Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Peter E Sudbery"'
Autor:
Jamie A Greig, Ian M Sudbery, Jonathan P Richardson, Julian R Naglik, Yue Wang, Peter E Sudbery
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004630 (2015)
The opportunistic human fungal pathogen, Candida albicans, undergoes morphological and transcriptional adaptation in the switch from commensalism to pathogenicity. Although previous gene-knockout studies have identified many factors involved in this
Externí odkaz:
https://doaj.org/article/846d535c67e340c5a4c64b412dfb7735
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
The chromosome complement of the human fungal pathogen Candida albicans is unusually unstable, suggesting that the process of nuclear division is error prone. The Cdc14 phosphatase plays a key role in organising the intricate choreography of mitosis
Publikováno v:
The Journal of Cell Biology
In the development of hyphal germ tubes of Candida albicans, a band of septin forms at the base of the germ tube (basal septin band). Later, a septin ring forms, which organizes the first septum within the germ tube (septin ring). We have investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d607fe0489683d4b2724c9d599d1f3cb
The chromosome complement of the human fungal pathogenCandida albicansis unusually unstable, suggesting that process of nuclear division is error prone. The Cdc14 phosphatase plays a key role in organising the intricate choreography of mitosis and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c935b58c2258fc02d674948a55fb18
Autor:
Peter E. Sudbery
Publikováno v:
Nature Reviews Microbiology. 9:737-748
The fungus Candida albicans is often a benign member of the mucosal flora; however, it commonly causes mucosal disease with substantial morbidity and in vulnerable patients it causes life-threatening bloodstream infections. A striking feature of its
Publikováno v:
Fungal Biology. 115:547-556
Fungi can grow in a variety of growth forms: yeast, pseudohyphae and hyphae. The human fungal pathogen Candida albicans can grow in all three of these forms. In this fungus, hyphal growth is distinguished by the presence of a Spitzenkörper-like stru
Autor:
Laura A. Jones, Peter E. Sudbery
Publikováno v:
Eukaryotic Cell. 9:1455-1465
During the extreme polarized growth of fungal hyphae, secretory vesicles are thought to accumulate in a subapical region called the Spitzenkörper. The human fungal pathogen Candida albicans can grow in a budding yeast or hyphal form. When it grows a
Publikováno v:
PROTEOMICS. 18:1700278
Stable isotope labelling by amino acids in cell culture (SILAC) in conjunction with MS analysis is a sensitive and reliable technique for quantifying relative differences in protein abundance and posttranslational modifications between cell populatio
Autor:
Peter E. Sudbery, Martin H. Thornhill, Sarah E. W. Grubb, Stephen P. Saville, Craig Murdoch, Jose L. Lopez-Ribot
Publikováno v:
Infection and Immunity. 77:3872-3878
Candida albicans is a commensal organism that under certain circumstances can become pathogenic. During systemic infection C. albicans is disseminated via the circulation to distant organs, where it causes multiple organ failure. Despite the severity
Autor:
Marek S. Skrzypek, Piet W. J. de Groot, Mary E. Logue, Steven Bates, David Harris, Neil A. R. Gow, Christina A. Cuomo, Joseph Heitman, Michael A. Quail, Lois L. Hoyer, Michael P. H. Stumpf, Manfred Grabherr, Matthew Berriman, Gavin Sherlock, Bernhard Hube, Esther Rheinbay, Bruce W. Birren, Kevin A. T. Silverstein, Michael C. Lorenz, David R. Soll, Alistair J. P. Brown, Michael F. Lin, Sascha Brunke, Jennifer L. Reedy, Maria C. Santos, Geraldine Butler, Anja Forche, Aaron M. Neiman, Sharadha Sakthikumar, Janet Quinn, Ronny Martin, Manuel A. S. Santos, Carol A. Munro, Martha B. Arnaud, Rodney Staggs, Thyagarajan Srikantha, Florian F. Schmitzberger, Frans M. Klis, Peter E. Sudbery, Elissavet Nikolaou, Chinnappa D. Kodira, Maria C. Costanzo, Manolis Kellis, Judith Berman, Nicola Lennard, Ian Stansfield, David A. Fitzpatrick, Prachi Shah, Qiandong Zeng, Matthew D. Rasmussen, Ino Agrafioti
Publikováno v:
Nature
Nature, 459(7247), 657-662. Nature Publishing Group
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature, 459(7247), 657-662. Nature Publishing Group
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Candida species are the most common cause of opportunistic fungal infection worldwide. Here we report the genome sequences of six Candida species and compare these and related pathogens and non-pathogens. There are significant expansions of cell wall