Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Peter D Lukasiewicz"'
Publikováno v:
J Neurophysiol
In the retina, modulation of the amplitude of dim visual signals primarily occurs at axon terminals of rod bipolar cells (RBCs). GABA and glycine inhibitory neurotransmitter receptors and the excitatory amino acid transporter 5 (EAAT5) modulate the R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82903ea33a4de2d104d9fa55be101403
https://pubmed.ncbi.nlm.nih.gov/32233906
https://pubmed.ncbi.nlm.nih.gov/32233906
Autor:
Peter D. Lukasiewicz, Li Yin, Gregory W. Bligard, Clay F. Semenkovich, Rithwick Rajagopal, Sheng Zhang
Publikováno v:
Diabetes
Obesity predisposes to human type 2 diabetes, the most common cause of diabetic retinopathy. To determine if high-fat diet–induced diabetes in mice can model retinal disease, we weaned mice to chow or a high-fat diet and tested the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739f3a7bbb2dd5085a7de5c15eb13170
https://doi.org/10.2337/db15-1255
https://doi.org/10.2337/db15-1255
Publikováno v:
Visual Neuroscience. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b046349b4f11ea165fc1076bc3a8fc9
https://doi.org/10.1017/s0952523817000384
https://doi.org/10.1017/s0952523817000384
Autor:
Peter D. Lukasiewicz, Robert Purgert
Publikováno v:
Journal of Neurophysiology. 114:1757-1772
The retina is the first stage of visual processing. It encodes elemental features of visual scenes. Distinct cone bipolar cells provide the substrate for this to occur. They encode visual information, such as color and luminance, a principle known as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0010f91529b609246ed694feab0eeb52
https://doi.org/10.1152/jn.00287.2015
https://doi.org/10.1152/jn.00287.2015
Autor:
Victor I. Govardovskii, Peter D. Lukasiewicz, Loryn Rikimaru, Alexander V. Kolesnikov, Steven J. Fliesler, Oleg G. Kisselev, Vladimir J. Kefalov, Anne K. Hennig
Publikováno v:
The Journal of Neuroscience. 31:8067-8077
A fundamental question of cell signaling biology is how faint external signals produce robust physiological responses. One universal mechanism relies on signal amplification via intracellular cascades mediated by heterotrimeric G-proteins. This high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c595af95abdae9a88efbc46ba189bc
https://doi.org/10.1523/jneurosci.0174-11.2011
https://doi.org/10.1523/jneurosci.0174-11.2011
Autor:
Erika D. Eggers, Peter D. Lukasiewicz
Publikováno v:
Visual Neuroscience. 28:95-108
Bipolar cells (BCs) are critical relay neurons in the retina that are organized into parallel signaling pathways. The three main signaling pathways in the mammalian retina are the rod, ON cone, and OFF cone BCs. Rod BCs mediate incrementing dim light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e361673cbdbd7aeb0b75a570e863e492
https://doi.org/10.1017/s0952523810000209
https://doi.org/10.1017/s0952523810000209
Publikováno v:
The Journal of Physiology. 582:569-582
Diverse retinal outputs are mediated by ganglion cells that receive excitatory input from distinct classes of bipolar cells (BCs). These classes of BCs separate visual signals into rod, ON and OFF cone pathways. Although BC signalling is a major dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e39701cc2c1009041415c19c225f2c2
https://doi.org/10.1113/jphysiol.2007.131763
https://doi.org/10.1113/jphysiol.2007.131763
Autor:
Kevin K. Ohlemiller, Abdul Waheed, William S. Sly, Timothy Becker, Judith Mosinger Ogilvie, Gul N. Shah, Peter D. Lukasiewicz, Anne K. Hennig, Barbara Ulmasov
Publikováno v:
Proceedings of the National Academy of Sciences. 104:8514-8519
Members of the carbonic anhydrase (CA) family play an important role in the regulation of pH, CO2, ion, and water transport. CA IV and CA XIV are membrane-bound isozymes expressed in the eye. CA IV immunostaining is limited to the choriocapillaris ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ff2feafd0cdf379a4cb05bbc9b0e10
https://doi.org/10.1073/pnas.0702899104
https://doi.org/10.1073/pnas.0702899104
Publikováno v:
Neuron. 50(6):923-935
SummarySensory information is thought to be modulated by presynaptic inhibition. Although this form of inhibition is a well-studied phenomenon, it is still unclear what role it plays in shaping sensory signals in intact circuits. By visually stimulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939b2e1e8ce16f703467c46447eeab79
Autor:
Peter D. Lukasiewicz, Erika D. Eggers
Publikováno v:
The Journal of Physiology. 572:215-225
Rod bipolar cells relay visual signals evoked by dim illumination from the outer to the inner retina. GABAergic and glycinergic amacrine cells contact rod bipolar cell terminals, where they modulate transmitter release and contribute to the receptive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69c66da3c8959148470a35b1c2e2fcd7
https://doi.org/10.1113/jphysiol.2005.103648
https://doi.org/10.1113/jphysiol.2005.103648