Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Peter G, Stanton"'
Autor:
Daniela Fietz, Raouda Sgaier, Liza O’Donnell, Peter G. Stanton, Laura F. Dagley, Andrew I. Webb, Hans-Christian Schuppe, Thorsten Diemer, Adrian Pilatz
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionAzoospermia, characterized by an absence of sperm in the ejaculate, represents the most severe form of male infertility. While surgical sperm retrieval in obstructive azoospermia (OA) is successful in the majority of cases, patients with
Externí odkaz:
https://doaj.org/article/05dd56e6fba143f3ae70adeae3afa88a
Spermatogonial fate in mice with increased activin A bioactivity and testicular somatic cell tumours
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Adult male fertility depends on spermatogonial stem cells (SSCs) which undergo either self-renewal or differentiation in response to microenvironmental signals. Activin A acts on Sertoli and Leydig cells to regulate key aspects of testis development
Externí odkaz:
https://doaj.org/article/0206b3d1ce1449d0bb1b99aa6426ecc0
Autor:
Liza O’Donnell, Laura F. Dagley, Michael Curley, Annalucia Darbey, Peter J. O’Shaughnessy, Thorsten Diemer, Adrian Pilatz, Daniela Fietz, Peter G. Stanton, Lee B. Smith, Diane Rebourcet
Publikováno v:
PLoS ONE, Vol 18, Iss 9 (2023)
Sertoli cells support the development of sperm and the function of various somatic cells in the interstitium between the tubules. Sertoli cells regulate the function of the testicular vasculature and the development and function of the Leydig cells t
Externí odkaz:
https://doaj.org/article/b12856a5a9754a999cd00b7cc1ae9dd5
Publikováno v:
Asian Journal of Andrology, Vol 18, Iss 4, Pp 620-626 (2016)
The Sertoli cell tight junction (TJ) is the key component of the blood-testis barrier, where it sequesters developing germ cells undergoing spermatogenesis within the seminiferous tubules. Hormonally regulated claudin-11 is a critical transmembrane p
Externí odkaz:
https://doaj.org/article/fe1def8776ad401d935685625402f98c
Publikováno v:
Reproductive Sciences. 28:2916-2928
Cryptorchidism causes spermatogenic failure and reduced serum androgen levels, as well as testicular oedema and fibrosis, which are hallmarks of inflammation. However, the role of inflammation and the effects of cryptorchidism on Sertoli cell and Ley
Autor:
Beatriz Martín-Fernández, Natalia de las Heras, María Valero-Muñoz, Sandra Ballesteros, Yi-Zhou Yao, Peter G Stanton, Peter J Fuller, Vicente Lahera
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111104 (2014)
Aldosterone administration in rats results in several cardiac alterations. Previous studies have demonstrated that proanthocyanidins, phenolic bioactive compounds, have cardioprotective effects. We studied the potential beneficial effects of the proa
Externí odkaz:
https://doaj.org/article/8c1c3839b16142b483aea4d6a5fa7d37
Autor:
Peter G. Stanton, Lee B. Smith, Julien M. D. Legrand, Giuseppe Infusini, Frédéric Chalmel, Diane Rebourcet, Andrew I. Webb, Raouda Sgaier, Laura F. Dagley, Adrian Pilatz, Robin M. Hobbs, Wolfgang Weidner, Liza O'Donnell, Robert I McLachlan, Thorsten Diemer, Daniela Fietz, Peter J. O'Shaughnessy
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (3), pp.e21397. ⟨10.1096/fj.202002484R⟩
FASEB Journal, 2021, 35 (3), pp.e21397. ⟨10.1096/fj.202002484R⟩
The FASEB Journal
FASEB J
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (3), pp.e21397. ⟨10.1096/fj.202002484R⟩
FASEB Journal, 2021, 35 (3), pp.e21397. ⟨10.1096/fj.202002484R⟩
The FASEB Journal
FASEB J
International audience; Sperm develop from puberty in the seminiferous tubules, inside the blood-testis barrier to prevent their recognition as "non-self" by the immune system, and it is widely assumed that human sperm-specific proteins cannot access
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fa447f4187acfb621b5d367509ed92
https://hal.archives-ouvertes.fr/hal-03169602
https://hal.archives-ouvertes.fr/hal-03169602
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 28(10)
Cryptorchidism causes spermatogenic failure and reduced serum androgen levels, as well as testicular oedema and fibrosis, which are hallmarks of inflammation. However, the role of inflammation and the effects of cryptorchidism on Sertoli cell and Ley
Autor:
Peter G Stanton, Pavel Sluka, Caroline F H Foo, Andrew N Stephens, A Ian Smith, Robert I McLachlan, Liza O'Donnell
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41718 (2012)
The production of mature sperm is reliant on androgen action within the testis, and it is well established that androgens act on receptors within the somatic Sertoli cells to stimulate male germ cell development. Mice lacking Sertoli cell androgen re
Externí odkaz:
https://doaj.org/article/8a0c3d1c1b84468bb347ad9bb48f59db
Autor:
Peter G. Stanton, Kate L Loveland, Mark P. Hedger, Nour Nicolas, Justin L. Chen, D. M. De Kretser, Sudhanshu Bhushan, Paul Gregorevic, Susan Hayward, Andreas Meinhardt, Monika Fijak, Julie A Muir
Publikováno v:
Reproduction. 154:293-305
Experimental autoimmune orchitis (EAO) is a rodent model of chronic testicular inflammation that mimics the pathology observed in some types of human infertility. In a previous study, testicular expression of the inflammatory/immunoregulatory cytokin