Zobrazeno 1 - 10
of 399
pro vyhledávání: '"Peter G, Shields"'
Autor:
Devki Patel, Joseph P. McElroy, Daniel Y. Weng, Kamel Sahar, Sarah A. Reisinger, Jo L. Freudenheim, Mark D. Wewers, Peter G. Shields, Min-Ae Song
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Lung cancer exhibits sex-biased molecular characteristics and epidemiological trends, suggesting a need for sex-specific approaches to understanding its etiology and treatment. DNA methylation alterations play critical roles in lung carcinog
Externí odkaz:
https://doaj.org/article/413d5151e0d44b7fb069738a4d0c5a80
Autor:
Min-Ae Song, Kellie M. Mori, Joseph P. McElroy, Jo L. Freudenheim, Daniel Y. Weng, Sarah A. Reisinger, Theodore M. Brasky, Mark D. Wewers, Peter G. Shields
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Cigarette smoking and aging are the main risk factors for pulmonary diseases, including cancer. Epigenetic aging may explain the relationship between smoking, electronic cigarette vaping, and pulmonary health. No study has examine
Externí odkaz:
https://doaj.org/article/21f2f1b269dd4f138393216a2b4f7964
Autor:
Dan H Barouch, Yi Wang, Mark P Rubinstein, Zihai Li, Anqi Li, Sarah Reisinger, Peter G Shields, Qin Ma, No-Joon Song, Dongjun Chung, Karthik B Chakravarthy, Chelsea Bolyard, Hyeongseon Jeon, Kelsi Reynolds, Kevin P Weller, Sizun Jiang, Eugene M Oltz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is highly transmissible and evades pre-established immunity. Messenger RNA (mRNA) vaccination against ancestral strain spike protein can induce intact T-cell
Externí odkaz:
https://doaj.org/article/a52a3aaab70c4bc4b814b6816e637492
Autor:
Peter G. Shields
Publikováno v:
Addiction Neuroscience, Vol 7, Iss , Pp 100098- (2023)
Tobacco research remains a clear priority to improve individual and population health, and has recently become more complex with emerging combustible and noncombustible tobacco products. The use of omics methods in prevention and cessation studies ar
Externí odkaz:
https://doaj.org/article/4e17c698a1d74a4fb2641f53f0b81b39
Autor:
Joseph H. Azar, John P. Evans, Madison H. Sikorski, Karthik B. Chakravarthy, Selah McKenney, Ian Carmody, Cong Zeng, Rachael Teodorescu, No-Joon Song, Jamie L. Hamon, Donna Bucci, Maria Velegraki, Chelsea Bolyard, Kevin P. Weller, Sarah A. Reisinger, Seema A. Bhat, Kami J. Maddocks, Nathan Denlinger, Narendranath Epperla, Richard J. Gumina, Anastasia N. Vlasova, Eugene M. Oltz, Linda J. Saif, Dongjun Chung, Jennifer A. Woyach, Peter G. Shields, Shan-Lu Liu, Zihai Li, Mark P. Rubinstein
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
We assessed vaccine-induced antibody responses to the SARS-CoV-2 ancestral virus and Omicron variant before and after booster immunization in 57 patients with B cell malignancies. Over one-third of vaccinated patients at the pre-booster time point we
Externí odkaz:
https://doaj.org/article/094df6d1a4bf45e8b2832d1cf020148e
Autor:
Barbara L Andersen, John Myers, Tessa Blevins, Kylie R Park, Rachel M Smith, Sarah Reisinger, David P Carbone, Carolyn J Presley, Peter G Shields, William E Carson
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0282206 (2023)
Lung cancer is a product of inflammation and a dysfunctional immune system, and depression has similar dysregulation. Depression disproportionately affects lung cancer patients, having the highest rates of all cancers. Systemic inflammation and depre
Externí odkaz:
https://doaj.org/article/f40278a7ccd64d939105c58ed313b0ee
Autor:
Kellie M. Mori, Joseph P. McElroy, Daniel Y. Weng, Sangwoon Chung, Paolo Fadda, Sarah A. Reisinger, Kevin L. Ying, Theodore M. Brasky, Mark D. Wewers, Jo L. Freudenheim, Peter G. Shields, Min-Ae Song
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104301- (2022)
Summary: Background: Mitochondrial DNA copy number (mtCN) maintains cellular function and homeostasis, and is linked to nuclear DNA methylation and gene expression. Increased mtCN in the blood is associated with smoking and respiratory disease, but h
Externí odkaz:
https://doaj.org/article/4a7cfecacdf249ceb5519c4fc308155a
Autor:
Cong Zeng, John P. Evans, Sarah Reisinger, Jennifer Woyach, Christina Liscynesky, Zeinab El Boghdadly, Mark P. Rubinstein, Karthik Chakravarthy, Linda Saif, Eugene M. Oltz, Richard J. Gumina, Peter G. Shields, Zihai Li, Shan-Lu Liu
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract There is currently a critical need to determine the efficacy of SARS-CoV-2 vaccination for immunocompromised patients. In this study, we determined the neutralizing antibody response in 160 cancer patients diagnosed with chronic lymphocytic
Externí odkaz:
https://doaj.org/article/b0b75e1c41084268a96830ebeb2c2906
Autor:
Amarnath Singh, Garrett Kinnebrew, Ping-Ching Hsu, Daniel Y. Weng, Min-Ae Song, Sarah A. Reisinger, Joseph P. McElroy, Brittney Keller-Hamilton, Amy K. Ferketich, Jo L. Freudenheim, Peter G. Shields
Publikováno v:
Metabolites, Vol 13, Iss 8, p 899 (2023)
Obesity in children and adolescents has increased globally. Increased body mass index (BMI) during adolescence carries significant long-term adverse health outcomes, including chronic diseases such as cardiovascular disease, stroke, diabetes, and can
Externí odkaz:
https://doaj.org/article/d9faa269de9a4847a399c1c58ca4e111
Autor:
Peter G. Shields, Kevin L. Ying, Theodore M. Brasky, Jo L. Freudenheim, Zihai Li, Joseph P. McElroy, Sarah A. Reisinger, Min-Ae Song, Daniel Y. Weng, Mark D. Wewers, Noah B. Whiteman, Yiping Yang, Ewy A. Mathé
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1405 (2023)
Smokers (SM) have increased lung immune cell counts and inflammatory gene expression compared to electronic cigarette (EC) users and never-smokers (NS). The objective of this study is to further assess associations for SM and EC lung microbiomes with
Externí odkaz:
https://doaj.org/article/86e29905cafc41bba651243ac132bcd6