Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Peter Forgiarini"'
Publikováno v:
British Journal of Haematology. 110:985-992
In order to test new orally active iron chelators in a predictive way, a primate model has been developed. This model makes use of the marmoset monkey (Callithrix jacchus) and its overall design is similar to a previously reported monkey model. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cefd82a6ae21a5274b91486e6909674
https://doi.org/10.1046/j.1365-2141.2000.02260.x
https://doi.org/10.1046/j.1365-2141.2000.02260.x
Autor:
Pascal Rigollier, Jeanette Marjorie Wood, Stefan Stutz, Jürgen Maibaum, N. C. Cohen, Joseph Rahuel, Walter Fuhrer, Hans-Peter Baum, Vittorio Rasetti, Walter Schilling, Frederic Cumin, Markus Gruetter, Christian Schnell, Peter Forgiarini, Richard Dr. Göschke, Trixie Wagner
Publikováno v:
Journal of medicinal chemistry. 50(20)
The action of renin is the rate-limiting step of the renin-angiotensin system (RAS), a key regulator of blood pressure. Effective renin inhibitors directly block the RAS entirely at source and, thus, may provide a vital weapon for hypertension therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0798531097bb1d65978851f1e51d48ff
https://pubmed.ncbi.nlm.nih.gov/17824679
https://pubmed.ncbi.nlm.nih.gov/17824679
Publikováno v:
Gastroenterology. 124:A571
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998cc852d965dbfcb56a81492028f345
https://doi.org/10.1016/s0016-5085(03)82890-1
https://doi.org/10.1016/s0016-5085(03)82890-1
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 8(7)
The in vivo effects of two anti-human renin monoclonal antibodies with a high binding affinity for primate renin were studied in conscious, volume-depleted marmosets. These antibodies, R-3-17-7 and R-3-36-16, both have high binding activity for renin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8eb2b84ab8c24599700776f65b9ce9
https://pubmed.ncbi.nlm.nih.gov/3013776
https://pubmed.ncbi.nlm.nih.gov/3013776
Autor:
Dietmar Neisius, Jeanette Marjorie Wood, K. G. Hofbauer, Hans-Peter Baum, Ross A. Jobber, N Gulati, Peter Forgiarini
Publikováno v:
Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 7(2)
We have developed marmoset models for the in vivo evaluation of primate-specific inhibitors of human renin. After acute intravenous administration to normotensive sodium-depleted marmosets, renin inhibitors of different structural types induced a max
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce7a55c0c6d536795deb32bef5fcb0b
https://pubmed.ncbi.nlm.nih.gov/2547039
https://pubmed.ncbi.nlm.nih.gov/2547039
Publikováno v:
General pharmacology. 14(1)
1. The renal vascular responses to the peptide hormones angiotensin II (ANG II), arginine-vasopressin (AVP) and bradykinin (BK) were studied in anaesthetized rats with flow-meter techniques. The contribution of prostaglandins (PG) to their renal vasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05a25778e7a0b565d286f04d93da985
https://pubmed.ncbi.nlm.nih.gov/6826026
https://pubmed.ncbi.nlm.nih.gov/6826026