Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Peter Gargalovic"'
Autor:
Corina J.A. Moen, Aart P. Tholens, Peter J. Voshol, Willeke de Haan, Louis M. Havekes, Peter Gargalovic, Aldons J. Lusis, Ko Willems van Dȳk, Rune R. Frants, Marten H. Hofker, Patrick C.N. Rensen
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 10, Pp 2182-2192 (2007)
The Hyplip2 congenic mouse strain contains part of chromosome 15 from MRL/MpJ on the BALB/cJ background. Hyplip2 mice show increased plasma levels of cholesterol and predominantly triglycerides (TGs) and are susceptible to diet-induced atherosclerosi
Externí odkaz:
https://doaj.org/article/0b85f06617064831b97c73353612aa91
Autor:
Lawrence W. Castellani, Peter Gargalovic, Maria Febbraio, Sarada Charugundla, Ming-Len Jien, Aldons J. Lusis
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2377-2387 (2004)
We previously demonstrated that transgenic mice overexpressing mouse apolipoprotein A-II (apoA-II) exhibit several traits associated with the insulin resistance (IR) syndrome, including increased atherosclerosis, hypertriglyceridemia, obesity, and IR
Externí odkaz:
https://doaj.org/article/390913d425e547d0800bc73392a84ee9
Autor:
Peter Gargalovic, Ladislav Dory
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 9, Pp 1622-1632 (2003)
Macrophage apoptosis is an important factor in determining the efficiency of the immune response, atherosclerotic lesion stability, and clearance of aged cells by phagocytosis. The involvement of caveolin-1 in the regulation of apoptosis has been pre
Externí odkaz:
https://doaj.org/article/f214c116a4974b28a5f6eda8a9af6598
Autor:
Peter Gargalovic, Ladislav Dory
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 1, Pp 11-21 (2003)
The identification of caveolin-1 more than a decade ago initiated active research into its role in the formation of caveolae, membrane trafficking, signal transduction pathways, and lipid homeostasis. Although caveolins are ubiquitously expressed, th
Externí odkaz:
https://doaj.org/article/8b2752c687554ba297f1a91b26dd277e
Autor:
Anatole Ghazalpour, Brian Bennett, Vladislav A Petyuk, Luz Orozco, Raffi Hagopian, Imran N Mungrue, Charles R Farber, Janet Sinsheimer, Hyun M Kang, Nicholas Furlotte, Christopher C Park, Ping-Zi Wen, Heather Brewer, Karl Weitz, David G Camp, Calvin Pan, Roumyana Yordanova, Isaac Neuhaus, Charles Tilford, Nathan Siemers, Peter Gargalovic, Eleazar Eskin, Todd Kirchgessner, Desmond J Smith, Richard D Smith, Aldons J Lusis
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1001393 (2011)
The relationships between the levels of transcripts and the levels of the proteins they encode have not been examined comprehensively in mammals, although previous work in plants and yeast suggest a surprisingly modest correlation. We have examined t
Externí odkaz:
https://doaj.org/article/63664e45601942ab95c1f5cacfda19f8
Autor:
Jeremy M. Richter, J. Alex Bates, Peter Gargalovic, Joelle M. Onorato, Claudia Generaux, Tao Wang, David A. Gordon, Ruth R. Wexler, Heather J. Finlay
Publikováno v:
Bioorganicmedicinal chemistry letters. 73
Agonism of the apelin receptor (APJ) has demonstrated beneficial effects in models of heart failure. We have previously disclosed compounds such as 4, which showed good APJ agonist activity but were metabolized to the mono-demethylated, non-interconv
Autor:
Joelle M, Onorato, Carrie, Xu, Xue-Qing, Chen, Anne V, Rose, Claudia, Generaux, Kimberley, Lentz, Petia, Shipkova, Susan, Arthur, James K, Hennan, Roy, Haskell, Michael C, Myers, R Michael, Lawrence, Heather J, Finlay, Michael, Basso, Jeffrey, Bostwick, Gayani, Fernando, Ricardo, Garcia, Samuel, Hellings, Mei-Yin, Hsu, Rongan, Zhang, Lei, Zhao, Peter, Gargalovic
Publikováno v:
Analytical biochemistry. 568
Apelin, the endogenous ligand for the APJ receptor, has generated interest due to its beneficial effects on the cardiovascular system. Synthesized as a 77 amino acid preproprotein, apelin is post-translationally cleaved to a series of shorter peptide
Autor:
Ladislav Dory, Peter Gargalovic
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 1, Pp 11-21 (2003)
The identification of caveolin-1 more than a decade ago initiated active research into its role in the formation of caveolae, membrane trafficking, signal transduction pathways, and lipid homeostasis. Although caveolins are ubiquitously expressed, th
Autor:
Ladislav Dory, Peter Gargalovic
Publikováno v:
Journal of Biological Chemistry. 276:26164-26170
Evidence for caveolin expression in macrophages is scarce and conflicting. We therefore examined caveolin-1 and caveolin-2 expression in resident and thioglycollate-elicited mouse peritoneal macrophages (tg-MPM) and in the J774 mouse macrophage cell