Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Peter Cron"'
Autor:
Arnaud Parcellier, Lionel A Tintignac, Elena Zhuravleva, Bettina Dummler, Derek P Brazil, Debby Hynx, Peter Cron, Susanne Schenk, Vesna Olivieri, Brian A Hemmings
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5471 (2009)
BACKGROUND: Mitochondria are central to the metabolism of cells and participate in many regulatory and signaling events. They are looked upon as dynamic tubular networks. We showed recently that the Carboxy-Terminal Modulator Protein (CTMP) is a mito
Externí odkaz:
https://doaj.org/article/a0d3cbef915a41908fd032c7e51d73b3
Autor:
Peter Cronemyr, Maria Huge-Brodin
Publikováno v:
International Journal of Qualitative Methods, Vol 23 (2024)
Research in management needs to contribute to practical relevance and applicability of research results. An approach that acknowledges the needs that emerge from practice and still offers guidance for proper research, is action research. The purpose
Externí odkaz:
https://doaj.org/article/7f1824cb31124fcda6c7953182d105e4
Autor:
Sandrine Bichet, Alexander Hergovich, Luigi Terracciano, Daniel Hess, Lei Zhang, Fengyuan Tang, Peter Cron, Brian A. Hemmings, Debora Schmitz-Rohmer, Debby Hynx, Reto S. Kohler
Publikováno v:
Current Biology
Summary Background Phosphorylation of the transcriptional coactivator YAP1 is a key event in defining Hippo signaling outputs. Previous studies demonstrated that phosphorylation of YAP1 at serine 127 (S127) sequesters YAP1 in the cytoplasm and conseq
Autor:
Peter Cronin, Siobhan McCarthy, Cian Hurley, Tarini Shankar Ghosh, Jakki C. Cooney, Ann-Marie Tobin, Michelle Murphy, Eibhlís M. O’Connor, Fergus Shanahan, Paul W. O’Toole
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionThe chronic inflammatory skin disease Hidradenitis suppurativa (HS) is strongly associated with Crohn’s Disease (CD). HS and CD share clinical similarities and similar inflammatory pathways are upregulated in both conditions. Increased
Externí odkaz:
https://doaj.org/article/f6100021721f40fab2505dee5913ea94
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Labeling a patient “non-compliant” is a form of dehumanization that can deprive the patient of positive human qualities and/or agency in the mind of a physician. The term “non-compliant” is frequently used in medical recor
Externí odkaz:
https://doaj.org/article/9e21a165a69545fdb3bdc2e55863ea16
Autor:
Sandrine Bichet, Daniela Taverna, Fengyuan Tang, Curzio Rüegg, Debby Hynx, Alfred Zippelius, Reto S. Kohler, Alexandra Graff Meyer, Daniela Massi, Manuele G. Muraro, Taha Merghoub, Tim Roloff, Mitchell P. Levesque, Yuhua Wang, Christel Genoud, Francesca Orso, Petra Hirschmann, Huifang Tang, Stephan Dirnhofer, Brian A. Hemmings, Giulio C. Spagnoli, Vincent Prêtre, Andreas Wicki, Reinhard Dummer, Peter Cron, Mario Mandalà, Gongda Xue, Reto Ritschard
Publikováno v:
Oncotarget
BRAF inhibitors (BRAFi) and the combination therapy of BRAF and MEK inhibitors (MEKi) were recently approved for therapy of metastatic melanomas harbouring the oncogenic BRAFV600 mutation. Although these therapies have shown pronounced therapeutic ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd72f6e0c95f7f86566335f309d5ac60
http://hdl.handle.net/11391/1480929
http://hdl.handle.net/11391/1480929
Autor:
Lionel A. Tintignac, Elena Zhuravleva, Peter Cron, Brian A. Hemmings, Lana Bozulic, Arnaud Parcellier, Susanne Schenk
Publikováno v:
Cellular Signalling. 21:639-650
The Carboxy-Terminal Modulator Protein (CTMP) protein was identified as a PKB inhibitor that binds to its hydrophobic motif. Here, we report mitochondrial localization of endogenous and exogenous CTMP. CTMP exhibits a dual sub-mitochondrial localizat
Autor:
Peter Cronau
Publikováno v:
Pacific Journalism Review, Vol 29, Iss 1 & 2 (2023)
Shirley Shackleton said that after her husband Greg was killed in Timor-Leste in October 1975, for seven weeks she became a campaigner for justice for the journalists murdered in Balibo, then after Indonesia invaded in December 1975 she became a camp
Externí odkaz:
https://doaj.org/article/fb6e8747c6874320aa81239e5c22d2fd
Autor:
Shimrit Keddem, Aneeza Agha, Sabrina Morawej, Amy Buck, Peter Cronholm, Sarita Sonalkar, Matthew Kearney
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e43596 (2023)
BackgroundHIV remains a persistent health problem in the United States, especially among women. Approved in 2012, HIV pre-exposure prophylaxis (PrEP) is a daily pill or bimonthly injection that can be taken by individuals at increased risk of contrac
Externí odkaz:
https://doaj.org/article/e41f42024e25420babd785ef2e6112ae
Autor:
Peter Cron, Jing Yang, Valerie M. Good, Brian A. Hemmings, David Barford, Daniel Hess, Vivienne Thompson
Publikováno v:
Molecular Cell. 9:1227-1240
Protein kinase B/Akt plays crucial roles in promoting cell survival and mediating insulin responses. The enzyme is stimulated by phosphorylation at two regulatory sites: Thr 309 of the activation segment and Ser 474 of the hydrophobic motif, a conser