Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Peter G, Hains"'
Autor:
Rebecca C. Poulos, Peter G. Hains, Rohan Shah, Natasha Lucas, Dylan Xavier, Srikanth S. Manda, Asim Anees, Jennifer M. S. Koh, Sadia Mahboob, Max Wittman, Steven G. Williams, Erin K. Sykes, Michael Hecker, Michael Dausmann, Merridee A. Wouters, Keith Ashman, Jean Yang, Peter J. Wild, Anna deFazio, Rosemary L. Balleine, Brett Tully, Ruedi Aebersold, Terence P. Speed, Yansheng Liu, Roger R. Reddel, Phillip J. Robinson, Qing Zhong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Clinical proteomics critically depends on the ability to acquire highly reproducible data over an extended period of time. Here, the authors assess reproducibility over four months across different mass spectrometers and develop a computational appro
Externí odkaz:
https://doaj.org/article/f31d48fe5cbd4e4fb32261099a109959
Autor:
Fiona M. Deane, Andrew J. S. Lin, Peter G. Hains, Sarah L. Pilgrim, Phillip J. Robinson, Adam McCluskey
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3828-3838 (2017)
Externí odkaz:
https://doaj.org/article/13b7928be0ea4fb1904544dc5a3aab77
Autor:
Qing Zhong, Sun Rui, Adel T. Aref, Zainab Noor, Asim Anees, Yi Zhu, Natasha Lucas, Rebecca C. Poulos, Mengge Lyu, Tiansheng Zhu, Bo Wang, Guo-Bo Chen, Yingrui Wang, Xuan Ding, Dorothea Rutishauser, Niels J. Rupp, Jan H. Rueschoff, Cédric Poyet, Thomas Hermanns, Christian Fankhauser, María Rodríguez Martínez, Wenguang Shao, Marija Buljan, Janis Frederick Neumann, Andreas Beyer, Peter G. Hains, Roger R. Reddel, Phillip J. Robinson, Ruedi Aebersold, Tiannan Guo, Peter J. Wild
Gleason grading is an important prognostic indicator for prostate adenocarcinoma and is crucial for patient treatment decisions. However, intermediate-risk patients diagnosed in Gleason Grade Groups (GG) 2 and GG3 can harbour either aggressive or non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2f4ccbf04dadb90601b2263971c4a9e
https://doi.org/10.1101/2023.03.03.530910
https://doi.org/10.1101/2023.03.03.530910
Autor:
Emanuel Gonçalves, Rebecca C Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J Seneviratne, Erin Sykes, Frances Thomas, Sara Valentini, Steven G Williams, Yangxiu Wu, Dylan Xavier, Karen L MacKenzie, Peter G Hains, Brett Tully, Phillip J Robinson, Qing Zhong, Mathew J Garnett, Roger R Reddel
SummaryThe proteome provides unique insights into biology and disease beyond the genome and transcriptome. Lack of large proteomic datasets has restricted identification of new cancer biomarkers. Here, proteomes of 949 cancer cell lines across 28 tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ab6090375c95783a1345c281a33a98b
https://doi.org/10.1101/2022.02.26.482008
https://doi.org/10.1101/2022.02.26.482008
Autor:
Emanuel Gonçalves, Rebecca C. Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yangxiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip J. Robinson, Qing Zhong, Mathew J. Garnett, Roger R. Reddel
Publikováno v:
Cancer Cell
The proteome provides unique insights into disease biology beyond the genome and transcriptome. A lack of large proteomic datasets has restricted the identification of new cancer biomarkers. Here, proteomes of 949 cancer cell lines across 28 tissue t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3a20c7e98090d73382989efa0e217c
https://pubmed.ncbi.nlm.nih.gov/35839778
https://pubmed.ncbi.nlm.nih.gov/35839778
Autor:
Mark P. Hodson, Phillip J. Robinson, Roland Stocker, Peter G. Hains, Jihan Talib, Sergey Tumanov
Publikováno v:
Analytical Chemistry. 91:12670-12679
Atherosclerosis is a complex, multifactorial disease characterized by the buildup of plaque in the arterial wall. Apolipoprotein E gene deficient (Apoe-/-) mice serve as a commonly used tool to elucidate the pathophysiology of atherosclerosis because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325222a0828f09e1ad9ef1ffff0ff954
https://doi.org/10.1021/acs.analchem.9b01842
https://doi.org/10.1021/acs.analchem.9b01842
Autor:
Stephen A. Wood, Peter G. Hains, Arnaud Muller, Melissa Hill, Susitha Premarathne, Mariyam Murtaza, Phillip J. Robinson, George D. Mellick, Alex M. Sykes
Publikováno v:
PROTEOMICS – Clinical Applications. 16:2200015
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease. It is generally diagnosed clinically after the irreversible loss of dopaminergic neurons and no general biomarkers currently exist. To gain insight into the underlying c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f389525bc14c685e5f6f0ada1ca670
https://doi.org/10.1002/prca.202200015
https://doi.org/10.1002/prca.202200015
Autor:
Keith Ashman, Asim Anees, Terence P. Speed, Erin K. Sykes, Roger R. Reddel, Yansheng Liu, Jennifer M. S. Koh, Jean Yang, Merridee A. Wouters, Steven G. Williams, Peter J. Wild, Anna deFazio, Natasha Lucas, Max Wittman, Dylan Xavier, Michael Hecker, Sadia Mahboob, Michael Dausmann, Ruedi Aebersold, Peter G. Hains, Brett Tully, Rohan Shah, Phillip J. Robinson, Qing Zhong, Rosemary L. Balleine, Srikanth S. Manda, Rebecca C. Poulos
Publikováno v:
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop computational methods for improving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72057dd71a63badf92c2a0858853f64
https://hdl.handle.net/20.500.11850/430457
https://hdl.handle.net/20.500.11850/430457
Autor:
David Clarke, Sean Peters, Akila J. Seneviratne, Michael Hecker, Brett Tully, Michael Dausmann, Qing Zhong, Peter G. Hains
Publikováno v:
Bioinformatics
Motivation The output of electrospray ionization–liquid chromatography mass spectrometry (ESI-LC-MS) is influenced by multiple sources of noise and major contributors can be broadly categorized as baseline, random and chemical noise. Noise has a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd833b7ad97be42877a5b0d3e5b56cb1
https://pubmed.ncbi.nlm.nih.gov/34323970
https://pubmed.ncbi.nlm.nih.gov/34323970
Autor:
Michael V. Swain, Peter G. Hains, Neil Hunter, Catherine Rathsam, Nattida Charadram, Hans Zoellner, Ramin Mostofi Zadeh Farahani, Valentina A. Valova
Publikováno v:
Journal of Structural Biology. 204:26-37
Proteins of the inter-rod sheath and peptides within the narrow inter-crystallite space of the rod structure are considered largely responsible for visco-elastic and visco-plastic properties of enamel. The present study was designed to investigate pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1c78bace75d273e9cb33df7c640dd8
https://doi.org/10.1016/j.jsb.2018.06.006
https://doi.org/10.1016/j.jsb.2018.06.006