Výsledky vyhledávání - "Peter E. Manley"

Undernutrition and Pubertal Timing in Female Survivors of Medulloblastoma and Other Embryonal Tumors

Autor: Laurie E. Cohen, Ari J. Wassner, Peter E. Manley, Jia Zhu, Henry A. Feldman, Christine Chordas

Publikováno v: J Clin Endocrinol Metab

Context Children with brain tumors may have pubertal onset at an inappropriately young chronologic age. Hypothalamic-pituitary irradiation ≥18Gy has been found to be a risk factor; age at irradiation is associated with pubertal timing. However, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4bbf1319b8ded3989fd3a517287454
https://doi.org/10.1210/clinem/dgaa475

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A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1–associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study

Publikováno v: Neuro-oncology, vol 22, iss 10
Neuro Oncol

Background Activation of the mammalian target of rapamycin (mTOR) pathway is observed in neurofibromatosis type 1 (NF1) associated low-grade gliomas (LGGs), but agents that inhibit this pathway, including mTOR inhibitors, have not been studied in thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123ac40b01ec5ff9018c9ba5807f1b91
https://doi.org/10.1093/neuonc/noaa071

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Prevalence and Correlates of Pain in Adolescent and Young Adult Survivors of Pediatric Brain Tumors

Autor: Peter E. Manley, Christine Chordas, Christopher J. Recklitis, Dana Footer, Cori Liptak, Elizabeth Fine

Publikováno v: Journal of Adolescent and Young Adult Oncology. 8:641-648

Purpose: Survivors of pediatric brain tumors (PBTs) are at high risk for medical late effects, including pain. Although pain is common at PBT diagnosis and during treatment, less is known about sur...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96000913ed22edfa9ef9b90ff0b1ddce
https://doi.org/10.1089/jayao.2019.0029

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Increasing value of autopsies in patients with brain tumors in the molecular era

Autor: Robert T. Jones, Pratiti Bandopadhayay, Hart G.W. Lidov, Peter E. Manley, Jared T. Ahrendsen, Kee Kiat Yeo, Sanda Alexandrescu, Mark W. Kieran, Susan N. Chi, Jessica Clymer, Mariella G. Filbin, Keith L. Ligon, Karen Wright

Publikováno v: Journal of Neuro-Oncology. 145:349-355

Pediatric brain tumors are associated with high morbidity and mortality, in part due to insufficient understanding of tumor biology. With limited tissue allocation for research from surgical specimens, a key barrier to improving biological understand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b250e49e1b74cae578379ef1617f50
https://doi.org/10.1007/s11060-019-03302-z

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Sixty years single institutional experience with pediatric craniopharyngioma: between the past and the future

Autor: Peter E. Manley, Nicole J. Ullrich, R Michael Scott, Liliana Goumnerova, Mark W. Kieran, Karen J. Marcus, Mohammed A. Fouda

Publikováno v: Child's Nervous System. 36:291-296

To demonstrate the paradigm shift in management strategies of pediatric craniopharyngioma at our institution over the past six decades. Retrospective analysis of all pediatric patients with craniopharyngioma treated at Boston Children’s Hospital be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea02548dd7967870d685e3262629d671
https://doi.org/10.1007/s00381-019-04294-x

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Phase I study of gene-mediated cytotoxic immunotherapy with AdV-tk as adjuvant to surgery and radiation for pediatric malignant glioma and recurrent ependymoma

Autor: Liliana Goumnerova, Stewart Goldman, Rishi Lulla, Estuardo Aguilar-Cordova, Susan N. Chi, Peter E. Manley, Andrea G. Manzanera, Mark W. Kieran, Tadanori Tomita, Karen J. Marcus, Laura K. Aguilar, Arthur J DiPatri

Publikováno v: Neuro-Oncology. 21:537-546

Background Gene-mediated cytotoxic immunotherapy (GMCI) is a tumor-specific immune stimulatory strategy implemented through local delivery of aglatimagene besadenovec (AdV-tk) followed by anti-herpetic prodrug. GMCI induces T-cell dependent tumor imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0eb64f64c50a164d5c836477183038
https://doi.org/10.1093/neuonc/noy202

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Pain affect disrupted in children with posterior cerebellar tumor resection

Autor: Peter E. Manley, Christine Chordas, Julie Rosner, Katie E. Silva, Nicole J. Ullrich, Eric A. Moulton

Publikováno v: Annals of Clinical and Translational Neurology

Objectives Damage to the posterior cerebellum can cause affective deficits in patients. In adults, cerebellar infarcts result in thermal hyperalgesia and affect descending modulation of pain. This study evaluated the effect of resection of low‐grad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2268c1a9668a654e7b5dd4d710e6fc0e
https://doi.org/10.1002/acn3.709

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Novel predictive scoring system for morbid hypothalamic obesity in patients with pediatric craniopharyngioma

Autor: Mohammed A, Fouda, David, Zurakowski, R Michael, Scott, Karen J, Marcus, Peter E, Manley, Nicole J, Ullrich, Laurie E, Cohen, Liliana C, Goumnerova

Publikováno v: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 37(2)

To identify the independent risk factors for developing morbid hypothalamic obesity, to propose a predictive scoring system for morbid hypothalamic obesity, and to propose an algorithm for management in order to minimize the risk of developing morbid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f1886e8404e0987eb2d8db3c38e9ac58
https://pubmed.ncbi.nlm.nih.gov/32888069

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