Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Peter F. Flynn"'
Autor:
Cynthia J. Burrows, Peter F. Flynn, Jay P. Kitt, Joel M. Harris, Anton Alenko, Anita M. Orendt, Aaron M. Fleming
Publikováno v:
J Am Chem Soc
The recent report of RBS-Seq to map simultaneously the epitranscriptomic modifications N1-methyladenosine, 5-methylcytosine, and pseudouridine (Ψ) via bisulfite treatment of RNA provides a key advance to locate these important modifications. The loc
Autor:
Robert P. Young, Joshua D. Hartman, Gregory J. O. Beran, Sarah E. Soss, Robbie J. Iuliucci, James K. Harper, Peter F. Flynn, Leonard J. Mueller
Publikováno v:
ChemPhysChem. 18:2225-2232
NMR studies measuring the chemical shift tensors are increasingly being employed to assign structure in difficult-to-crystallize solids. For small organic molecules, such studies usually focus on 13C sites, but proteins and peptides are more commonly
Autor:
Sarah E, Soss, Peter F, Flynn, Robbie J, Iuliucci, Robert P, Young, Leonard J, Mueller, Joshua, Hartman, Gregory J O, Beran, James K, Harper
Publikováno v:
Chemphyschem : a European journal of chemical physics and physical chemistry. 18(16)
NMR studies measuring chemical shift tensors are increasingly being employed to assign structure in difficult-to-crystallize solids. For small organic molecules, such studies usually focus on
Publikováno v:
Journal of the American Chemical Society. 131:8030-8039
Reverse micelles are discrete nanoscale particles composed of a water core surrounded by surfactant. The amount of water within the core of reverse micelles can be easily manipulated to directly affect the size of the reverse micelle particle. The wa
Publikováno v:
The Journal of Peptide Research. 63:17-22
To assess the relative importance of backbone hydrogen bonding (H-bonding) vs. side chain hydrophobicity in protein structural formation, a method called side chain-backbone swap is proposed. Such a method swaps the side chain and backbone portions o
Publikováno v:
Journal of Biomolecular NMR. 40:203-211
Membrane protein structural biology is a rapidly developing field with fundamental importance for elucidating key biological and biophysical processes including signal transduction, intercellular communication, and cellular transport. In addition to
Autor:
Peter F. Flynn, Sarah E. Soss
Publikováno v:
Biochemistry. 46:14979-14986
The kink-turn (K-turn) motif is recognized and bound by a family of proteins that act as nucleation factors for ribonucleoparticle assembly. The binding of various proteins to a conserved RNA structural motif known as the K-turn has been shown to be
Publikováno v:
Journal of the American Chemical Society. 128:5082-5090
The effects of low temperature and ionic strength on water encapsulated within reverse micelles were investigated by solution NMR. Reverse micelles composed of AOT and pentane and solutions with varying concentrations of NaCl were studied at temperat
Publikováno v:
Chemistry of Materials. 17:6583-6588
Peptide-based hydrogels have gained interest for biomedical applications as a result of their biodegradability and bioresorbability. For in vivo applications, these hydrogels should be able to easi...
Publikováno v:
Journal of the American Chemical Society. 127:13553-13560
Water-soluble proteins encapsulated within reverse micelles may be studied under a variety of conditions, including low temperature and a wide range of buffer conditions. Direct high-resolution detection of information relating to protein folding int