Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Peter Greimel"'
Autor:
Hiroya Naruse, Hiroyuki Ishiura, Kayoko Esaki, Jun Mitsui, Wataru Satake, Peter Greimel, Nanoka Shingai, Yuka Machino, Yasumasa Kokubo, Hirotoshi Hamaguchi, Tetsuya Oda, Tomoko Ikkaku, Ichiro Yokota, Yuji Takahashi, Yuta Suzuki, Takashi Matsukawa, Jun Goto, Kishin Koh, Yoshihisa Takiyama, Shinichi Morishita, Takeo Yoshikawa, Shoji Tsuji, Tatsushi Toda
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 4, Pp 946-957 (2024)
Abstract Objective Amyotrophic lateral sclerosis (ALS) is a devastating, incurable neurodegenerative disease. A subset of ALS patients manifests with early‐onset and complex clinical phenotypes. We aimed to elucidate the genetic basis of these case
Externí odkaz:
https://doaj.org/article/a933b528a8fe470791e3994a6a0b880c
Autor:
Yumiko Uchida, Yukihiro Takahashi, Chikara Kurata, Yukihiro Morimoto, Eishin Ohtani, Asako Tosaki, Akiko Kumagai, Peter Greimel, Toshiya Nishikubo, Atsushi Miyawaki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract Phototherapy converts lipophilic unconjugated bilirubin to hydrophilic bilirubin photoisomers, such as lumirubin. We comparatively used a blue light-emitting diode (LED) and a green fluorescent lamp (FL) as light sources for phototherapy of
Externí odkaz:
https://doaj.org/article/bdffe23263f54b3292751ec0464aa1f5
Autor:
Yumiko Uchida, Yukihiro Takahashi, Yukihiro Morimoto, Peter Greimel, Asako Tosaki, Akiko Kumagai, Toshiya Nishikubo, Atsushi Miyawaki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Lumirubin is the most prevalently excreted hydrophilic bilirubin photoisomer in phototherapy for neonatal jaundice caused by excess hydrophobic unconjugated bilirubin (ZZ-bilirubin). We developed a simple method to estimate the amount of lum
Externí odkaz:
https://doaj.org/article/7138e2d6069a45848503ae995c4fefbb
Autor:
Lindsey T. Lelieveld, Mina Mirzaian, Chi-Lin Kuo, Marta Artola, Maria J. Ferraz, Remco E.A. Peter, Hisako Akiyama, Peter Greimel, Richard J.B.H.N. van den Berg, Herman S. Overkleeft, Rolf G. Boot, Annemarie H. Meijer, Johannes M.F.G. Aerts
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 11, Pp 1851-1867 (2019)
μ-glucosidases [GBA1 (glucocerebrosidase) and GBA2] are ubiquitous essential enzymes. Lysosomal GBA1 and cytosol-facing GBA2 degrade glucosylceramide (GlcCer); GBA1 deficiency causes Gaucher disease, a lysosomal storage disorder characterized by lys
Externí odkaz:
https://doaj.org/article/05ce0c35bb594489bd17fa37e18c9942
GPRC5B-Mediated Sphingomyelin Synthase 2 Phosphorylation Plays a Critical Role in Insulin Resistance
Publikováno v:
iScience, Vol 8, Iss , Pp 250-266 (2018)
Summary: GPRC5B recruitment of Src family kinases has been implicated in diet-induced insulin resistance. However, the mechanism of this action is not fully understood. Here, we report that GPRC5B-mediated phosphorylation of sphingomyelin synthase 2
Externí odkaz:
https://doaj.org/article/aa23a58beea34d0dacb5a3dc78231d00
Autor:
Mariko Sumi, Asami Makino, Takehiko Inaba, Yasushi Sako, Fumihiro Fujimori, Peter Greimel, Toshihide Kobayashi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract We have developed and characterized a novel photoswitchable phospholipid analog termed N-nitroBIPS-DPPG. The fluorescence can be switched on and off repeatedly with minimal photobleaching by UV or visible light exposure, respectively. The ra
Externí odkaz:
https://doaj.org/article/d582f709b1b3429a9a380e5bb0e37308
Autor:
Hisako Akiyama, Kazuki Nakajima, Yoshiyuki Itoh, Tomoko Sayano, Yoko Ohashi, Yoshiki Yamaguchi, Peter Greimel, Yoshio Hirabayashi
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 11, Pp 2061-2072 (2016)
To date, sterylglucosides have been reported to be present in various fungi, plants, and animals. In bacteria, such as Helicobacter pylori, proton NMR spectral analysis of isolated 1-O-cholesteryl-β-d-glucopyranoside (GlcChol) demonstrated the prese
Externí odkaz:
https://doaj.org/article/40d0c6e1f2444cbda84027b8dfcb831c
Autor:
Hema Balakrishna Bhat, Takuma Kishimoto, Mitsuhiro Abe, Asami Makino, Takehiko Inaba, Motohide Murate, Naoshi Dohmae, Atsushi Kurahashi, Kozo Nishibori, Fumihiro Fujimori, Peter Greimel, Reiko Ishitsuka, Toshihide Kobayashi
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2933-2943 (2013)
A mixture of sphingomyelin (SM) and cholesterol (Chol) exhibits a characteristic lipid raft domain of the cell membranes that provides a platform to which various signal molecules as well as virus and bacterial proteins are recruited. Several protein
Externí odkaz:
https://doaj.org/article/a052151917524820855157df559a10a8
Autor:
Koki Kano, Nozomi Ishii, Atsushi Miyagawa, Hiroaki Takeda, Yoshio Hirabayashi, Hiroyuki Kamiguchi, Peter Greimel, Ichiro Matsuo
Publikováno v:
Organic & Biomolecular Chemistry. 21:2138-2142
Convenient one-pot synthesis of anomeric glycosyl phosphates by direct condensation of unprotected glucose with phospholipid derivatives in aqueous media while retaining high levels of stereoselective control.
Autor:
Darcy Lacanilao Garza, Shinya Hanashima, Yuichi Umegawa, Michio Murata, Masanao Kinoshita, Nobuaki Matsumori, Peter Greimel
Publikováno v:
Langmuir. 38:10478-10491
The ginsenoside Rh2 (Rh2) is a saponin of medicinal ginseng, and it has attracted much attention for its pharmacological activities. In this study, we investigated the interaction of Rh2 with biological membranes using model membranes. We examined th