Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Peter Czuczman"'
Autor:
Laura Beaton, Henry F.J. Tregidgo, Sami A. Znati, Sharon Forsyth, Nicholas Counsell, Matthew J. Clarkson, Steven Bandula, Manil Chouhan, Helen L. Lowe, May Zaw Thin, Julian Hague, Dinesh Sharma, Joerg-Matthias Pollok, Brian R. Davidson, Jowad Raja, Graham Munneke, Daniel J. Stuckey, Zainab A. Bascal, Paul E. Wilde, Sarah Cooper, Samantha Ryan, Peter Czuczman, Eveline Boucher, John A. Hartley, David Atkinson, Andrew L. Lewis, Marnix Jansen, Tim Meyer, Ricky A. Sharma
Publikováno v:
Journal of vascular and interventional radiology : JVIR. 33(9)
To assess the safety and tolerability of a vandetanib-eluting radiopaque embolic (BTG-002814) for transarterial chemoembolization (TACE) in patients with resectable liver malignancies.The VEROnA clinical trial was a first-in-human, phase 0, single-ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b33332a99f4fa341c5777365d9389f0
https://pubmed.ncbi.nlm.nih.gov/35526675
https://pubmed.ncbi.nlm.nih.gov/35526675
Autor:
Hugh Kilpatrick, Z. A. Bascal, Peter Czuczman, Alban Denys, Andrew L. Lewis, Rhys Whomsley, David Grey
Publikováno v:
Theranostics, vol. 7, no. 8, pp. 2164-2176
To evaluate the plasma and tissue pharmacokinetics, safety and toxicity following intra-arterial hepatic artery administration of Vandetanib (VTB)-eluting Radiopaque Beads (VERB) in healthy swine. In a first phase, healthy swine were treated with hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26d962737625d69577515e2d40c2ea1
https://doi.org/10.7150/thno.19652
https://doi.org/10.7150/thno.19652
Autor:
Peter Czuczman, Z. A. Bascal, Florentina Pascale, Andrew L. Lewis, Rafael Duran, Rhys Whomsley, Hugh Kilpatrick, Samantha Ryan, Alban Denys, Julien Namur
Publikováno v:
Radiology
Background Transarterial chemoembolization with cytotoxic drugs is standard treatment for unresectable intermediate-stage hepatocellular carcinoma but achieves suboptimal outcomes because of hypoxic stress and the production of detrimental proangioge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab30ecbe64628297ed7efc7ed3e58af
https://pubmed.ncbi.nlm.nih.gov/31617799
https://pubmed.ncbi.nlm.nih.gov/31617799
Autor:
Ricky A. Sharma, Graham Munneke, Tim Meyer, Samantha Ryan, Joerg-Matthias Pollok, Matthew J. Clarkson, Sarah Cooper, Jowad Raja, Julian Hague, Laura Beaton, Sami A. Znati, Helen Lowe, Dinesh K. Sharma, Paul E Wilde, Henry F. J. Tregidgo, Z. A. Bascal, John A. Hartley, Peter Czuczman, Eveline Boucher, Brian R. Davidson, Marnix Jansen, Sharon Forsyth, Steven Bandula, May Zaw Thin, Manil D Chouhan, Daniel J. Stuckey, Andrew L. Lewis
Publikováno v:
JMIR Research Protocols
Background Transarterial chemoembolization (TACE) is the current standard of care for patients with intermediate-stage hepatocellular carcinoma (HCC) and is also a treatment option for patients with liver metastases from colorectal cancer. However, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5385589a8b29c22d06c6043e8ab89c76
http://europepmc.org/articles/PMC6777276
http://europepmc.org/articles/PMC6777276
Autor:
Laura Beaton, Henry F J Tregidgo, Sami A Znati, Sharon Forsyth, Matthew J Clarkson, Steven Bandula, Manil Chouhan, Helen L Lowe, May Zaw Thin, Julian Hague, Dinesh Sharma, Joerg-Matthias Pollok, Brian R Davidson, Jowad Raja, Graham Munneke, Daniel J Stuckey, Zainab A Bascal, Paul E Wilde, Sarah Cooper, Samantha Ryan, Peter Czuczman, Eveline Boucher, John A Hartley, Andrew L Lewis, Marnix Jansen, Tim Meyer, Ricky A Sharma
BACKGROUND Transarterial chemoembolization (TACE) is the current standard of care for patients with intermediate-stage hepatocellular carcinoma (HCC) and is also a treatment option for patients with liver metastases from colorectal cancer. However, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::207b42a1cd162a61f956d9f90b2f245c
https://doi.org/10.2196/preprints.13696
https://doi.org/10.2196/preprints.13696
Autor:
Alban, Denys, Peter, Czuczman, David, Grey, Zainab, Bascal, Rhys, Whomsley, Hugh, Kilpatrick, Andrew L, Lewis
Publikováno v:
Theranostics
PURPOSE: To evaluate the plasma and tissue pharmacokinetics, safety and toxicity following intra-arterial hepatic artery administration of Vandetanib (VTB)-eluting Radiopaque Beads (VERB) in healthy swine. MATERIALS AND METHODS: In a first phase, hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c05334184bb4fc059c3003aa04389cba
https://pubmed.ncbi.nlm.nih.gov/28740542
https://pubmed.ncbi.nlm.nih.gov/28740542
Autor:
Andrew L. Lewis, Gary Phillips, Wendy M. Macfarlane, Peter Czuczman, Andrew W. Lloyd, Alice Hagan
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 101
Since their introduction around a decade ago, embolic drug-eluting beads (DEBs) have become a well-established treatment option for the locoregional transarterial treatment of hepatic malignancies. Despite this success, the therapy is seen to be limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8247fd6d8ef7bd5d31df9dc0ec7f9b
https://pubmed.ncbi.nlm.nih.gov/28132823
https://pubmed.ncbi.nlm.nih.gov/28132823
Publikováno v:
Journal of Controlled Release. 127:70-78
The distribution of the active lactone and the inactive carboxylate forms of irinotecan released from drug eluting beads composed of a sulfonate-modified PVA hydrogel was studied in order to ascertain the interaction between irinotecan, a water-solub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce322164c7ac1ea0641e138ed2c9dd54
https://doi.org/10.1016/j.jconrel.2007.12.012
https://doi.org/10.1016/j.jconrel.2007.12.012
Autor:
David J. R. Foster, John W. Finnie, S. Ting Chung, Andrew L. Lewis, Timothy R. Kuchel, Susan Porter, Peter Czuczman, Rachel R. Holden
Publikováno v:
Journal of Materials Science. Materials in Medicine
Irinotecan eluting embolization beads (DEBIRI) are currently being evaluated in the clinic for the treatment of colorectal cancer metastases to the liver. The aim of this study was to determine the safety and pharmacokinetics associated with two cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a8e33cc668e07742cdf0dab1d22c9a
https://pubmed.ncbi.nlm.nih.gov/23015264
https://pubmed.ncbi.nlm.nih.gov/23015264
Autor:
Danielle Vanbeckbergen, Peter Czuczman, Andrew L. Lewis, Jean-Daniel Hecq, Laurence Galanti, Jacques Jamart, Ting Chung, Alexandre Athanosopoulos
Publikováno v:
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 19(1)
Purpose: Evaluation of doxorubicin stability over time when stored into the DC Bead embolic agent, in various containers, which are used for the delivery of the doxorubicin-loaded beads to the patients for up to 14 days under refrigerated conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d060785af489a1662c8010a7149e99
https://pubmed.ncbi.nlm.nih.gov/22801955
https://pubmed.ncbi.nlm.nih.gov/22801955