Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Peter G. Chandler"'
Autor:
Meri Ayurini, Peter G. Chandler, Paul D. O’Leary, Ruoxin Wang, David Rudd, Karen D. Milewska, Lara R. Malins, Ashley M. Buckle, Joel F. Hooper
Publikováno v:
JACS Au, Vol 2, Iss 1, Pp 169-177 (2021)
Externí odkaz:
https://doaj.org/article/7f4e2ae5adc84abcaeebf8fe0320de15
Autor:
Peter G. Chandler, Ashley M. Buckle
Publikováno v:
Cells, Vol 9, Iss 3, p 610 (2020)
As a non-antibody scaffold, monobodies based on the fibronectin type III (FN3) domain overcome antibody size and complexity while maintaining analogous binding loops. However, antibodies and their derivatives remain the gold standard for the design o
Externí odkaz:
https://doaj.org/article/0f970e4bb68d499fa60356f9c7cd445a
Autor:
Ruoxin Wang, Ashley M. Buckle, Peter G. Chandler, David Rudd, Meri Ayurini, Joel F. Hooper, Paul D. O’Leary, Karen D. Milewska, Lara R. Malins
Publikováno v:
JACS Au
JACS Au, Vol 2, Iss 1, Pp 169-177 (2021)
JACS Au, Vol 2, Iss 1, Pp 169-177 (2021)
Cobalt-mediated radical polymerizations (CMRPs) have been initiated by the radical decarboxylation of tetrachlorophthalimide activated esters. This allows for the controlled radical polymerization of activated monomers across a broad temperature rang
Publikováno v:
Wound Repair and Regeneration. 27:562-590
Compression therapy is the current evidence-based approach to manage venous leg ulcers (VLU); however, adherence is a major barrier to successful treatment. Combination approaches may relieve the burden of treatment by shortening the time to ulcer he
Autor:
Colin J. Jackson, Li Lynn Tan, James S. Green, Sebastian S. Broendum, Robert J. Falconer, Peter G. Chandler, Benjamin T. Porebski, Blake T. Riley, David E. Hoke, Trent P. Munro, Ashley M. Buckle, Malcolm Buckle
Publikováno v:
The Journal of Biological Chemistry
The fibronectin type III (FN3) monobody domain is a promising non-antibody scaffold, which features a less complex architecture than an antibody while maintaining analogous binding loops. We previously developed FN3Con, a hyperstable monobody derivat
Autor:
Colin J. Jackson, Sebastian S. Broendum, Peter G. Chandler, Blake T. Riley, Robert J. Falconer, David E. Hoke, Li Lynn Tan, Trent P. Munro, Benjamin T. Porebski, Malcolm Buckle, Ashley M. Buckle, James S. Green
The fibronectin type III (FN3) monobody domain is a promising non-antibody scaffold which features a less complex architecture than an antibody while maintaining analogous binding loops. We previously developed FN3Con, a hyper-stable monobody derivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbf8f0095b7dcf4297d9dd8dfff253f0
https://doi.org/10.1101/2020.12.14.422768
https://doi.org/10.1101/2020.12.14.422768
Autor:
Lara R. Malins, Meri Ayurini, Peter G. Chandler, David Rudd, Ashley M. Buckle, Joel F. Hooper, Karen D. Milewska
Cobalt-mediated radical polymerisations (CMRPs) have been initiated by the radical decarboxylation of tetrachlorophthalimide activated esters. This allows for the controlled radical polymerisation of both activated and less activated monomers across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd3e36827f84716f1f8495cc9aa88903
https://doi.org/10.26434/chemrxiv.13185572.v1
https://doi.org/10.26434/chemrxiv.13185572.v1
Autor:
Sarah N. Le, Ashley M. Buckle, Peter G. Chandler, David E. Hoke, Monika Gora, Marlena Godlewska, Daniel E. Williams, J. Paul Banga
Publikováno v:
Endocrinology. 161
Thyroid peroxidase (TPO) is a critical membrane-bound enzyme involved in the biosynthesis of multiple thyroid hormones, and is a major autoantigen in autoimmune thyroid diseases such as destructive (Hashimoto) thyroiditis. Here we report the biophysi
Autor:
Sarah N. Le, Daniel E. Williams, Peter G. Chandler, David E. Hoke, J. Paul Banga, Monika Gora, Ashley M. Buckle, Marlena Godlewska
Thyroid peroxidase (TPO) is a critical membrane-bound enzyme involved in the biosynthesis of multiple thyroid hormones, and is a major autoantigen in autoimmune thyroid diseases such as Graves’ disease and Hashimoto’s thyroiditis. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fab03e5518ddcb795aad55f80b54fd
Autor:
Peter G, Chandler, Sebastian S, Broendum, Blake T, Riley, Matthew A, Spence, Colin J, Jackson, Sheena, McGowan, Ashley M, Buckle
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2073
The stability of wild-type proteins is often a hurdle to their practical use in research, industry, and medicine. The route to engineering stability of a protein of interest lies largely with the available data. Where high-resolution structural data