Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Peter E. Hicks"'
1
Alfuzosin, a selective α1-adrenoceptor antagonist in the lower urinary tract
Autor: E. Gautier, S.Z. Langer, Hans Schoemaker, Philippe Manoury, Peter E. Hicks, F Lefèvre-Borg, J. Lechaire, F. Pierre, S.E. O'Connor, C. Pimoule
Publikováno v: British Journal of Pharmacology. 109:1282-1289
1. Phenylephrine-induced contractions of rabbit isolated trigone and urethra were antagonized in a competitive manner by alfuzosin (pA2 7.44 and 7.30, respectively) and prazosin. 2. The characteristics of [3H]-prazosin binding to human prostatic aden
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f218134e15385fcad77c43a784239f6
https://doi.org/10.1111/j.1476-5381.1993.tb13762.x
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2
Vascular Calcium Overload Produced by Administration of Vitamin D3 and Nicotine in Rats. Changes in Tissue Calcium Levels, Blood Pressure, and Pressor Responses to Electrical Stimulation or Norepinephrine in Vivo
Autor: Eric Thorin, Peter E. Hicks, Jean A. Martin, Daniel Henrion, L. Oster, Christine Capdeville, Nathalie Thorin-Trescases, Jean M. Chillon, Jeffrey Atkinson
Publikováno v: Journal of Cardiovascular Pharmacology. 16:257-266
Increased calcium content of cardiovascular tissues is a phenomenon common to natural aging and various pathological conditions such as hypertension and arteriosclerosis. We investigated an accelerated cardiovascular calcium overload model in young r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dce03f86160fa28400b4622ab8bdcea
https://doi.org/10.1097/00005344-199008000-00012
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6
5HT-receptor antagonist properties of SCH 23390 in vascular smooth muscle and brain
Autor: Salomon Z. Langer, Peter E. Hicks, Hans Schoemaker
Publikováno v: European Journal of Pharmacology. 105:339-342
The dopamine D1-receptor antagonist SCH 23390 was a potent competitive antagonist of 5HT-induced vasoconstriction in the isolated perfused rat tail artery preparation (pA2 8.17) but a very weak antagonist of phenylephrine-induced responses (pA2 5.94)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15fab3c420f69d04f1780c42880e4eb
https://doi.org/10.1016/0014-2999(84)90628-9
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7
Studies on the Mechanisms of the Development of Tolerance to the Hypotensive Effects of Fenoldopam in Rats
Autor: Françoise Lefèvre-Borg, Icilio Cavero, Janine Lorrain, Peter E. Hicks, Jacqueline Lechaire, Chantal Thiry
Publikováno v: Journal of Cardiovascular Pharmacology. 11:444-455
In pentobarbital-anesthetized rats prepared for hemodynamic measurements with Doppler flow probes, intravenous (i.v.) infusions of fenoldopam (2.5 - 160.0 micrograms/kg/min during 15 min) decreased mean carotid artery blood pressure, total peripheral
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898c50f6e16bb8dadefab6d0b2c9d05d
https://doi.org/10.1097/00005344-198804000-00010
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8
Antagonism by tetrahydro-β-carboline of the vasoconstrictor responses to tryptamine in rat tail arteries
Autor: Salomon Z. Langer, Peter E. Hicks
Publikováno v: European Journal of Pharmacology. 96:145-149
Tryptamine and 5-HT mediate vasoconstriction in the isolated perfused rat tail artery. These agonists were differentiated by the classical serotonin receptor antagonists methysergide and ketanserin which were significantly more potent against 5-HT-in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74770dd82d11cec02d74cdc2d5dd140
https://doi.org/10.1016/0014-2999(83)90543-5
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9
Effect of acidosis on α1- and α2-adrenoceptor-mediated vasoconstrictor responses in isolated arteries
Autor: Salomon Z. Langer, Iain C. Medgett, Peter E. Hicks
Publikováno v: European Journal of Pharmacology. 135:443-447
We have investigated the effect of reducing the pH (from 7.5 to 7.0 by addition of HCl) on vasoconstrictor responses to noradrenaline in cat middle cerebral artery (in which responses are mediated almost entirely by alpha 2-adrenoceptors) and in rabb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f720bc1fe536243b0c3334bc08fcb7ad
https://doi.org/10.1016/0014-2999(87)90698-4
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10
Dopamine preferentially stimulates postsynaptic α2-adrenoceptors in the femoral vascular bed, but α1-adrenoceptors in the renal vascular bed of the anaesthetised dog
Autor: Peter E. Hicks, Salomon Z. Langer, Nicole Duval
Publikováno v: European Journal of Pharmacology. 108:265-272
The decrease in blood flow in response to dopamine (DA) injected intraarterially (i.a.) into the femoral or renal vascular beds was examined in the anaesthetised dog. DA or noradrenaline (NA) were 10 times more potent as vasoconstrictor agents in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f4fe8175046917a531ac270ecd6201
https://doi.org/10.1016/0014-2999(85)90448-0
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