Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Peter F Favreau"'
Human induced pluripotent stem cell-derived planar neural organoids assembled on synthetic hydrogels
Autor:
Joydeb Majumder, Elizabeth E Torr, Elizabeth A Aisenbrey, Connie S Lebakken, Peter F Favreau, William D Richards, Yanhong Yin, Qiang Chang, William L Murphy
Publikováno v:
Journal of Tissue Engineering, Vol 15 (2024)
The tailorable properties of synthetic polyethylene glycol (PEG) hydrogels make them an attractive substrate for human organoid assembly. Here, we formed human neural organoids from iPSC-derived progenitor cells in two distinct formats: (i) cells see
Externí odkaz:
https://doaj.org/article/86c87a2ea4184847a73652280ca741fb
Supplementary Figure S1 from MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers
Autor:
Dustin A. Deming, Melissa C. Skala, Michael A. Newton, Kristina A. Matkowskyj, Paraic A. Kenny, Benjamin M. Parsons, Kayla K. Lemmon, Mark E. Burkard, Linda Clipson, Rebecca A. DeStefanis, Gioia Chengcheng Sha, Demetra P. Korkos, Mitchell G. Depke, Dana R. Van De Hey, Alexander E. Yueh, Tyler M. Foley, Cheri A. Pasch, Jeremy D. Kratz, Peter F. Favreau, Susan N. Payne, Stephanie L. Fricke
Supplementary Figure S1 presents the viability of SW48 and SW48PK cells after treatment with BEZ235 and TAK-228 at the 100-400nM concentrations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3797d51c82d44138bbd5766b7be6a207
https://doi.org/10.1158/1535-7163.22507717.v1
https://doi.org/10.1158/1535-7163.22507717.v1
Autor:
Dustin A. Deming, Melissa C. Skala, Michael A. Newton, Kristina A. Matkowskyj, Paraic A. Kenny, Benjamin M. Parsons, Kayla K. Lemmon, Mark E. Burkard, Linda Clipson, Rebecca A. DeStefanis, Gioia Chengcheng Sha, Demetra P. Korkos, Mitchell G. Depke, Dana R. Van De Hey, Alexander E. Yueh, Tyler M. Foley, Cheri A. Pasch, Jeremy D. Kratz, Peter F. Favreau, Susan N. Payne, Stephanie L. Fricke
PIK3CA mutations are common in clinical molecular profiling, yet an effective means to target these cancers has yet to be developed. MTORC1 inhibitors are often used off-label for patients with PIK3CA mutant cancers with only limited data to support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61eef4938e53e1487200610ced459f4f
https://doi.org/10.1158/1535-7163.c.6538765.v1
https://doi.org/10.1158/1535-7163.c.6538765.v1
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Dot plots corresponding to population distribution curves and graphs of individual replicates for bar graphs in Figure 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7330c7bce5376c4f183eb6067b2815ec
https://doi.org/10.1158/1078-0432.22469583
https://doi.org/10.1158/1078-0432.22469583
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Purpose:Cancer treatment is limited by inaccurate predictors of patient-specific therapeutic response. Therefore, some patients are exposed to unnecessary side effects and delays in starting effective therapy. A clinical tool that predicts treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc31f39d9132103e6f6e0d614838406
https://doi.org/10.1158/1078-0432.c.6527292.v1
https://doi.org/10.1158/1078-0432.c.6527292.v1
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a9f8e60a6ce76e9a5440e0c2b3b870
https://doi.org/10.1158/1078-0432.22469568.v1
https://doi.org/10.1158/1078-0432.22469568.v1
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Success rates for growing human cancers in spheroid culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebdc403191475e5e340316a507abb58
https://doi.org/10.1158/1078-0432.22469565
https://doi.org/10.1158/1078-0432.22469565
Autor:
Sheena C. Kerr, Brian P. Johnson, Megan K. Livingston, Molly M. Morgan, Karina M. Lugo-Cintrón, Amani A. Gillette, Melissa C. Skala, Joshua M. Lang, Logan Florek, David J. Beebe, Peter F. Favreau
Publikováno v:
Integrative Biology
The prostate tumor microenvironment (TME) is strongly immunosuppressive; it is largely driven by alteration in cell phenotypes (i.e. tumor-associated macrophages and exhausted cytotoxic T cells) that result in pro-tumorigenic conditions and tumor gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297b85c4b73e3636a1974308a5577abf
https://doi.org/10.1093/intbio/zyaa020
https://doi.org/10.1093/intbio/zyaa020
Autor:
Samantha J. Anderson, Nataliya Volodymyrivna Uboha, Kayla K. Lemmon, Charles P. Heise, Michael F. Bassetti, Katherine A. Johnson, Jeremy D. Kratz, Devon Miller, Sam J. Lubner, Jens C. Eickhoff, Melissa C. Skala, Austin H. Yeung, Evie Carchman, Kristina A. Matkowskyj, Randall J. Kimple, Cristina B. Sanger, Eugene F. Foley, Aishwarya Sunil, Alyssa K. DeZeeuw, Amani A. Gillette, Shujah Rehman, Carley M. Sprackling, Daniel Mulkerin, Linda Clipson, Sean J. McIlwain, Daniel E. Abbott, Lucas C. Zarling, Cheri A. Pasch, Dustin A. Deming, Peter F. Favreau, Elise H. Lawson, Mark E. Burkard, Irene M. Ong, Noelle K. LoConte
Tumor heterogeneity is predicted to confer inferior clinical outcomes, however modeling heterogeneity in a manner that still represents the tumor of origin remains a formidable challenge. Sequencing technologies are limited in their ability to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60f052746f9774871c9acc42f5093d6d
https://doi.org/10.1101/2021.10.15.464556
https://doi.org/10.1101/2021.10.15.464556
Autor:
Peter F. Favreau, Thomas C. Rich, Brenner Sweat, Naga S. Annamdevula, Silas J. Leavesley, Caitlyn Abbott
Publikováno v:
Proc SPIE Int Soc Opt Eng
Over the past 2 decades, hyperspectral imaging technologies have been adapted to address the need for molecule-specific identification in the biomedical imaging field. Applications have ranged from single-cell microscopy to whole-animal in vivo imagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068f26a95ce155d6e9d0efff4cad0ca8
https://pubmed.ncbi.nlm.nih.gov/34054187
https://pubmed.ncbi.nlm.nih.gov/34054187