Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Peter E Crossen"'
Autor:
Peter E. Crossen
Publikováno v:
Clinical Genetics. 8:218-222
The centromeric banding pattern of chromosomes 19 exhibited considerable variation. The variants were present in the majority of cells from an individual and consisted of additional dark-staining areas. There was no abnormal phenotypic effect associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7e25c04670e56423b080fa80cf7009
https://doi.org/10.1111/j.1399-0004.1975.tb01497.x
https://doi.org/10.1111/j.1399-0004.1975.tb01497.x
Publikováno v:
Cancer Genetics and Cytogenetics. 113:126-133
A case of acute myeloid leukemia (M2) with double minute chromosomes and complex karyotypic abnormalities was analyzed cytogenetically and molecularly. Comparative genomic hybridization (CGH) showed that the 8q24 region that contains the MYC oncogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d8a38e65bffaab80af25c1d37b523f
https://doi.org/10.1016/s0165-4608(99)00018-7
https://doi.org/10.1016/s0165-4608(99)00018-7
Publikováno v:
Cancer Genetics and Cytogenetics. 112:144-148
We have characterized the double minute chromosomes in a case of acute myeloid leukemia (AML). Southern blot analysis showed that the C-MYC was amplified. Further analysis with probes located both 3' and 5' of MYC indicated that the amplicon was at l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aa5c5b6bba90f15056a5abcd6d3fd7
https://doi.org/10.1016/s0165-4608(98)00260-x
https://doi.org/10.1016/s0165-4608(98)00260-x
Autor:
Mary J. Morrison, Peter E. Crossen
Publikováno v:
Mechanisms of Ageing and Development. 88:61-65
We studied the frequency of an Sst I polymorphism of the ETS-I oncogene in 122 elderly subjects (mean age 78.14 years) and 115 teenagers (mean age 16.9 years). No difference in the frequency of the three genotypes (C1C1, C1C2, C2C2) was found between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f7cc54f59a6c10ade4afbc9c26c3da
https://doi.org/10.1016/0047-6374(96)01721-6
https://doi.org/10.1016/0047-6374(96)01721-6
Autor:
Peter E. Crossen, Mary J. Morrison
Publikováno v:
Leukemia Research. 23:251-253
We examined the methylation status of the third exon of the MYC oncogene in 39 patients with B-cell malignancies. DNA was digested with MspI plus EcoRI or HpaII plus EcoRI and hybridised with a probe specific for the third exon of MYC. Thirty four pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361c630f9054514e5138f88c1ba48b9f
https://doi.org/10.1016/s0145-2126(98)00167-2
https://doi.org/10.1016/s0145-2126(98)00167-2
Publikováno v:
British Journal of Cancer
We studied 100 patients with non-Hodgkin's lymphoma, 44 patients with Hodgkin's disease and 100 controls for the prevalence of the EcoRI restriction fragment polymorphism of the L-myc oncogene. No difference in the frequency of the three genotypes (L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7d7075594cec7df339a41d6c427209
http://europepmc.org/articles/PMC1968797
http://europepmc.org/articles/PMC1968797
Publikováno v:
Genes, Chromosomes and Cancer. 8:60-62
The t(14;19) is a recurring translocation found in a small number of cases of chronic B-cell leukemia (CLL). We have cloned and sequenced the breakpoint in a patient with a t(14;19) and shown that the breakpoint on chromosome 14 occurred in the Cμ s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b805b169be35c39d7ac8ac3b21703b3
https://doi.org/10.1002/gcc.2870080110
https://doi.org/10.1002/gcc.2870080110
Publikováno v:
Cancer genetics and cytogenetics. 128(2)
Cytogenetic analysis of a patient with non-Hodgkin lymphoma revealed the following karyotype: 49,XXX,t(2;14)(q21;q32),+4,+8,del(13)(q14q21). Southern blot analysis with an Ig region probe showed non-productive rearrangements indicative of a transloca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f307dd3bd35f5653e4971215783d22e
https://pubmed.ncbi.nlm.nih.gov/11463452
https://pubmed.ncbi.nlm.nih.gov/11463452
Publikováno v:
Cancer Genetics and Cytogenetics. 48:255-257
Cytogenetic analysis of bone marow cells from a 53-year-old man with acute nonlymphocytic leukemia (FAB-M4) revealed a t(2;14)(q23;q32.3) as the sole cytogenetic abnormality. This is the first report of a t(2;14)(q23;q32.3) as the sole abnormality in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3020d75a9cbd30e7f9b78a88eec4c3
https://doi.org/10.1016/0165-4608(90)90128-w
https://doi.org/10.1016/0165-4608(90)90128-w
Autor:
Peter E. Crossen, Mary J. Morrison
Publikováno v:
Leukemialymphoma. 31(5-6)
Analysis of the organisation of the Cmu-switch region of the immunoglobulin heavy chain locus in B-lymphocytes from 80 patients with chronic B-cell leukemia revealed 25 patients with abnormal rearrangements that could not be explained by the normal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee7b3b8d39ae0f5629ba46c85c38f52
https://pubmed.ncbi.nlm.nih.gov/9922046
https://pubmed.ncbi.nlm.nih.gov/9922046