Výsledky vyhledávání - "Peter F. Curle"

Anxiolytic properties of (+) s 20499, a novel serotonin 5-HT1A full agonist, in the elevated plus-maze and social interaction tests

Autor: Elisabeth Mocaër, Pierre Renard, Peter F. Curle, Beatrice Guardiola

Publikováno v: Drug Development Research. 32:183-190

Previous studies have shown that (±) S 20244 (8-(4-[N-(5-methoxychroman-3-yl)N-propylamino] butyl) 8-azaspiro[4,5]decane-7,9 dione) and its isomers (+) S 20499 and (−) S 20500 are full agonists at 5-HT1A receptors. In the present study, the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b29c21d1f16256e2edfb305d24e29f8d
https://doi.org/10.1002/ddr.430320308

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Anxiety in the rat is associated with decreased release of 5-HT and glycine from the hippocampus

Autor: Sandra E. File, Helen A. Baldwin, Michael J. Neal, Peter F. Curle

Publikováno v: Neuroscience letters. 83(3)

Rats, implanted with dialysis loops in the dorsal hippocampus, were injected with subconvulsant doses of pentylenetetrazole (PTZ 15 and 30 mg/kg) and a 30-min sample collected for high-performance liquid chromatography (HPLC) analysis of amines and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8e013fede9d462b774af40e1adfc07
https://pubmed.ncbi.nlm.nih.gov/3441314

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