Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Peter F. McLean"'
Autor:
Yolanda T. Chong, Vlad Rodic, Fiona L. Weathersby, Carl A. Brooks, Michael F. Cuccarese, Nathan H. Lazar, Ian K. Quigley, Christopher C. Gibson, Ronald W. Alfa, Berton A. Earnshaw, Kirk R. Thomas, Michael A. Statnick, Brandon L. Probst, Ben Fogelson, Nicholas D. Campbell, Jes Ford, Kathleen-Rose Skelly, Mason L. Victors, Seth W. Glazier, Peter F. McLean, James D. Jensen, Imran S. Haque, Anne E. Carpenter, Sharath S. Hegde, Chadwick T. Davis, Katie Heiser, Pamela Jacobson, Brandon M. Mendivil, Adeline S. Low, Joseph Carpenter, Elissa D. Pastuzyn, Hannah B. Gordon
Development of accurate disease models and discovery of immune-modulating drugs is challenged by the immune system’s highly interconnected and context-dependent nature. Here we apply deep-learning-driven analysis of cellular morphology to develop a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9c21782616d4199bcf88ffc3650d4b4
https://doi.org/10.1101/2020.08.02.233064
https://doi.org/10.1101/2020.08.02.233064
Autor:
Christopher C. Gibson, Yolanda T. Chong, Peter F. McLean, Mason L. Victors, Adeline S. Low, Ben J. Miller, Hannah B. Gordon, Chadwick T. Davis, Katie Heiser, Imran S. Haque, Pamela Jacobson, Ronald W. Alfa, Berton A. Earnshaw, Ben Fogelson, Brett L. Hurst
To identify potential therapeutic stop-gaps for SARS-CoV-2, we evaluated a library of 1,670 approved and reference compounds in an unbiased, cellular image-based screen for their ability to suppress the broad impacts of the SARS-CoV-2 virus on phenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261a386f110bc743b3822ae37d93cfb4
https://doi.org/10.1101/2020.04.21.054387
https://doi.org/10.1101/2020.04.21.054387
Autor:
Peter F. McLean, Lynn Cooley
Publikováno v:
Fly. 8:13-18
Ring canals are made from arrested cleavage furrows, and provide direct cytoplasmic connections among sibling cells. They are well documented for their participation in Drosophila oogenesis, but little is known about their role in several somatic tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a258d309f055acdcfd00740d62da719f
https://doi.org/10.4161/fly.27016
https://doi.org/10.4161/fly.27016
In mammalian cells, transient gene expression (TGE) is a rapid, minimal-investment alternative to single-copy integrations for testing of transgenic constructs. However, transient gene expression, as measured by flow cytometry with a fluorescent repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2ea23e7275e070746894a8977af7b3
https://doi.org/10.1101/057950
https://doi.org/10.1101/057950
Publikováno v:
Journal of Cell Science. 124:4077-4086
Ring canals connecting Drosophila germline, follicle and imaginal disc cells provide direct contact of cytoplasm between cells. To date, little is known about the formation, structure, or function of the somatic ring canals present in follicle and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e889e4be80ea3b262a0250fc99bf62
https://doi.org/10.1242/jcs.090456
https://doi.org/10.1242/jcs.090456
Publikováno v:
Development. 139:e207-e207
Ring canals connecting Drosophila germline, follicle and imaginal disc cells provide direct contact of cytoplasm between cells. To date, little is known about the formation, structure, or function of the somatic ring canals present in follicle and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0788ce81e3cecc5533849628614f9016
https://doi.org/10.1242/dev.077784
https://doi.org/10.1242/dev.077784