychopharmacology. 20:352-363
The dopamine D3 receptor has received attention over the last two decades as a target for medications development for substance abuse disorders. Results have remained mixed. Despite emergence of more D3-selective ligands, possible attribution of obse
Autor:
Robin J. Tyacke, Emma S J Robinson, Alan L. Hudson, Amy Fisher, David J. Nutt, Stephen M. Husbands, Peter Grundt, Christine A. Parker, Emma M. Turner
Publikováno v:
Synapse. 66:542-551
The density of the Imidazoline2 binding site (I2BS) has been shown to change in psychiatric conditions such as depression and addiction, along with neurodegenerative disorders such as Alzheimer's disease and Huntington's chorea. The presence of I2BS
Autor:
Brandi L. Blaylock, Robert W. Gould, Michael A. Nader, Robert T. Luedtke, A. Banala, Peter Grundt, Amy Hauck Newman
Publikováno v:
Neuropsychopharmacology. 36:1104-1113
Although dopamine D(3) receptors have been associated with cocaine abuse, little is known about the consequences of chronic cocaine on functional activity of D(3) receptor-preferring compounds. This study examined the behavioral effects of D(3) recep
Autor:
Peter Grundt, Joseph B. Mandeville, Amy Hauck Newman, Bruce G. Jenkins, Y. Iris Chen, Ji-Kyung Choi, Susanta K. Sarkar
Publikováno v:
Psychopharmacology. 212:59-72
Dopamine D3 receptors (D3R) may be important therapeutic targets for both drug abuse and dyskinesias in Parkinson’s disease; however, little is known about their functional circuitry. We wished to determine if D3R antagonists SB-277011 and PG-01037
Autor:
James Henry Woods, David K. Grandy, Peter Grundt, Ming Xu, Jonathan L. Katz, Noel M. Paul, Gregory T. Collins, Amy Hauck Newman, Su Min Li
Publikováno v:
Behavioural Pharmacology. 21:171-181
Dopaminergic (DA) agonist-induced yawning in rats seems to be mediated by DA D3 receptors, and low doses of several DA agonists decrease locomotor activity, an effect attributed to presynaptic D2 receptors. Effects of several DA agonists on yawning a
Publikováno v:
Tetrahedron Letters. 54:6804-6806
Tryptanthrin is a natural product with numerous important pharmacological properties. Tryptanthrin and its analogs are commonly prepared by condensation of isatoic anhydride and isatin. In this Letter we investigate the formation of tryptanthrin deri