Spontaneous Isolated Iliopsoas Tendon Tear in Elderly—Case Report and Review of Literature

Autor: Ramanan Rajakulasingam, Christine Azzopardi, Peter Dutton, David Beale, Rajesh Botchu

Publikováno v: Indian Journal of Radiology and Imaging, Vol 31, Iss 03, Pp 719-720 (2021)

Iliopsoas tendon tears are rare. These typically occur in young and can be associated with avulsion fractures of lesser trochanter. We report a case of full thickness rupture of iliopsoas tendon in 87-year-old male without avulsion of the lesser troc

Externí odkaz: https://doaj.org/article/5080daf41d834ce1a3895fed47ed5769

Design, analysis and reporting of multi-arm trials and strategies to address multiple testing

Autor: Bethan Copsey, Peter Dutton, Benjamin Speich, Karan Vadher, Douglas G. Altman, Sally Hopewell, Ayodele Odutayo, Corran Roberts, Dmitry Gryaznov, Matthias Briel, Paul Monk

Publikováno v: International journal of epidemiology. 49(3)

Background It is unclear how multiple treatment comparisons are managed in the analysis of multi-arm trials, particularly related to reducing type I (false positive) and type II errors (false negative). Methods We conducted a cohort study of clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdc9f0ccef6ad9c4db32b153e2f3c09
https://pubmed.ncbi.nlm.nih.gov/32176282

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

Autor: Evelyn Fessler, Sarah Briggs, Anita Sveen, Jan Paul Medema, Ian Tomlinson, Viktor H. Koelzer, Peter Dutton, Mauro Delorenzi, Martin D. Berger, Marco de Bruyn, Alessandro Lugli, Kay Lawson, Inti Zlobec, Dahmane Oukrif, Enric Domingo, Marco Novelli, Sergi Castellví-Bel, Rachel Kerr, Mark A. Glaire, Louis Vermeulen, Hans Morreau, Stine A. Danielsen, Sabine Tejpar, Luke Freeman-Mills, Jenifer Muñoz, Gerrit-Jan Liefers, Eleni Frangou, Hans W. Nijman, Arild Nesbakken, Emily Rayner, Tom van Wezel, David J. Kerr, Ragnhild A. Lothe, David N. Church, Arnoud Boot

Publikováno v: The lancet. Gastroenterology & hepatology, 1(3), 207-216. HANLEY & BELFUS-ELSEVIER INC
lancet. Gastroenterology & hepatology, 1(3), 207-216. Elsevier Limited

BACKGROUND: Precision cancer medicine depends on defining distinct tumour subgroups using biomarkers that may occur at very modest frequencies. One such subgroup comprises patients with exceptionally mutated (ultramutated) cancers caused by mutations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed325714ec36cf99837eca5d0a0ab25
https://doi.org/10.1016/s2468-1253(16)30014-0

Adequate SIRT activity dose is as important as adequate chemotherapy dose – Authors' reply

Autor: Peter Dutton, Guy van Hazel, Ricky A. Sharma, Julien Taieb, Navesh K. Sharma, Peter Gibbs, P S Virdee, Harpreet Wasan, Joanna Moschandreas, Jens Ricke

Publikováno v: Lancet Oncology. 18(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22acdb5d9d844b6c76e7835c28690f2
http://ora.ox.ac.uk/objects/uuid:

Analysis of phase II methodologies for single-arm clinical trials with multiple endpoints in rare cancers: An example in Ewing's sarcoma

Autor: Lucinda Billingham, Sharon Love, Peter Dutton, A B Hassan

Publikováno v: Statistical Methods in Medical Research

Trials run in either rare diseases, such as rare cancers, or rare sub-populations of common diseases are challenging in terms of identifying, recruiting and treating sufficient patients in a sensible period. Treatments for rare diseases are often des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2befc03a7e22eddb8ed19127bdfc350e
https://ora.ox.ac.uk/objects/uuid:49ec1b02-869b-4246-a122-314cd42ebd94