Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter Dr. Hammann"'
Autor:
Peter Dr. Hammann, Gerhard Kretzschmar
Publikováno v:
Tetrahedron. 46:5603-5608
The title compound 1 reacts by cycloaddition with diazoalkanes 2a and 2b to pyrazolines 3a and 3b and with nitrones 5a and 5b to isoxazolidines 6a and 6b . Reaction of 1 with diazofluorene yields the cyclopropane adduct 4 . The reaction proceeds regi
Publikováno v:
The Journal of Antibiotics. 43:1431-1440
The synthesis and the biological activity of 34 acyl derivatives of elaiophylin (1) and 6 deglycosidation products were described. Especially the unsymmetric deglycosidation products 33, 38 and 40 and dimethyloctahydroelaiophylin (21) exhibited an ac
Publikováno v:
Journal of medicinal chemistry. 35(5)
The synthesis and the biological activity of C-1-reduced nigericin derivatives (nigericinols) are described and discussed. The dichloronigericinol 7 impressively demonstrated that the C-1 carboxylic acid moiety was not required for a distinct activit
Publikováno v:
The Journal of antibiotics. 44(7)
Autor:
Ralf Thiericke, H. Kluge, Peter Dr. Hammann, Susanne Grabley, Klaus Hütter, Joachim Wink, Axel Zeeck
Publikováno v:
The Journal of antibiotics. 44(6)
Autor:
Gerhard Kretzschmar, Peter Dr. Hammann, Frank Ditzel, Wolfgang Raether, Achim Kröger, Mária Kajtár-Peredy, Robert Dr Klein
Publikováno v:
HETEROCYCLES. 32:1471
The synthesis of the polyether subunits (8-11), starting from elaiophylin (1), as well as their biological properties, nmr spectra and conformational studies were described and discussed. Based upon the missing ability of potassium transport it was d
Publikováno v:
HETEROCYCLES. 31:1907
A reversible blocking of the C-29 hemiacetal in nigericin (1) was performed with LiBr in methanol to the acetal (6). Conversion of the carboxylic acid to the C-1 alcohol (7) and the ketone (9) and the subsequent deprotection yielded 8 and 10, respect