Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Peter Dromparis"'
Autor:
M. Buchko, Darren H. Freed, Jayan Nagendran, N. Aboelnazar, Sanaz Hatami, Peter Dromparis, Benjamin Adam, Sayed Himmat, Catherine J. Stewart
Publikováno v:
Transplantation Proceedings. 52:2941-2946
Background Normothermic ex vivo lung perfusion (EVLP) has been used successfully to evaluate and recondition marginal donor lungs; however, multiple barriers continue to prevent its widespread adoption. We sought to develop a common hospital ingredie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9873dbc4572b0d0e32eb595f7cf62656
https://doi.org/10.1016/j.transproceed.2020.05.007
https://doi.org/10.1016/j.transproceed.2020.05.007
Autor:
Bruno Saleme, Aristeidis E. Boukouris, Adam Kinnaird, Gopinath Sutendra, Evangelos D. Michelakis, Sotirios Zervopoulos, Vikram Gurtu, Peter Dromparis
Publikováno v:
Journal of Molecular Medicine. 98:1269-1278
The von Hippel-Lindau (VHL) protein binds and degrades hypoxia-inducible factors (HIF) hydroxylated by prolyl-hydroxylases under normoxia. Although originally described as a tumor suppressor, there is growing evidence that VHL may paradoxically promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f23c827e15ec162de0ceccd93cd6f9
https://doi.org/10.1007/s00109-020-01951-6
https://doi.org/10.1007/s00109-020-01951-6
Autor:
Sanaz Hatami, Sayed Himmat, Benjamin Adam, M. Buchko, Peter Dromparis, Jayan Nagendran, Darren H. Freed, Catherine J. Stewart
Publikováno v:
Transplantation Proceedings. 51:2022-2028
Background Extended periods of ex vivo lung perfusion (EVLP) lead to several inadvertent consequences including accumulation of lactate and increasing electrolyte concentrations in the perfusate. We sought to determine whether continuous hemodialysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d87ec434312d525d0def440ff7a995a
https://doi.org/10.1016/j.transproceed.2019.03.042
https://doi.org/10.1016/j.transproceed.2019.03.042
Autor:
Christopher W. White, Darren H. Freed, Sanaz Hatami, Michael Mengel, Almothana Alzamil, Sayed Himmat, Jayan Nagendran, Peter Dromparis, N. Aboelnazar
Publikováno v:
Artificial Organs. 42:271-279
Normothermic ex vivo lung perfusion (EVLP) is an evolving technology to evaluate function of donor lungs to determine suitability for transplantation. We hypothesize that hypoxic pulmonary vasoconstriction (HPV) during EVLP will provide a more sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::735624dc290eec0abff22e9d412ea8bb
https://doi.org/10.1111/aor.13017
https://doi.org/10.1111/aor.13017
Autor:
Silas Rotich, Peter Dromparis, Siegfried Wagner, Jessica G.Y. Luc, Sayed Himmat, Darren H. Freed, Sanaz Hatami, Jayan Nagendran, N. Aboelnazar, Michael Mengel, Christopher W. White, Benjamin Adam
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 19(4)
Ex vivo lung perfusion (EVLP) shows promise in ameliorating pretransplant acute lung injury (ALI) and expanding the donor organ pool, but the mechanisms of ex vivo repair remain poorly understood. We aimed to assess the utility of gene expression for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e626bd1e29fc9c1ab1c2ee558d1d9f6
https://pubmed.ncbi.nlm.nih.gov/30230229
https://pubmed.ncbi.nlm.nih.gov/30230229
Introduction: Non-muscle-invasive bladder cancer is the most expensive malignancy to treat. Current Canadian guidelines recommend repeat transurethral resection of bladder tumour (TURBT) within six weeks after initial resection of T1 high-grade (T1HG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b49f61feada6dd8a3c2e3c30b7361eb
https://europepmc.org/articles/PMC6114158/
https://europepmc.org/articles/PMC6114158/
Autor:
M. Buchko, Darren H. Freed, Catherine J. Stewart, Benjamin Adam, Sayed Himmat, Peter Dromparis, Jayan Nagendran, Sanaz Hatami
Publikováno v:
The Journal of Heart and Lung Transplantation. 38:S237-S238
Purpose Extended periods of ex vivo lung perfusion (EVLP) lead to several inadvertent consequences including accumulation of lactate and increasing electrolyte concentrations in the perfusate. Cellular perfusate based systems, such as the OCS Lung an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93a286f3f0e7241695f1f01d3dc8d53f
https://doi.org/10.1016/j.healun.2019.01.585
https://doi.org/10.1016/j.healun.2019.01.585
Autor:
Evangelos D. Michelakis, Steeve Provencher, Roxane Paulin, Alois Haromy, Vikram Gurtu, Peter Dromparis, Gopinath Sutendra, Sébastien Bonnet
Publikováno v:
Circulation Research. 116:56-69
Rationale: Right ventricular (RV) failure is a major cause of morbidity and mortality in pulmonary hypertension, but its mechanism remains unknown. Myocyte enhancer factor 2 (Mef2) has been implicated in RV development, regulating metabolic, contract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e4efffac7db0ec847fb50ddabf62e6
https://doi.org/10.1161/circresaha.115.303910
https://doi.org/10.1161/circresaha.115.303910
Autor:
N. Aboelnazar, Sayed Himmat, Jayan Nagendran, Sanaz Hatami, Ganghong Tian, Nobutoshi Matsumura, Mohamad S. Burhani, Jason R.B. Dyck, Christopher W. White, Peter Dromparis, Darren H. Freed, Michael Mengel
Background: Normothermic ex-vivo lung perfusion (EVLP) using positive pressure ventilation (PPV) and both acellular and red blood cell (RBC)-based perfusate solutions have increased the rate of donor organ utilization. We sought to determine whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174e24ab2510e062ee89a3dd4f0e0dce
https://nrc-publications.canada.ca/eng/view/object/?id=083c33db-489a-4e79-87b8-2599533b63d3
https://nrc-publications.canada.ca/eng/view/object/?id=083c33db-489a-4e79-87b8-2599533b63d3
Autor:
Sayed, Himmat, Almothana, Alzamil, Nader, Aboelnazar, Sanaz, Hatami, Christopher, White, Peter, Dromparis, Michael, Mengel, Darren, Freed, Jayan, Nagendran
Publikováno v:
Artificial organs. 42(3)
Normothermic ex vivo lung perfusion (EVLP) is an evolving technology to evaluate function of donor lungs to determine suitability for transplantation. We hypothesize that hypoxic pulmonary vasoconstriction (HPV) during EVLP will provide a more sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d565162b7f9c9c5ba7f2c93af9b9a772
https://pubmed.ncbi.nlm.nih.gov/29266272
https://pubmed.ncbi.nlm.nih.gov/29266272