Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Peter Dogterom"'
Autor:
Uta Schilling, Jasper Dingemanse, Christine Voors‐Pette, Christel Romeijn, Peter Dogterom, Mike Ufer
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 5, Pp 886-890 (2020)
In vitro studies have indicated that the P2Y12 receptor antagonist selatogrel is a substrate of organic anion‐transporting‐polypeptide (OATP)1B1 and OATP1B3 that are known to mediate hepatic uptake. Selatogrel is primarily eliminated via the bili
Externí odkaz:
https://doaj.org/article/53d31f9b8acd4bc486c39d9fc5c19b73
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 5, Pp 440-444 (2019)
Clazosentan is a selective endothelin A receptor antagonist in development for the prevention and treatment of vasospasm postsubarachnoid hemorrhage. It is a substrate of organic anion‐transporting polypeptide 1B1/1B3 based on preclinical data. Thi
Externí odkaz:
https://doaj.org/article/23c1179858904f2a83775c42287f2132
Autor:
Nicholas P. France, Christopher Rubino, M. Courtney Safir, Mari Maurer, Tram Duong, Deepika Singamsetty, Khalid Abd‐Elaziz, Thomas Chou, Sethu Sankaranarayanan, Marieke Ettema, Rebecca Cosford, Peter Dogterom, Enchi Liu, Carrolee Barlow
Publikováno v:
Clinical Pharmacology in Drug Development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2df720e85f402bd4d993ab5caeaa059
https://doi.org/10.1002/cpdd.1256
https://doi.org/10.1002/cpdd.1256
Autor:
Peter Dogterom, Camille Omar Farouk Kamlin, Tim Morley, Naseem Amin, Brinley Jackson, Karl Heinz Weiss, Catherine Thompson, Yi-Jin Chiou
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 46:665-675
Wilson disease (WD) is an autosomal recessive inherited disorder of copper metabolism. Chelation of excessive copper is recommended but data on the pharmacokinetics of trientine are limited. The aim of this study was to compare the pharmacokinetics o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65724413145531119477f7e16e56badb
https://doi.org/10.1007/s13318-021-00704-1
https://doi.org/10.1007/s13318-021-00704-1
Autor:
Valérie Bourdès, Peter Dogterom, André Aleman, Pierre Parmantier, Damien Colas, Sighild Lemarchant, Sébastien Marie, Thomas Chou, Khalid Abd-Elaziz, Yann Godfrin
Publikováno v:
Neurology and therapy, 11(3), 1353-1374. SPRINGER LONDON LTD
Introduction This randomized, double-blind, placebo-controlled study in healthy volunteers assessed the safety, tolerability, and pharmacokinetics of single ascending doses of intravenously administered NX210-a linear peptide derived from subcommissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cb4536f5fad24f5267265555b1fac1
https://pubmed.ncbi.nlm.nih.gov/35779189
https://pubmed.ncbi.nlm.nih.gov/35779189
Autor:
Peter Dogterom, Uta Schilling, Jasper Dingemanse, Christel Romeijn, Mike Ufer, Christine Voors-Pette
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 5, Pp 886-890 (2020)
Clinical and Translational Science
Clinical and Translational Science
In vitro studies have indicated that the P2Y12 receptor antagonist selatogrel is a substrate of organic anion-transporting-polypeptide (OATP)1B1 and OATP1B3 that are known to mediate hepatic uptake. Selatogrel is primarily eliminated via the biliary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e580295ef64cf4708eac2b6b6d94a9b
https://doaj.org/article/53d31f9b8acd4bc486c39d9fc5c19b73
https://doaj.org/article/53d31f9b8acd4bc486c39d9fc5c19b73
Autor:
Christine Voors-Pette, Lionel Renaud, Martine Jandrot Perrus, Philippe Billiald, Peter Dogterom, Yannick Pletan, Kristell Lebozec, Matthias Machacek
Publikováno v:
Journal of Clinical Pharmacology
Glenzocimab (ACT017) is a humanized monoclonal antigen‐binding fragment (Fab) directed against the human platelet glycoprotein VI, a key receptor for collagen and fibrin that plays a major role in thrombus growth and stability. Glenzocimab is being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c9de63a928368ee11790cf751ae559
http://europepmc.org/articles/PMC7496554
http://europepmc.org/articles/PMC7496554
Autor:
Pauline Ferlan, Yannick Pletan, Philippe Billiald, Kristell Lebozec, Lionel Renaud, Gilles Avenard, Laurie Jullien, Matthias Machacek, Christine Voors-Pette, Martine Jandrot-Perrus, Olivier Favre-Bulle, Peter Dogterom
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 39:956-964
Objective— ACT017 is a novel, first in class, therapeutic antibody to platelet GPVI (glycoprotein VI) with potent and selective antiplatelet effects. This first-in-human, randomized, placebo-controlled phase 1 study was conducted to evaluate the sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784af44981e4b4e85aa7b6dd3bf67993
https://doi.org/10.1161/atvbaha.118.312314
https://doi.org/10.1161/atvbaha.118.312314
Publikováno v:
Drug Development and Industrial Pharmacy. 44:1481-1487
To assess the absolute bioavailability of 20 mEq magnesium lactate extended-release (ER) caplets and to assess the effect of food on the pharmacokinetics of these ER caplets.Magnesium in different salt forms is available as over-the-counter oral form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9f74c53fd9528375f001eac81aa484
https://doi.org/10.1080/03639045.2018.1464020
https://doi.org/10.1080/03639045.2018.1464020
Autor:
Justin Dennie, Abhijeet Jakate, Rik de Greef, Matthew D. Troyer, André M. M. Miltenburg, Timothy J. Carrothers, Robert Riesenberg, Peter Dogterom, Venkatesh Pilla Reddy, Robert L. Findling, Martin Johnson
Publikováno v:
Drug Design, Development and Therapy
Peter Dogterom,1 Robert Riesenberg,2 Rik de Greef,1 Justin Dennie,3 Martin Johnson,1 Venkatesh Pilla Reddy,1 André MM Miltenburg,1 Robert L Findling,4 Abhijeet Jakate,5 Timothy J Carrothers,5 Matthew D Troyer3 1Early Stage Development, Merck Sharp a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef62effda0deea8e41fc2a88e39eb1b
https://www.dovepress.com/asenapine-pharmacokinetics-and-tolerability-in-a-pediatric-population-peer-reviewed-article-DDDT
https://www.dovepress.com/asenapine-pharmacokinetics-and-tolerability-in-a-pediatric-population-peer-reviewed-article-DDDT