Zobrazeno 1 - 10
of 757
pro vyhledávání: '"Peter D, Gluckman"'
Autor:
Jia Xu, Rebbeca M. Duar, Baoling Quah, Min Gong, Felicia Tin, Penny Chan, Choon Kiat Sim, Kok Hian Tan, Yap Seng Chong, Peter D. Gluckman, Steven A. Frese, David Kyle, Neerja Karnani
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
BackgroundThe loss of ancestral microbes, or the “disappearing microbiota hypothesis” has been proposed to play a critical role in the rise of inflammatory and immune diseases in developed nations. The effect of this loss is most consequential du
Externí odkaz:
https://doaj.org/article/cd73a66061894219b3db25b76b10a3d3
Autor:
Jonas G. Miller, Peter D. Gluckman, Marielle V. Fortier, Yap Seng Chong, Michael J. Meaney, Ai Peng Tan, Ian H. Gotlib
Publikováno v:
Developmental Cognitive Neuroscience, Vol 67, Iss , Pp 101392- (2024)
Early life adversity has been posited to influence the pace of structural neurodevelopment. Most research, however, has relied on cross-sectional data, which do not reveal whether the pace of neurodevelopmental change is accelerated or slowed followi
Externí odkaz:
https://doaj.org/article/bcfb02ff17a0429f96c48d6bc47e5f05
Autor:
Eamon Fitzgerald, Mojun Shen, Hannah Ee Juen Yong, Zihan Wang, Irina Pokhvisneva, Sachin Patel, Nicholas O’Toole, Shiao-Yng Chan, Yap Seng Chong, Helen Chen, Peter D. Gluckman, Jerry Chan, Patrick Kia Ming Lee, Michael J. Meaney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Pathological placental inflammation increases the risk for several adult disorders, but these mediators are also expressed under homeostatic conditions, where their contribution to adult health outcomes is unknown. Here we define an inflamma
Externí odkaz:
https://doaj.org/article/562ebed74c8f4dc0a29125be9a4443f5
Autor:
Ling-Wei Chen, Sharon Ng, Mya-Thway Tint, Navin Michael, Suresh Anand Sadananthan, Yi Ying Ong, Wen Lun Yuan, Ze-Ying Chen, Chia-Yang Chen, Keith M. Godfrey, Kok Hian Tan, Peter D. Gluckman, Yap-Seng Chong, Johan G. Eriksson, Fabian Yap, Yung Seng Lee, Marielle V. Fortier, Sendhil S. Velan, Shiao-Yng Chan
Publikováno v:
Environment International, Vol 183, Iss , Pp 108340- (2024)
Background: The influence of prenatal exposure to per- and poly- fluoroalkyl substances (PFAS) on birth size and offspring adiposity is unclear, especially for the newer, shorter-chained replacement PFAS. Methods: In the GUSTO multi-ethnic Singaporea
Externí odkaz:
https://doaj.org/article/a7d2592808184770b0862b11eed4fd12
Autor:
Li Chen, Sartaj Ahmad Mir, Anne K. Bendt, Esther W. L. Chua, Kothandaraman Narasimhan, Karen Mei-Ling Tan, See Ling Loy, Kok Hian Tan, Lynette P. Shek, Jerry Chan, Fabian Yap, Michael J. Meaney, Shiao-Yng Chan, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Neerja Karnani, Markus R. Wenk
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract Background Adaptations in lipid metabolism are essential to meet the physiological demands of pregnancy and any aberration may result in adverse outcomes for both mother and offspring. However, there is a lack of population-level studies to
Externí odkaz:
https://doaj.org/article/679f327d8a4d4d44a9bb74f4acdd4ab7
Autor:
Sartaj Ahmad Mir, Li Chen, Satvika Burugupalli, Bo Burla, Shanshan Ji, Adam Alexander T. Smith, Kothandaraman Narasimhan, Adaikalavan Ramasamy, Karen Mei-Ling Tan, Kevin Huynh, Corey Giles, Ding Mei, Gerard Wong, Fabian Yap, Kok Hian Tan, Fiona Collier, Richard Saffery, Peter Vuillermin, Anne K. Bendt, David Burgner, Anne-Louise Ponsonby, Yung Seng Lee, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Peter J. Meikle, Markus R. Wenk, Neerja Karnani
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Lipids play a vital role in health and disease, but changes to their circulating levels and the link with obesity remain poorly characterized in expecting mothers and their offspring in early childhood. Methods LC-MS/MS-based quan
Externí odkaz:
https://doaj.org/article/2a524f4cbd2448029ad0b8261c9144bb
Autor:
Elaine Kwang Hsia Tham, Hai-Yan Xu, Xiuju Fu, Rick Siow Mong Goh, Peter D. Gluckman, Yap-Seng Chong, Fabian Yap, Lynette Pei-Chi Shek, Oon Hoe Teoh, Joshua Gooley, Daniel Yam-Thiam Goh, Nora Schneider, Michael J. Meaney, Shirong Cai, Birit F. P. Broekman
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
PurposeThis study explores the association between the duration and variation of infant sleep trajectories and subsequent cognitive school readiness at 48–50 months.MethodsParticipants were 288 multi-ethnic children, within the Growing Up in Singap
Externí odkaz:
https://doaj.org/article/40cd26ab9ae6429580b61461ec8cb085
Autor:
Debbie S. Thompson, Tamika Y. N. Royal-Thomas, Ingrid A. Tennant, Deanne P. Soares, Christopher D. Byrne, Terrence E. Forrester, Peter D. Gluckman, Michael S. Boyne
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract The association between severe acute malnutrition (SAM) in early childhood and liver fat in adults is unknown. We hypothesized that exposure to SAM, especially severe wasting, is associated with fatty liver later in life. In this observation
Externí odkaz:
https://doaj.org/article/6fc935d4d91040378571a66dd057502f
Autor:
Li Chen, Karen Tan Mei Ling, Min Gong, Mary F. F. Chong, Kok Hian Tan, Yap Seng Chong, Michael J. Meaney, Peter D. Gluckman, Johan G. Eriksson, Neerja Karnani
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Telomere length (TL) and its attrition are important indicators of physiological stress and biological aging and hence may vary among individuals of the same age. This variation is apparent even in newborns, suggesting potential e
Externí odkaz:
https://doaj.org/article/f773bd804fd14d6893d96f568754da2f
Autor:
Nandini Anant, Divjyot Kaur, Ranjani Nadarajan, Desiree Y Phua, Yap Seng Chong, Peter D Gluckman, Fabian Yap, Helen Chen, Birit Broekman, Michael J Meaney, Yuen-Siang Ang
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286197 (2023)
Childhood-onset depression has adverse consequences that are sustained into adulthood, which increases the significance of detection in early childhood. The Children's Depression Inventory (CDI) is used globally in evaluating depressive symptom sever
Externí odkaz:
https://doaj.org/article/a4b98647750c44b982d2e75d5b4949c8