Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Peter Czabotar"'
Autor:
Ruitao Jin, Sitong He, Katrina A. Black, Oliver B. Clarke, Di Wu, Jani R. Bolla, Paul Johnson, Agalya Periasamy, Ahmad Wardak, Peter Czabotar, Peter M. Colman, Carol V. Robinson, Derek Laver, Brian J. Smith, Jacqueline M. Gulbis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The Kir potassium channels are known to operate and gate without a major conformational change. Here, the authors identify the permeation gate of Kir channels as a steric plug within the conduction pathway, describing how tightly associated anionic l
Externí odkaz:
https://doaj.org/article/400ab475f64247199cf3b4d67129ff32
Autor:
Isabelle Lucet, Joanne Hildebrand, Peter Czabotar, Jian-Guo Zhang, Nicos Nicola, John Silke, Jeffrey Babon, James Murphy
Publikováno v:
Bio-Protocol, Vol 4, Iss 11 (2014)
This protocol describes a robust technique for the measurement of pseudokinase-ligand interaction by a fluorescence-based Thermal Shift Assay (TSA). Pseudokinases are kinase-like proteins that have recently emerged as crucial regulators of signal tra
Externí odkaz:
https://doaj.org/article/f93fcc35f38f4138b79dfc6a4878abfa
Autor:
Alan Cowman, Anthony Hodder, Janni Christensen, Stephen Scally, Tony Triglia, Anna Ngo, Richard Birkinshaw, Brodie Bailey, Paola Favuzza, Melanie Dietrich, Wai-Hong Tham, Peter Czabotar, Kym Lowes, Zhuyan Guo, Nicholas Murgolo, Manuel Ruiz, John McCauley, Brad Sleebs, David Olsen
Plasmepsin IX (PMIX) and X (PMX) are aspartyl proteases of Plasmodium spp. that play essential roles in parasite egress, invasion and development. Consequently, they are important drug targets for Plasmodium falciparum and P. vivax. WM4 and WM382 are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da25abceb2f5e920a88acdacb60f0535
https://doi.org/10.21203/rs.3.rs-944781/v2
https://doi.org/10.21203/rs.3.rs-944781/v2
Autor:
Anthony Hodder, Janni Christensen, Stephen Scally, Tony Triglia, Anna Ngo, Richard Birkinshaw, Brodie L Bailey, Paola Favuzza, Melanie Dietrich, Wai-Hong Tham, Peter Czabotar, Kym Lowes, Zhuyan Guo, Nicholas Murgolo, Manuel de Lera Ruiz, John McCauley, Brad Sleebs, David Olsen, Alan Cowman
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18256258b2e12a9ea21844e09ff4e768
https://doi.org/10.2139/ssrn.3948205
https://doi.org/10.2139/ssrn.3948205
Autor:
Andrea Maggioni, Peter Czabotar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Inflammation is a protective response of the body’s immune system against harmful stimuli such as pathogenic microorganisms, toxins, or damaged cells. However, if excessive or prolonged, inflammation may be harmful and therefore has to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e030b305e9e3b7cf1f971b8d6274e0b
https://europepmc.org/articles/PMC6462068/
https://europepmc.org/articles/PMC6462068/
Autor:
Sandra, Vogel, Nina, Raulf, Stephanie, Bregenhorn, Martin L, Biniossek, Ulrich, Maurer, Peter, Czabotar, Christoph, Borner
Publikováno v:
The Journal of biological chemistry. 287(12)
Bax is kept inactive in the cytosol by refolding its C-terminal transmembrane domain into the hydrophobic binding pocket. Although energetic calculations predicted this conformation to be stable, numerous Bax binding proteins were reported and sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::efd8fe825773e2f0d164d16252d8e7b4
https://pubmed.ncbi.nlm.nih.gov/22277657
https://pubmed.ncbi.nlm.nih.gov/22277657