Výsledky vyhledávání - "Peter Elepfandt"

Oligodeoxynucleotides induce brain inflammation in rats when infused intracerebroventricularly

Autor: Peter Elepfandt, Stefan Rupprecht, Britta Schöning-Burkhardt, Hans-Dieter Volk, Christian Woiciechowsky

Publikováno v: Neuroscience Letters. 322:107-110

Antisense oligodeoxynucleotides (ODNs) can inhibit gene expression in a specific manner. However, several studies described problems with cerebral ODN application. Here, we investigated the immune effects (interleukin-6 (IL-6) release, cell invasion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f245d47713738514a71511626e3070
https://doi.org/10.1016/s0304-3940(02)00093-9

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Continuous infusion of proinflammatory cytokines into the brain to study brain cytokine induced local and systemic immune effects

Autor: Britta Schöning, Christian Woiciechowsky, Wolfgang R. Lanksch, Peter Elepfandt, Hans-Dieter Volk

Publikováno v: Brain research. Brain research protocols. 4(2)

Proinflammatory cytokines are produced in the brain after various kinds of insult (ischemia, trauma, infection). In this process interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α are most important. These cytokines are key mediators of in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67277ebb742ed992b226d7109c84853
https://pubmed.ncbi.nlm.nih.gov/10446417

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