Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter Ciraolo"'
Autor:
Eric P. Smith, Mary B. Palascak, Christopher J. Lindsell, Peter Ciraolo, Robert M. Cohen, Paramjit K. Khera, Clinton H. Joiner, Robert S. Franco
Publikováno v:
Blood. 112:4284-4291
Although red blood cell (RBC) life span is a known determinant of percentage hemoglobin A1c (HbA1c), its variation has been considered insufficient to affect clinical decisions in hematologically normal persons. However, an unexplained discordance be
Autor:
Donald L. Rucknagel, Mary B. Palascak, Peter Ciraolo, Robert S. Franco, Zahida Yasin, Clinton H. Joiner
Publikováno v:
Blood. 108:1073-1076
The determinants of sickle red blood cell (RBC) life span have not been well-defined but may include both intrinsic factors (eg, the tendency to sickle) and extrinsic factors (eg, the capacity of the reticuloendothelial system to remove defective RBC
Publikováno v:
Blood. 111(2)
Band 3, the major protein of the human erythrocyte membrane, associates with multiple metabolic, ion transport, and structural proteins. Functional studies demonstrate that the oxygenation state of the erythrocyte regulates cellular properties perfor
Publikováno v:
Blood. 112:4792-4792
Chronic Transfusion Therapy (CTT) is increasingly important in the treatment of sickle cell disease (SCD), and is now the standard of care for primary and secondary stroke prevention in pediatric patients. However, little is known about its effects o
Publikováno v:
Blood. 110:140-140
Band 3, the major protein of the human erythrocyte membrane, associates with multiple metabolic, ion transport, and structural proteins of the cell. Functional studies demonstrate that the oxygenation state of the erythrocyte regulates metabolic, ion
Publikováno v:
Blood. 108:1241-1241
Red blood cell (RBC) membrane phosphatidylserine (PS) is normally confined to the inner leaflet. In sickle RBC, however, PS externalization has been observed and may contribute to thrombogenesis, endothelial adhesion, and shortened RBC lifespan. Incr
Autor:
Peter Ciraolo, Donald L. Rucknagel, Zahida Yasin, Robert S. Franco, Mary B. Palascak, Clinton H. Joiner
Publikováno v:
Blood. 104:3588-3588
Percent fetal hemoglobin (HbF) is an important determinant of clinical severity in sickle cells disease (SCD). There is a dichotomous distribution of HbF in sickle cells, with one population containing 20–25% HbF (F cells) and another in which HbF