Výsledky vyhledávání - "Peter Deetjen"

ICln Ion Channel Splice Variants in Caenorhabditis elegans

Autor: Markus Paulmichl, Martin Jakab, Martin Gschwentner, Johann G. Danzl, Jakob Rudzki, Florian Lang, Markus Ritter, Johannes Fürst, Peter Deetjen, Elke Scandella, Bernhard Oehl, Matthias König

Publikováno v: Journal of Biological Chemistry. 277:4435-4445

ICln is an ion channel identified by expression cloning using a cDNA library from Madin-Darby canine kidney cells. In all organisms tested so far, only one transcript for the ICln protein could be identified. Here we show that two splice variants of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb86581c666d8bbb8b94dd548355bd4c
https://doi.org/10.1074/jbc.m107372200

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Na+/H+Exchangers: Linking Osmotic Dysequilibrium to Modified Cell Function

Autor: Sabine Chwatal, Ewald Wöll, Markus Ritter, Markus Paulmichl, Peter Deetjen, Florian Lang, Martin Gschwentner, Johannes Fuerst

Publikováno v: Cellular Physiology and Biochemistry. 11:1-18

The Na(+)/H(+) exchangers (NHEs) are among the major ion transporters involved in cell volume regulation. NHE activation leads to a cellular influx of Na(+) ions and extrusion of H(+) ions, which are readily replenished from intracellular buffers. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::791e221dc8f2d1db966bf63cccdf79f3
https://doi.org/10.1159/000047787

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Cloning of the Swelling-Dependent Chloride Channel lCln Homologue from Zebra Fish

Autor: Peter Deetjen, Ulrich O. Nagl, Andreas Schmarda, Sabine Hofer, Johannes Fürst, Martin Gschwentner, Markus Paulmichl

Publikováno v: Cellular Physiology and Biochemistry. 7:298-302

Using expression cloning techniques, a protein was isolated which gave rise to an outwardly rectifying chloride current after expression in Xenopus laevis oocytes [Paulmichl et al., Nature 1992;356:238-241]. We termed this protein ICln and found it t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cddad0014b915c3afb370779aa3333e1
https://doi.org/10.1159/000154885

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Chromosomal Localization of the Genes (CLNS1A and CLNS1B) Coding for the Swelling-Dependent Chloride Channel ICln

Autor: Martin Erdel, Peter Deetjen, Luis J. V. Galietta, Martin Gschwentner, Markus Paulmichl, Germar M. Pinggera, Andreas Schmarda, Marco Seri, Gerd Utermann, Ulrich O. Nagl, Christoph Duba

Publikováno v: Genomics. 38:438-441

IClnis a cloned chloride channel paramount for regulatory volume decrease. Two different loci that carry the coding region for IClnwere identified in the human genome. By PCR strategies an intronless copy of the gene was located on chromosome 6 at po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d246ab69bcc8a7aced2b80a5c8017f
https://doi.org/10.1006/geno.1996.0651

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Fluorescence-optical measurements of chloride movements in cells using the membrane-permeable dye diH-MEQ

Autor: G Buemberger, Andreas Jungwirth, Johannes Fürst, Martin Gschwentner, Markus Paulmichl, Sabine Hofer, Julian Frick, Peter Deetjen, Ewald Wöll

Publikováno v: Pflügers Archiv - European Journal of Physiology. 432:486-493

Fluorescence-optical measurements of the intracellular chloride concentration facilitate identification of chloride movements across the cell membrane of living cells. The two main dyes used for this purpose are 6-methoxy-N-(3-sulfopropyl)quinolinium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10738e2bdaf5e4512024f829535b95d
https://doi.org/10.1007/s004240050160

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Blockade of swelling-induced chloride channels by phenol derivatives

Autor: Andreas Jungwirth, Martin Gschwentner, Peter Deetjen, Markus Paulmichl, Sabine Hofer, Gilbert Reibnegger, Markus Leitinger, Andreas Schmarda, J. Frick, Alex Susanna, Markus Ritter, Germar M. Pinggera, Ewald Wöll

Publikováno v: British Journal of Pharmacology. 118:41-48

1. In NIH3T3 fibroblasts, the chloride channel involved in regulatory volume decrease (RVD) was identified as ICln, a protein isolated from a cDNA library derived from Madin Darby canine Kidney (MDCK) cells. ICln expressed in Xenopus laevis oocytes g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6b5d15150306140babb0a4142f2f2d
https://doi.org/10.1111/j.1476-5381.1996.tb15364.x

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Antiviral Drugs from the Nucleoside Analog Family Block Volume-Activated Chloride Channels

Autor: Peter Deetjen, Alex Susanna, Markus Ritter, Andreas Laich, Ewald Wöll, Helmut Ellemunter, Germar M. Pinggera, Ulrich O. Nagl, Andreas Schmarda, Martin Gschwentner, Markus Paulmichl, Hartwig P. Huemer

Publikováno v: Molecular Medicine. 1:407-417

The antiviral drugs AZT and acyclovir are generally used in the treatment of infections with human immunodeficiency virus (HIV) and herpes simplex virus (HSV). These substances are known to impede virus replication by premature nucleic acid chain ter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::86065566f94b099ef3e5f101564fdd23
https://doi.org/10.1007/bf03401578

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Insight into the Structure-Function Relation of Chloride Channels

Autor: Markus Ritter, Werner Waitz, Markus Paulmichl, Georgi Kanin, Peter Deetjen, Martin Gschwentner, Ewald Wöll, Andreas Schmarda, Helmut Ellemunter

Publikováno v: Cellular Physiology and Biochemistry. 3:374-387

Chloride channels are highly selective transport proteins ubiquitously expressed in eukaryotic cells. Biophysical methods allow discrimination between several different types of chloride channels with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8512b70fd9fc3f2feb5ad74e6269239b
https://doi.org/10.1159/000154699

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