Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Peter D. Hobbs"'
Publikováno v:
Chemistry and Biology of Synthetic Retinoids ISBN: 9781351070638
Chemistry and Biology of Synthetic Retinoids
Chemistry and Biology of Synthetic Retinoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba783c2953274e757a73b2f7114f9b23
https://doi.org/10.1201/9781351070638-16
https://doi.org/10.1201/9781351070638-16
Publikováno v:
Chemistry and Biology of Synthetic Retinoids ISBN: 9781351070638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d440afb4dee4d81371ac9ddf86540c0
https://doi.org/10.1201/9781351070638-14
https://doi.org/10.1201/9781351070638-14
Autor:
Richard E. Fine, Lidia Sambucetti, Peter D. Hobbs, Joy M. Calaoagan, Barbara G. Sato, Sarah J. Duellman, Keith R. Laderoute, Wan-Ru Chao, Boris Klebansky, Nathan Collins
Publikováno v:
Biochemical Pharmacology. 80:819-826
The orphan nuclear receptor estrogen-related receptor α (ERRα) has been implicated in the development of various human malignancies, including breast, prostate, ovary, and colon cancer. ERRα, bound to a co-activator protein (e.g., peroxisome proli
Autor:
Christopher W. Lange, Sharon Y. James, Mark Leid, Gang Liu, Ling Jong, Danni L. Harris, Marcia I. Dawson, Lulu Farhana, Joseph A. Fontana, and Arun K. Rishi, Nathalie Bruey-Sedano, Xiao-kun Zhang, Valerie J. Peterson, Peter D. Hobbs
Publikováno v:
Journal of Medicinal Chemistry. 47:3518-3536
The retinoid 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) and its active analogues induce cell-cycle arrest and programmed cell death (apoptosis) in cancer cells independently of retinoic acid receptor (RAR) interaction.
Identification of a unique binding protein specific for a novel retinoid inducing cellular apoptosis
Autor:
Wan-Ru Chao, Braham Shroot, Marcia I. Dawson, Arun K. Rishi, Peter D. Hobbs, Yuxiang Zhang, Ling Jong, Valerie J. Peterson, Joseph A. Fontana, Uwe Reichert, Jing Song Lu, C. Alex Hsu, Mark Leid
Publikováno v:
International Journal of Cancer. 86:474-479
The retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN, CD437) induces apoptosis in a variety of cell types, many of which are cancer cells that resist the antiproliferative and/or differentiating effects of retinoids. Wh
Autor:
Ajit K. Verma, Guo Quan Chen, Lawrence Toll, Braham Shroot, Longchuan Bai, Jian Gu, Wan Ru Chao, Marcia I. Dawson, Donald L. Hill, Xiao-kun Zhang, Ju Hui Park, Ling Jong, Juanita L. Merchant, Linda Dousman, Scott M. Thacher, Peter D. Hobbs, Anissa Agadir, Nahid Waleh, Roshantha A.S. Chandraratna
Publikováno v:
International Journal of Cancer. 91:8-21
Evaluation of retinoic acid receptor (RAR) subtype-selective alpha and gamma agonists and antagonists and a retinoid X receptor (RXR) class-selective agonist for efficacy at inhibiting both induction of ornithine decarboxylase (ODC) by the tumor prom
Publikováno v:
Biochemistry. 38:6732-6740
The interaction of retinoid X receptor alpha with 9-cis-retinoic acid was studied using stopped-flow fluorescence spectroscopy. Transient kinetic analyses of this interaction suggest a two-step binding mechanism involving a rapid, enthalpically drive
Autor:
Marcia I. Dawson, John C. Reed, Braham Shroot, Xiao-kun Zhang, Ru Liu, Bingzhen Lin, Yun Zheng, Dan Mercola, Joseph A. Fontana, Peter D. Hobbs, Frédéric Bost, Anissa Agadir, Guo-quan Chen, Yin Li
Publikováno v:
Europe PubMed Central
6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (AHPN or CD437), originally identified as a retinoic acid receptor gamma-selective retinoid, was previously shown to induce growth inhibition and apoptosis in human breast cancer cells
Autor:
Anissa Agadir, Peter D. Hobbs, Marcia I. Dawson, Ling Jong, Yin Li, Mi-Ock Lee, Xiao-kun Zhang
Publikováno v:
International Journal of Cancer. 75:88-95
Retinoids regulate the growth and differentiation of human tracheobronchial epithelial cells. In this study, we investigated the effects of all-trans-retinoic acid (trans-RA) and receptor class-selective retinoids on the growth and apoptosis of human
Autor:
Marcia I. Dawson, Wan-Ru Chao, Yun Zheng, Braham Shroot, Xiao-kun Zhang, Qiao Wu, Peter D. Hobbs, Ling Jong
Publikováno v:
Cancer Letters. 115:1-7
Comparison of the adherent growth inhibition of NIH:OVCAR-3 ovarian cancer cells by retinoid receptor class-selective and subtype-selective compounds with their receptor binding affinities and transcriptional activation activities indicated no correl