Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Peter E O'Donnell"'
Autor:
Peter E O'Donnell, Xiu Zhen Ye, Melissa A DeChellis, Vannessa M Davis, Sheng Zhong Duan, Richard M Mortensen, David S Milstone
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160636 (2016)
Peroxisome proliferator activated receptor gamma (PPARγ) is a pleiotropic ligand activated transcription factor that acts in several tissues to regulate adipocyte differentiation, lipid metabolism, insulin sensitivity and glucose homeostasis. PPARγ
Externí odkaz:
https://doaj.org/article/fe1360a1884649e6b99b5b554bfbab27
Publikováno v:
Journal of Leukocyte Biology. 83:1423-1430
Neutrophils play an important role in immune complex (IC)-mediated diseases, but the mechanisms underlying their recruitment to sites of IC deposition remain largely undefined. Fur- thermore, neutrophils encounter cytokines that prime their effector
Autor:
David S. Milstone, Karen S. Moulton, Ying Yu, Joyce Bischoff, Peter E. O'Donnell, Vannessa M. Davis, Mohamed K. Khan, Eileen Boye, Sabrina Vineberg
Publikováno v:
Proceedings of the National Academy of Sciences. 101:8005-8010
Endostatin, a 20-kDa fragment of collagen XVIII, is a potent angiogenesis inhibitor. E-selectin, an inducible leukocyte adhesion molecule specifically expressed by endothelial cells, has also been implicated in angiogenesis. By usingin vivo,ex vivo,
Autor:
George Stavrakis, Sara Knight, Ling Xiao, Ulrich H. von Andrian, Peter E. O'Donnell, Tracy Stokol, Tanya N. Mayadas, Marina Botto
Publikováno v:
The Journal of Experimental Medicine
Inflammation induced by circulating immunoglobulin G–immune complexes (ICs) characterizes many immune-mediated diseases. In this work, the molecular requirements for the deposition of circulating ICs and subsequent acute leukocyte recruitment in mi
Autor:
Rakesh K. Jain, David S. Milstone, Richard C. Padgett, Michael A. Gimbrone, Dai Fukumura, Robert J. Melder, Oscar J. Benavidez, Vannessa M. Davis, Wayne L. Monsky, Peter E. O'Donnell
Publikováno v:
Microcirculation. 5:153-171
Objective:Previous work indicated that E-selectin mediates transient interactions between leukocytes and cytokine-activated endothelium in vitro. Here we examine the role of E-selectin in blood leukocyte interactions with microvascular endothelium in
Autor:
DAVID S MILSTONE, D A I FUKUMURA, RICHARD C PADGETT, PETER E O'DONNELL, VANNESSA M DAVIS, OSCAR J BENAVIDEZ, WAYNE L MONSKY, ROBERT J MELDER, RAKESH K JAIN, MICHAEL A GIMBRONE
Publikováno v:
Microcirculation. 5:153-171
Autor:
Peter E. O'Donnell, George Stavrakis, David S. Milstone, Richard M. Mortensen, Vannessa M. Davis
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 80(6)
Leukocyte recruitment during inflammation is specified, in part, by the spatial distribution and temporal regulation of endothelial adhesion molecules. In this study we investigated the developmental onset of E-selectin and intercellular adhesion mol
Autor:
Karen S. Moulton, Vannessa M. Davis, Ying Yu, Eileen Boye, Joyce Bischoff, Sabrina Vineberg, Peter E. O'Donnell, Mohamed K. Khan, David S. Milstone
Publikováno v:
Cardiovascular Pathology. 13:8-9
Autor:
David S. Milstone, C. Iehlé, Cécile Vernochet, N. Belmonte, Blaine W. Phillips, Richard M. Mortensen, Gérard Ailhaud, Christian Dani, Brigitte Wdziekonski, Ez-Zoubir Amri, Phi Villageois, Peter E. O'Donnell
Publikováno v:
FEBS Letters. (1-2):94-98
Peroxisome proliferator-activated receptor (PPAR) gamma was shown to be required for adipocyte formation both in vivo and in vitro. However, the role of PPARgamma in the initial steps of adipose cell development was not distinguished from its role in