Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Peter E, Keipert"'
Autor:
Peter E. Keipert
Publikováno v:
Blood Substitutes and Oxygen Biotherapeutics ISBN: 9783030959746
Advances in Experimental Medicine and Biology ISBN: 9783319552293
Advances in Experimental Medicine and Biology ISBN: 9783319552293
Historically, hemoglobin-based oxygen carriers (HBOCs) were being developed as “blood substitutes,” despite their transient circulatory half-life (~ 24 h) vs. transfused red blood cells (RBCs). More recently, HBOC commercial development focused o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7125cee9f6544f5fa57afddd371eec67
https://doi.org/10.1007/978-3-030-95975-3_41
https://doi.org/10.1007/978-3-030-95975-3_41
Autor:
Peter E. Keipert
Publikováno v:
Blood Substitutes and Oxygen Biotherapeutics ISBN: 9783030959746
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f329e1fe6691f1bd6ea5e2c179c04508
https://doi.org/10.1007/978-3-030-95975-3_32
https://doi.org/10.1007/978-3-030-95975-3_32
Autor:
Peter E, Keipert
Publikováno v:
Advances in experimental medicine and biology. 977
Historically, hemoglobin-based oxygen carriers (HBOCs) were being developed as "blood substitutes," despite their transient circulatory half-life (~ 24 h) vs. transfused red blood cells (RBCs). More recently, HBOC commercial development focused on "o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fdd7fe90298eb479f935f4f9519e6ec5
https://pubmed.ncbi.nlm.nih.gov/28685464
https://pubmed.ncbi.nlm.nih.gov/28685464
Autor:
Peter E, Keipert
Publikováno v:
Advances in experimental medicine and biology. 923
MP4CO, developed by Sangart Inc. (San Diego, CA), is a pegylated human hemoglobin-based carbon monoxide (CO) delivery agent and oxygen therapeutic that has shown potential to prevent and reverse red cell sickling. A double blind, comparator controlle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2eb337db25ed5642e74b0c5841e9b3bb
https://pubmed.ncbi.nlm.nih.gov/27526120
https://pubmed.ncbi.nlm.nih.gov/27526120
Autor:
Philippe, van der Linden, Tadeusz S, Gazdzik, David, Jahoda, René J, Heylen, Jan C, Skowronski, David, Pellar, Ivo, Kofranek, Andrzej Z, Górecki, Bengt, Fagrell, Peter E, Keipert, Yun J, Hardiman, Howard, Levy, Rose-Marie, Rörqvist
Publikováno v:
Anesthesia & Analgesia. 112:759-773
MP4OX (oxygenated polyethylene glycol-modified hemoglobin) is a novel oxygen therapeutic agent specifically developed to perfuse and oxygenate tissue at risk for ischemia and hypoxia. In this study, we investigated the ability of MP4OX to treat hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001dba85889640035c2ebbdbef61f199
https://doi.org/10.1213/ane.0b013e31820c7b5f
https://doi.org/10.1213/ane.0b013e31820c7b5f
Autor:
Peter E. Keipert
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783319388083
MP4CO, developed by Sangart Inc. (San Diego, CA), is a pegylated human hemoglobin-based carbon monoxide (CO) delivery agent and oxygen therapeutic that has shown potential to prevent and reverse red cell sickling. A double blind, comparator controlle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1118786db4bc6e86d5c2ede2d65c0dfb
https://doi.org/10.1007/978-3-319-38810-6_3
https://doi.org/10.1007/978-3-319-38810-6_3
Autor:
N. Simon Faithfull, Steven E. Hill, Bruce J. Leone, Peter E. Keipert, Mark F. Newman, Kathy E. Flaim
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 16:555-560
Objective: To assess tolerance and preliminary efficacy of a perfluorocarbon emulsion (AF0144) used with acute normovolemic hemodilution to reduce allogeneic blood transfusion for patients undergoing coronary artery bypass graft (CABG) surgery with c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b92ec988a1986c94167c8c59e4f3226
https://doi.org/10.1053/jcan.2002.126947
https://doi.org/10.1053/jcan.2002.126947
Publikováno v:
Anesthesiology. 93:1261-1270
Background Perfluorocarbon-based oxygen carriers have been proposed as an adjunct to autologous blood conservation techniques during elective surgery. To date, the effects of perfluorocarbon emulsions at the microcirculatory level have not been studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::def6852b03d24a3d289874ab19705f1c
https://doi.org/10.1097/00000542-200011000-00020
https://doi.org/10.1097/00000542-200011000-00020
Autor:
Phillip T. Leese, Robert J. Noveck, Jolene S. Shorr, Catherine M. Woods, Kathryn E. Flaim, Peter E. Keipert
Publikováno v:
Anesthesia & Analgesia. 91:804-811
Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76ecd421bdbc2119bf89959d185a41a
https://doi.org/10.1097/00000539-200010000-00008
https://doi.org/10.1097/00000539-200010000-00008
Autor:
Catherine M. Woods, Edward J. Shannon, Peter E. Keipert, Jolene S. Shorr, Phillip T. Leese, K. E. Flaim, Robert Noveck
Publikováno v:
Anesthesia & Analgesia. 91:812-822
Particle size distribution is a major determinant of particle clearance by the mononuclear phagocytic system and the potential for concomitant activation of resident macrophages. To test the safety of a second-generation perflubron-based emulsion (60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00f8d1c5564c3421c9bef6e38eea6af
https://doi.org/10.1097/00000539-200010000-00009
https://doi.org/10.1097/00000539-200010000-00009