Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Peter DelNero"'
Autor:
Emily Hallgren, Ramey Moore, Britni L. Ayers, Rachel S. Purvis, Gwendolyn Bryant-Smith, Peter DelNero, Pearl A. McElfish
Publikováno v:
Journal of Cancer Survivorship.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bfeb2d1c2b52146cb6f550b8c23bd19
https://doi.org/10.1007/s11764-023-01344-x
https://doi.org/10.1007/s11764-023-01344-x
Autor:
Shariq Madha, Caroline A. Lewis, Peter DelNero, Pei-Yun Tsai, Min-Sik Lee, Frederick R. Roberts, Ramesh A. Shivdasani, Clary B. Clish, Insia Naqvi, Kim C. Honselmann, Sergey Naumenko, Meeta Mistry, Mari Mino-Kenudson, Ashley Adler, Nada Y. Kalaany, Thomas Hank, Unmesh Jadhav, Vicente Morales Oyarvide, Daniel S. Hitchcock
Publikováno v:
Proc Natl Acad Sci U S A
Pancreatic ductal adenocarcinoma (PDA) is a lethal, therapy-resistant cancer that thrives in a highly desmoplastic, nutrient-deprived microenvironment. Several studies investigated the effects of depriving PDA of either glucose or glutamine alone. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98f45738b11f243c4ff828aa47feeea
https://doi.org/10.1073/pnas.2003014118
https://doi.org/10.1073/pnas.2003014118
Patient-derived culture models enable assessment of drug sensitivity and can connect personalized genomics with therapeutic options. However, their clinical translation is constrained by limited fidelity. We outline how the physical microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47950974ea1d38b0f1e5321a64361430
https://europepmc.org/articles/PMC5990021/
https://europepmc.org/articles/PMC5990021/
Autor:
Brian J. Kwee, Scott S. Verbridge, Maureen E. Lane, Peter DelNero, Barbara L. Hempstead, Pouneh Kermani, Claudia Fischbach, Abraham D. Stroock
Publikováno v:
Biomaterials. 55:110-118
Oxygen status and tissue dimensionality are critical determinants of tumor angiogenesis, a hallmark of cancer and an enduring target for therapeutic intervention. However, it is unclear how these microenvironmental conditions interact to promote neov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a4891e45cb52516605792decdb9502
https://doi.org/10.1016/j.biomaterials.2015.03.035
https://doi.org/10.1016/j.biomaterials.2015.03.035
Autor:
Peter DelNero
Publikováno v:
Michigan Journal of Community Service Learning. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f14467dcee27bb1e7c22db2d4e2a6af8
https://doi.org/10.3998/mjcsloa.3239521.0024.109
https://doi.org/10.3998/mjcsloa.3239521.0024.109
Autor:
Peter DelNero, Anirikh Chakrabarti, Abraham D. Stroock, Jeffrey D. Varner, Brian J. Kwee, Scott S. Verbridge, Claudia Fischbach
Publikováno v:
Journal of Biomedical Materials Research Part A. 101:2948-2956
Both physiological and pathological tissue remodeling (e.g., during wound healing and cancer, respectively) require new blood vessel formation via angiogenesis, but the underlying microenvironmental mechanisms remain poorly defined due in part to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::887c861c97867ee5b7b588f86e89f0a3
https://doi.org/10.1002/jbm.a.34587
https://doi.org/10.1002/jbm.a.34587
Microengineered tumor models: insights & opportunities from a physical sciences-oncology perspective
Publikováno v:
Biomedical Microdevices. 15:583-593
Prevailing evidence has established the fundamental role of microenvironmental conditions in tumorigenesis. However, the ability to identify, interrupt, and translate the underlying cellular and molecular mechanisms into meaningful therapies remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edff942b8f8425e25315a02c9365b26
https://doi.org/10.1007/s10544-013-9763-y
https://doi.org/10.1007/s10544-013-9763-y
Autor:
Peter, DelNero, Claudia, Fischbach
Publikováno v:
Nature materials
The profound metabolic reprogramming that occurs in cancer cells has been investigated primarily in two-dimensional cell cultures, which fail to recapitulate spatial aspects of cell-to-cell interactions as well as tissue gradients present in three-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1830e8e6b2633e8b372e574392dc1745
https://pubmed.ncbi.nlm.nih.gov/26595121
https://pubmed.ncbi.nlm.nih.gov/26595121
Autor:
Claudia Fischbach, Peter DelNero
Publikováno v:
Nature Materials. 15:138-139
A spool-and-ribbon cell-culture approach provides quick and easy access to the interior of engineered tumours for the analysis of cell responses to molecular gradients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd1755cdbaee3ceef21ec4fc77615431
https://doi.org/10.1038/nmat4549
https://doi.org/10.1038/nmat4549
Publikováno v:
Advanced drug delivery reviews.
Tumor-stroma interactions have emerged as critical determinants of drug efficacy. However, the underlying biological and physicochemical mechanisms by which the microenvironment regulates therapeutic response remain unclear, due in part to a lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5462735ddebad8c9e83adca59f3a283
https://pubmed.ncbi.nlm.nih.gov/24309015
https://pubmed.ncbi.nlm.nih.gov/24309015