Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Peter DelNero"'
Autor:
Nathanael B. Stanley, Todd Burus, Debora L. Oh, Calvin P. Tribby, Christopher McNair, Peter DelNero, Katherine Y. Tossas
Publikováno v:
Preventive Oncology & Epidemiology, Vol 3, Iss 1 (2025)
Background: NCI-Designated Cancer Centers must identify their catchment areas and address cancer burden through research and community engagement, highlighting the role of catchment area data experts. Few studies evaluate roles, needs, and opportunit
Externí odkaz:
https://doaj.org/article/a1c8d2753b274dbd9ed170f0fb30a166
Autor:
Emily Hallgren, Ramey Moore, Britni L. Ayers, Rachel S. Purvis, Gwendolyn Bryant-Smith, Peter DelNero, Pearl A. McElfish
Publikováno v:
Journal of Cancer Survivorship.
Autor:
Shariq Madha, Caroline A. Lewis, Peter DelNero, Pei-Yun Tsai, Min-Sik Lee, Frederick R. Roberts, Ramesh A. Shivdasani, Clary B. Clish, Insia Naqvi, Kim C. Honselmann, Sergey Naumenko, Meeta Mistry, Mari Mino-Kenudson, Ashley Adler, Nada Y. Kalaany, Thomas Hank, Unmesh Jadhav, Vicente Morales Oyarvide, Daniel S. Hitchcock
Publikováno v:
Proc Natl Acad Sci U S A
Pancreatic ductal adenocarcinoma (PDA) is a lethal, therapy-resistant cancer that thrives in a highly desmoplastic, nutrient-deprived microenvironment. Several studies investigated the effects of depriving PDA of either glucose or glutamine alone. Ho
Patient-derived culture models enable assessment of drug sensitivity and can connect personalized genomics with therapeutic options. However, their clinical translation is constrained by limited fidelity. We outline how the physical microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47950974ea1d38b0f1e5321a64361430
https://europepmc.org/articles/PMC5990021/
https://europepmc.org/articles/PMC5990021/
Autor:
Brian J. Kwee, Scott S. Verbridge, Maureen E. Lane, Peter DelNero, Barbara L. Hempstead, Pouneh Kermani, Claudia Fischbach, Abraham D. Stroock
Publikováno v:
Biomaterials. 55:110-118
Oxygen status and tissue dimensionality are critical determinants of tumor angiogenesis, a hallmark of cancer and an enduring target for therapeutic intervention. However, it is unclear how these microenvironmental conditions interact to promote neov
Autor:
Peter DelNero
Publikováno v:
Michigan Journal of Community Service Learning. 24
Autor:
Peter DelNero, Anirikh Chakrabarti, Abraham D. Stroock, Jeffrey D. Varner, Brian J. Kwee, Scott S. Verbridge, Claudia Fischbach
Publikováno v:
Journal of Biomedical Materials Research Part A. 101:2948-2956
Both physiological and pathological tissue remodeling (e.g., during wound healing and cancer, respectively) require new blood vessel formation via angiogenesis, but the underlying microenvironmental mechanisms remain poorly defined due in part to the
Microengineered tumor models: insights & opportunities from a physical sciences-oncology perspective
Publikováno v:
Biomedical Microdevices. 15:583-593
Prevailing evidence has established the fundamental role of microenvironmental conditions in tumorigenesis. However, the ability to identify, interrupt, and translate the underlying cellular and molecular mechanisms into meaningful therapies remains
Autor:
Peter, DelNero, Claudia, Fischbach
Publikováno v:
Nature materials
The profound metabolic reprogramming that occurs in cancer cells has been investigated primarily in two-dimensional cell cultures, which fail to recapitulate spatial aspects of cell-to-cell interactions as well as tissue gradients present in three-di
Autor:
Claudia Fischbach, Peter DelNero
Publikováno v:
Nature Materials. 15:138-139
A spool-and-ribbon cell-culture approach provides quick and easy access to the interior of engineered tumours for the analysis of cell responses to molecular gradients.