Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Peter D. Sutherland"'
Autor:
Margaret M. Centenera, Theresa E. Hickey, Shalini Jindal, Natalie K. Ryan, Preethi Ravindranathan, Hisham Mohammed, Jessica L. Robinson, Matthew J. Schiewer, Shihong Ma, Payal Kapur, Peter D. Sutherland, Clive E. Hoffmann, Claus G. Roehrborn, Leonard G. Gomella, Jason S. Carroll, Stephen N. Birrell, Karen E. Knudsen, Ganesh V. Raj, Lisa M. Butler, Wayne D. Tilley
Publikováno v:
Molecular Oncology, Vol 12, Iss 9, Pp 1608-1622 (2018)
Breast and prostate cancer research to date has largely been predicated on the use of cell lines in vitro or in vivo. These limitations have led to the development of more clinically relevant models, such as organoids or murine xenografts that utiliz
Externí odkaz:
https://doaj.org/article/0552f838da6a4c13b4e0ce9e34c20273
Autor:
David J. Horsfall, Wayne D. Tilley, Robert L. Sutherland, Gail P. Risbridger, Judith A. Clements, Hong Wang, Ying Dong, James G. Kench, Hemamali Samaratunga, Peter D. Sutherland, Villis R. Marshall, Penelope A. Cohen, Thomas J. Dodd, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Background: Knowledge of preanalytic conditions that biospecimens are subjected to is critically important because novel surgical procedures, tissue sampling, handling, and storage might affect biomarker expression or invalidate tissue samples as ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314c28ba6ec030e89761b1209eac8858
https://doi.org/10.1158/1055-9965.c.6514812.v1
https://doi.org/10.1158/1055-9965.c.6514812.v1
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 66KB, Immunohistochemistry methodology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf889859efab3c95aa4266aa0c2a5ef
https://doi.org/10.1158/1078-0432.22454438.v1
https://doi.org/10.1158/1078-0432.22454438.v1
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 92KB, (A) PC-3 and (B) LNCaP prostate cancer cells were cultured in medium containing vehicle or 40nM 17-AAG for 96 hours, stained with propidium iodide and analysed by flow cytometry. Cell cycle distibution was determined using FlowJo soft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6855232b4e35afdf18005a9a72c5edf1
https://doi.org/10.1158/1078-0432.22454450
https://doi.org/10.1158/1078-0432.22454450
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 70KB, Primary antibodies used for immunoblotting and immunohistochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb522e66dc63023754d621d624a0c76
https://doi.org/10.1158/1078-0432.22454441
https://doi.org/10.1158/1078-0432.22454441
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 158KB, Hsp90 inhibitors cause dose dependent inhibition of growth and induction of death in LNCaP prostate cancer cells. LNCaP cells were cultured in medium containing the indicated doses of (A&B) AUY922, (C&D) HSP990 or (E&F) 17-AAG. Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b73902f6d5b2161c4474f70f2aceda0
https://doi.org/10.1158/1078-0432.22454453
https://doi.org/10.1158/1078-0432.22454453
Autor:
David J. Horsfall, Wayne D. Tilley, Robert L. Sutherland, Gail P. Risbridger, Judith A. Clements, Hong Wang, Ying Dong, James G. Kench, Hemamali Samaratunga, Peter D. Sutherland, Villis R. Marshall, Penelope A. Cohen, Thomas J. Dodd, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Supplementary Table 1 from Comparative Biomarker Expression and RNA Integrity in Biospecimens Derived from Radical Retropubic and Robot-Assisted Laparoscopic Prostatectomies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edcd3afaae634c45d7cbd360d655244
https://doi.org/10.1158/1055-9965.22435245
https://doi.org/10.1158/1055-9965.22435245
Autor:
David J. Horsfall, Wayne D. Tilley, Robert L. Sutherland, Gail P. Risbridger, Judith A. Clements, Hong Wang, Ying Dong, James G. Kench, Hemamali Samaratunga, Peter D. Sutherland, Villis R. Marshall, Penelope A. Cohen, Thomas J. Dodd, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Supplementary Table 2 from Comparative Biomarker Expression and RNA Integrity in Biospecimens Derived from Radical Retropubic and Robot-Assisted Laparoscopic Prostatectomies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a36b19907b701113c1586916698cb9
https://doi.org/10.1158/1055-9965.22435242.v1
https://doi.org/10.1158/1055-9965.22435242.v1
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
PDF file, 581KB, Representative (A) Ki67 and (B) cleaved caspase-3 immunostaining in tumors cultured for 48 hours with vehicle control or increasing doses of Hsp90 inhibitors as indicated. Bar = 50�m.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85952675a728c46ff45193719f49fe45
https://doi.org/10.1158/1078-0432.22454444.v1
https://doi.org/10.1158/1078-0432.22454444.v1
Autor:
Lisa M. Butler, Wayne D. Tilley, Trina Yeadon, Karen E. Knudsen, Ganesh V. Raj, Howard I. Scher, Peter D. Sutherland, Gail P. Risbridger, Renea A. Taylor, Shalini Jindal, Adrienne R. Hanson, Joanna L. Gillis, Margaret M. Centenera
Purpose: Targeting Hsp90 has significant potential as a treatment for prostate cancer, but prototypical agents such as 17-allylamino-17 demethoxygeldanamycin (17-AAG) have been ineffective in clinical trials. Recently, a phase I study aimed at defini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d54be0ca67b745c73e1afb0196a09bb
https://doi.org/10.1158/1078-0432.c.6522749
https://doi.org/10.1158/1078-0432.c.6522749