Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Peter F Kador"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Blast wave exposure, a leading cause of hearing loss and balance dysfunction among military personnel, arises primarily from direct mechanical damage to the mechanosensory hair cells and supporting structures or indirectly through excessive
Externí odkaz:
https://doaj.org/article/f0a96ac11a5b446b9e2ad72ee9d33d32
Autor:
Peter F Kador, Peng Zhang, Jun Makita, Zifeng Zhang, Changmei Guo, James Randazzo, Hiroyoshi Kawada, Neena Haider, Karen Blessing
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e49422 (2012)
Mouse models possessing green fluorescent protein (GFP) and/or human aldose reductase (hAR) in vascular tissues have been established and crossed with naturally diabetic Akita mice to produce new diabetic mouse models.Colonies of transgenic C57BL mic
Externí odkaz:
https://doaj.org/article/f78f137389ec4472a66891a5e4d1d28d
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18980 (2011)
Age-related cataract is a worldwide health care problem whose progression has been linked to oxidative stress and the accumulation of redox-active metals. Since there is no specific animal model for human age-related cataract, multiple animal models
Externí odkaz:
https://doaj.org/article/9de3e4b1bea74a54badd267474f0c238
Autor:
Zi-Feng Zhang, Jian Zhang, Yan-Nian Hui, Min-Hua Zheng, Xin-Ping Liu, Peter F Kador, Yu-Sheng Wang, Li-Bo Yao, Jian Zhou
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26102 (2011)
BACKGROUND: Human N-Myc downstream regulated gene2 (NDRG2), a novel gene has been cloned and shown to be related to a number of cellular processes, including proliferation, differentiation, stress, and apoptosis. NDRG2 has also been linked to age-rel
Externí odkaz:
https://doaj.org/article/47e03e802aa94efba2a0a40492702adc
Autor:
Peter F. Kador, Richard Salvi
Publikováno v:
Antioxid Redox Signal
SIGNIFICANCE: Oxidative stress contributes to vision, hearing and neurodegenerative disorders. Currently, no treatments prevent these disorders; therefore, there is an urgent need for redox modulators that can prevent these disorders. RECENT ADVANCES
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f31b183ffbc0cc26728dee28396980
https://europepmc.org/articles/PMC9221172/
https://europepmc.org/articles/PMC9221172/
Autor:
K. Krishna Sharma, Peter F. Kador, Ashutosh S. Phadte, Marjorie F. Lou, Puttur Santhoshkumar, Damian M. Daszynski, Haizhen A. Zhong
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
The paradigm that cataracts are irreversible and that vision from cataracts can only be restored through surgery has recently been challenged by reports that oxysterols such as lanosterol and 25-hydroxycholesterol can restore vision by binding to αB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f48cba3f41f04ae1fafb52d4b945629
http://link.springer.com/article/10.1038/s41598-019-44676-4
http://link.springer.com/article/10.1038/s41598-019-44676-4
Autor:
Dalian Ding, Guang-Di Chen, Richard Salvi, Damian M. Daszynski, Haiyan Jiang, Theodor A Woolman, Karen Blessing, Peter F. Kador
Publikováno v:
Hear Res
Oxidative stress is a major contributor to noise-induced hearing loss, the most common cause of hearing loss among military personnel and young adults. HK-2 is a potent, orally-active, multifunctional, redox-modulating drug that has been shown to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b853d0d5898f6e296ecba0d4c125429
https://pubmed.ncbi.nlm.nih.gov/31945692
https://pubmed.ncbi.nlm.nih.gov/31945692
Autor:
Peter F. Kador, Frank J. Giblin
Publikováno v:
Experimental Eye Research. 180:75-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d8e6d02d4e91243e30a4a87e27b6efe
https://doi.org/10.1016/j.exer.2018.12.002
https://doi.org/10.1016/j.exer.2018.12.002
Autor:
Karen Blessing, Hiroyoshi Kawada, Tomomi Kiyota, Peter F. Kador, Lee C. Winchester, Theodor A Woolman
Publikováno v:
Journal of Alzheimer's Disease. 44:297-307
Background Redox-active metal dyshomeostasis and oxidative stress are associated with mitochondrial dysfunction and amyloid-β (Aβ) neurotoxicity that are linked to both the development of age-related macular degeneration (AMD) and Alzheimer's disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e5b3c234f3381eaac93ed44daf751e
https://doi.org/10.3233/jad-132471
https://doi.org/10.3233/jad-132471
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 30:593-602
Based on the hypothesis that oral nutraceuticals do not adequately reach all ocular tissues in the anterior segment, we evaluated the ability of a 3% concentration of the ingredients in a topical nutraceutical antioxidant formulation called Optixcare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70180c474abf42c173bd03f6a610e3ab
https://doi.org/10.1089/jop.2014.0016
https://doi.org/10.1089/jop.2014.0016