Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Peter Gaede"'
Autor:
Annemie S. Bojer, Martin H. Sørensen, Stine H. Madsen, David A. Broadbent, Sven Plein, Peter Gæde, Per L. Madsen
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Patients with diabetes demonstrate early left ventricular systolic dysfunction. Notably reduced global longitudinal strain (GLS) is related to poor outcomes, the underlying pathophysiology is however still not clearly understood.
Externí odkaz:
https://doaj.org/article/ebd4d56d8bcf4ebea0f85c23c522ff7f
Autor:
Per Lav Madsen, Casper Sejersen, Michael Nyberg, Martin Heyn Sørensen, Ylva Hellsten, Peter Gaede, Annemie Stege Bojer
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The significant morbidity and premature mortality of type 2 diabetes mellitus (T2DM) is largely associated with its cardiovascular consequences. Focus has long been on the arterial atheromatosis of DM giving rise to early stroke and myocardial infarc
Externí odkaz:
https://doaj.org/article/3c164a5efb1040319e3b76a208510bd2
Autor:
Annemie S. Bojer, Martin H. Sørensen, Stine H. Madsen, David A. Broadbent, Sven Plein, Peter Gæde, Per L. Madsen
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Diffuse myocardial fibrosis and microvascular dysfunction are suggested to underlie cardiac dysfunction in patients with type 2 diabetes, but studies investigating their relative impact are lacking. We aimed to study imaging bioma
Externí odkaz:
https://doaj.org/article/a617f8c4784640e6ba2313eb4c269bb9
Autor:
Annemie Stege Bojer, Martin Heyn Sørensen, Niels Vejlstrup, Jens P. Goetze, Peter Gæde, Per Lav Madsen
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background Cardiovascular magnetic resonance imaging (CMR) have described localised non-ischemic late gadolinium enhancement (LGE) lesions of prognostic importance in various non-ischemic cardiomyopathies. Ischemic LGE lesions are prevalent
Externí odkaz:
https://doaj.org/article/4adca82dd4744feea3093f9ff1da01a0
Autor:
Martin H. Sørensen, Annemie S. Bojer, Niklas R. Jørgensen, David A. Broadbent, Sven Plein, Per L. Madsen, Peter Gæde
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background The biomarker fibroblast growth factor-23 (FGF-23) has been associated with increased cardiovascular morbidity and mortality in both patients with and without type 2 diabetes. The aim of this study was to evaluate the relationship
Externí odkaz:
https://doaj.org/article/86aec9dac0f64f5785467c52347615ce
Autor:
Mikkel Jürgens, Morten Schou, Philip Hasbak, Andreas Kjær, Emil Wolsk, Bo Zerahn, Mikkel Wiberg, Niels H. Brandt‐Jacobsen, Peter Gæde, Peter Rossing, Jens Faber, Silvio E. Inzucchi, Finn Gustafsson, Caroline Kistorp
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 15 (2021)
Background Sodium–glucose cotransporter 2 inhibitors reduce hospitalizations for heart failure and cardiovascular death, although the underlying mechanisms have not been resolved. The SIMPLE trial (The Effects of Empagliflozin on Myocardial Flow Re
Externí odkaz:
https://doaj.org/article/3ba59089751549b99cc8b37f185f5f8c
Autor:
Signe Abitz Winther, Jens Christian Øllgaard, Tine Willum Hansen, Bernt Johan von Scholten, Henrik Reinhard, Tarunveer Singh Ahluwalia, Zeneng Wang, Peter Gæde, Hans-Henrik Parving, Stanley Hazen, Oluf Pedersen, Peter Rossing
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0244402 (2021)
AimsThe trimethylamine N-oxide (TMAO) pathway is related to intestinal microbiota and has been associated to risk of cardiovascular disease (CVD). We investigated associations between four plasma metabolites in the TMAO pathway and risk of all-cause
Externí odkaz:
https://doaj.org/article/3494bd01451f42f3801d904bcaecb2ed
Publikováno v:
Diagnostics, Vol 11, Iss 7, p 1282 (2021)
Purpose: In recent years, cardiac magnetic resonance (CMR) has been used to assess LV diastolic function. In this systematic review, studies were identified where CMR parameters had been evaluated in healthy and/or patient groups with proven diastoli
Externí odkaz:
https://doaj.org/article/ac96d1a221cb4cf9973b6bc84f7ba493
Autor:
Shiro Maeda, Masa-aki Kobayashi, Shin-ichi Araki, Tetsuya Babazono, Barry I Freedman, Meredith A Bostrom, Jessica N Cooke, Masao Toyoda, Tomoya Umezono, Lise Tarnow, Torben Hansen, Peter Gaede, Anders Jorsal, Daniel P K Ng, Minoru Ikeda, Toru Yanagimoto, Tatsuhiko Tsunoda, Hiroyuki Unoki, Koichi Kawai, Masahito Imanishi, Daisuke Suzuki, Hyoung Doo Shin, Kyong Soo Park, Atsunori Kashiwagi, Yasuhiko Iwamoto, Kohei Kaku, Ryuzo Kawamori, Hans-Henrik Parving, Donald W Bowden, Oluf Pedersen, Yusuke Nakamura
Publikováno v:
PLoS Genetics, Vol 6, Iss 2, p e1000842 (2010)
It has been suggested that genetic susceptibility plays an important role in the pathogenesis of diabetic nephropathy. A large-scale genotyping analysis of gene-based single nucleotide polymorphisms (SNPs) in Japanese patients with type 2 diabetes id
Externí odkaz:
https://doaj.org/article/351019a1b8e447ccb64a66a67903a95b
Autor:
Niels H. Brandt‐Jacobsen, Mikkel Jürgens, Philip Hasbak, Peter Gæde, Peter Rossing, Jon J. Rasmussen, Camillla Fuchs Andersen, Julie L. Forman, Jens Faber, Silvio E. Inzucchi, Finn Gustafsson, Morten Schou, Caroline Kistorp
Publikováno v:
Brandt-Jacobsen, N H, Jurgens, M, Hasbak, P, Gaede, P, Rossing, P, Rasmussen, J J, Andersen, C F, Forman, J L, Faber, J, Inzucchi, S E, Gustafsson, F, Schou, M & Kistorp, C 2023, ' Reduction of cardiac adipose tissue volume with short-term empagliflozin treatment in patients with type 2 diabetes : A substudy from the SIMPLE randomized clinical trial ', Diabetes, Obesity and Metabolism, vol. 25, no. 3, pp. 844-855 . https://doi.org/10.1111/dom.14933
ObjectiveEctopic accumulation of cardiac adipose tissue volume (CAT) has been associated with cardiac remodelling and cardiac dysfunction in type 2 diabetes and may be a future therapeutic target. In this substudy from the SIMPLE-trial, we investigat