Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Peter Glunz"'
Publikováno v:
CHIMIA, Vol 51, Iss 1-2 (1997)
With the intent of discovering novel molecular scaffolds for designing protease inhibitors, the computer program GrowMol was used to generate peptidemimetic inhibitors of aspartic proteases. Beginning with the X-ray crystal structure of A66702 comple
Externí odkaz:
https://doaj.org/article/78683646fd3947d791a37659bd40fd37
Publikováno v:
Rational Drug Design ISBN: 9781461271598
The conceptual basis for structure-based drug design was formulated 100 years ago by Emil Fisher(1). His “lock and key” hypothesis is a constantly recurring theme in modern drug design. Previously, knowledge of the “lock”, i.e. the biochemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edda4e35289f436c4e3bdb507ff6b4b4
https://doi.org/10.1007/978-1-4612-1480-9_9
https://doi.org/10.1007/978-1-4612-1480-9_9