Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Peter E. Shaw"'
Autor:
Charles Ducker, Peter E. Shaw
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5119 (2021)
Genome expansion, whole genome and gene duplication events during metazoan evolution produced an extensive family of ETS genes whose members express transcription factors with a conserved winged helix-turn-helix DNA-binding domain. Unravelling their
Externí odkaz:
https://doaj.org/article/7184d3a27fc64c6fb620d2d04c43a820
Autor:
Claire Soave, Charles Ducker, Naeyma Islam, Seongho Kim, Sally Yurgelevic, Nathan I. Nicely, Luke Pardy, Yanfang Huang, Peter E. Shaw, Gregory Auner, Alex Dickson, Manohar Ratnam
Publikováno v:
Molecular Pharmacology. 103:211-220
Supplementary Methods, Figures 1-9 from Modulation of Gene Expression and Tumor Cell Growth by Redox Modification of STAT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896b3d791f824ae65a24d27c8a4aa327
https://doi.org/10.1158/0008-5472.22384877.v1
https://doi.org/10.1158/0008-5472.22384877.v1
Publikováno v:
Protein expression and purification. 203
Post-translational modifications (PTMs) are important for protein folding and activity, and the ability to recreate physiologically relevant PTM profiles on recombinantly-expressed proteins is vital for meaningful functional analysis. The ETS transcr
Autor:
Leo Kam Yuen Chow, Alexander McGregor, Thomas Strahl, Janice Saxton, Charles Ducker, Peter E. Shaw, Jürgen Handwerger, Robert Layfield
Publikováno v:
Nucleic Acids Research
ELK-1 is a transcription factor involved in ERK-induced cellular proliferation. Here, we show that its transcriptional activity is modulated by ubiquitination at lysine 35 (K35). The level of ubiquitinated ELK-1 rises in mitogen-deprived cells and fa
Autor:
Franziska Gehringer, Peter E. Shaw, Charles Ducker, Janice Saxton, Reyna Sara Quintero-Barceinas
Publikováno v:
The Journal of Biological Chemistry
The mitogen-responsive, ETS-domain transcription factor ELK-1 stimulates the expression of immediate early genes at the onset of the cell cycle and participates in early developmental programming. ELK-1 is subject to multiple levels of posttranslatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a50c4ba158f8970d57e3747454dc16
https://nottingham-repository.worktribe.com/file/5291909/1/1-s2.0-S0021925820002100-main
https://nottingham-repository.worktribe.com/file/5291909/1/1-s2.0-S0021925820002100-main
Autor:
Nadine Holmes, Peter E. Shaw, Fei Sang, Michela Grillo, Rahul Bhosale, Andrew C. Larner, Carolyn Palmer
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244255 (2020)
PLoS ONE
PLoS ONE
Reactive oxygen species are bona fide intracellular second messengers that influence cell metabolism and aging by mechanisms that are incompletely resolved. Mitochondria generate superoxide that is dis-mutated to hydrogen peroxide, which in turn oxid
Autor:
Peter E. Shaw, Charles Ducker
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5119, p 5119 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 5119, p 5119 (2021)
Genome expansion, whole genome and gene duplication events during metazoan evolution produced an extensive family of ETS genes whose members express transcription factors with a conserved winged helix-turn-helix DNA-binding domain. Unravelling their
Autor:
Peter E. Shaw, Charles Ducker
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 130:105886
Eukaryotic cells perform a range of complex processes, some essential for life, others specific to cell type, all of which are governed by post-translational modifications of proteins. Among the repertoire of dynamic protein modifications, ubiquitina
Autor:
Yanfang Huang, Benjamin L. Kidder, Rayna Rosati, Lisa Polin, Xun Bao, Manohar Ratnam, Dakshnamurthy Selvakumar, Hiroki Kakuta, Andrew M. Fribley, Janice Saxton, Martha J. Larsen, Thomas McFall, Peter E. Shaw, Besa Xhabija, Charles Ducker, Seongho Kim, Jing Li
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 24(24)
Purpose: Testosterone suppression in prostate cancer is limited by serious side effects and resistance via restoration of androgen receptor (AR) functionality. ELK1 is required for AR-dependent growth in various hormone-dependent and castration-resis